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Results: 1 to 20 of 111

1.

Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease.

Ikonomovic MD, Klunk WE, Abrahamson EE, Wuu J, Mathis CA, Scheff SW, Mufson EJ, DeKosky ST.

Neurology. 2011 Jul 5;77(1):39-47. doi: 10.1212/WNL.0b013e3182231419. Epub 2011 Jun 22.

PMID:
21700583
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

DeKosky ST, Ikonomovic MD, Styren SD, Beckett L, Wisniewski S, Bennett DA, Cochran EJ, Kordower JH, Mufson EJ.

Ann Neurol. 2002 Feb;51(2):145-55.

PMID:
11835370
[PubMed - indexed for MEDLINE]
3.

Basal cerebral metabolism may modulate the cognitive effects of Abeta in mild cognitive impairment: an example of brain reserve.

Cohen AD, Price JC, Weissfeld LA, James J, Rosario BL, Bi W, Nebes RD, Saxton JA, Snitz BE, Aizenstein HA, Wolk DA, Dekosky ST, Mathis CA, Klunk WE.

J Neurosci. 2009 Nov 25;29(47):14770-8. doi: 10.1523/JNEUROSCI.3669-09.2009.

PMID:
19940172
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue.

Ni R, Gillberg PG, Bergfors A, Marutle A, Nordberg A.

Brain. 2013 Jul;136(Pt 7):2217-27. doi: 10.1093/brain/awt142. Epub 2013 Jun 11.

PMID:
23757761
[PubMed - indexed for MEDLINE]
Free Article
5.

Correspondence between in vivo (11)C-PiB-PET amyloid imaging and postmortem, region-matched assessment of plaques.

Driscoll I, Troncoso JC, Rudow G, Sojkova J, Pletnikova O, Zhou Y, Kraut MA, Ferrucci L, Mathis CA, Klunk WE, O'Brien RJ, Davatzikos C, Wong DF, Resnick SM.

Acta Neuropathol. 2012 Dec;124(6):823-31. doi: 10.1007/s00401-012-1025-1. Epub 2012 Aug 5.

PMID:
22864813
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG.

Carter SF, Schöll M, Almkvist O, Wall A, Engler H, Långström B, Nordberg A.

J Nucl Med. 2012 Jan;53(1):37-46. doi: 10.2967/jnumed.110.087031.

PMID:
22213821
[PubMed - indexed for MEDLINE]
Free Article
7.

Different β-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity.

Bao F, Wicklund L, Lacor PN, Klein WL, Nordberg A, Marutle A.

Neurobiol Aging. 2012 Apr;33(4):825.e1-13. doi: 10.1016/j.neurobiolaging.2011.05.003. Epub 2011 Jun 17.

PMID:
21683475
[PubMed - indexed for MEDLINE]
8.

Resilience of Precuneus Neurotrophic Signaling Pathways Despite Amyloid Pathology in Prodromal Alzheimer's Disease.

Perez SE, He B, Nadeem M, Wuu J, Scheff SW, Abrahamson EE, Ikonomovic MD, Mufson EJ.

Biol Psychiatry. 2014 Jan 11. pii: S0006-3223(14)00012-2. doi: 10.1016/j.biopsych.2013.12.016. [Epub ahead of print]

PMID:
24529280
[PubMed - as supplied by publisher]
9.

Postmortem Pittsburgh Compound B (PiB) binding increases with Alzheimer's disease progression.

Beckett TL, Webb RL, Niedowicz DM, Holler CJ, Matveev S, Baig I, LeVine H 3rd, Keller JN, Murphy MP.

J Alzheimers Dis. 2012;32(1):127-38.

PMID:
22766739
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Deficient high-affinity binding of Pittsburgh compound B in a case of Alzheimer's disease.

Rosen RF, Ciliax BJ, Wingo TS, Gearing M, Dooyema J, Lah JJ, Ghiso JA, LeVine H 3rd, Walker LC.

Acta Neuropathol. 2010 Feb;119(2):221-33. doi: 10.1007/s00401-009-0583-3. Epub 2009 Aug 19.

PMID:
19690877
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

[(11)C]PIB-amyloid binding and levels of Abeta40 and Abeta42 in postmortem brain tissue from Alzheimer patients.

Svedberg MM, Hall H, Hellström-Lindahl E, Estrada S, Guan Z, Nordberg A, Långström B.

Neurochem Int. 2009 May-Jun;54(5-6):347-57. doi: 10.1016/j.neuint.2008.12.016. Epub 2008 Dec 30.

PMID:
19162107
[PubMed - indexed for MEDLINE]
12.

Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology.

Ikonomovic MD, Mufson EJ, Wuu J, Cochran EJ, Bennett DA, DeKosky ST.

J Alzheimers Dis. 2003 Feb;5(1):39-48.

PMID:
12590165
[PubMed - indexed for MEDLINE]
13.

PET amyloid ligand [11C]PIB uptake and cerebrospinal fluid beta-amyloid in mild cognitive impairment.

Koivunen J, Pirttilä T, Kemppainen N, Aalto S, Herukka SK, Jauhianen AM, Hänninen T, Hallikainen M, Någren K, Rinne JO, Soininen H.

Dement Geriatr Cogn Disord. 2008;26(4):378-83. doi: 10.1159/000163927. Epub 2008 Oct 16.

PMID:
18931497
[PubMed - indexed for MEDLINE]
14.

Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid.

Grimmer T, Riemenschneider M, Förstl H, Henriksen G, Klunk WE, Mathis CA, Shiga T, Wester HJ, Kurz A, Drzezga A.

Biol Psychiatry. 2009 Jun 1;65(11):927-34. doi: 10.1016/j.biopsych.2009.01.027. Epub 2009 Mar 6.

PMID:
19268916
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The decline in synapses and cholinergic activity is asynchronous in Alzheimer's disease.

Tiraboschi P, Hansen LA, Alford M, Masliah E, Thal LJ, Corey-Bloom J.

Neurology. 2000 Nov 14;55(9):1278-83.

PMID:
11087768
[PubMed - indexed for MEDLINE]
16.

Plasma Aβ and PET PiB binding are inversely related in mild cognitive impairment.

Devanand DP, Schupf N, Stern Y, Parsey R, Pelton GH, Mehta P, Mayeux R.

Neurology. 2011 Jul 12;77(2):125-31. doi: 10.1212/WNL.0b013e318224afb7. Epub 2011 Jun 29.

PMID:
21715709
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease.

Mufson EJ, He B, Nadeem M, Perez SE, Counts SE, Leurgans S, Fritz J, Lah J, Ginsberg SD, Wuu J, Scheff SW.

J Neuropathol Exp Neurol. 2012 Nov;71(11):1018-29. doi: 10.1097/NEN.0b013e318272caab.

PMID:
23095849
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study.

Villemagne VL, Burnham S, Bourgeat P, Brown B, Ellis KA, Salvado O, Szoeke C, Macaulay SL, Martins R, Maruff P, Ames D, Rowe CC, Masters CL; Australian Imaging Biomarkers and Lifestyle (AIBL) Research Group.

Lancet Neurol. 2013 Apr;12(4):357-67. doi: 10.1016/S1474-4422(13)70044-9. Epub 2013 Mar 8.

PMID:
23477989
[PubMed - indexed for MEDLINE]
19.

Amyloid is linked to cognitive decline in patients with Parkinson disease without dementia.

Gomperts SN, Locascio JJ, Rentz D, Santarlasci A, Marquie M, Johnson KA, Growdon JH.

Neurology. 2013 Jan 1;80(1):85-91. doi: 10.1212/WNL.0b013e31827b1a07. Epub 2012 Dec 12.

PMID:
23243071
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Quantitative longitudinal interrelationships between brain metabolism and amyloid deposition during a 2-year follow-up in patients with early Alzheimer's disease.

Förster S, Yousefi BH, Wester HJ, Klupp E, Rominger A, Förstl H, Kurz A, Grimmer T, Drzezga A.

Eur J Nucl Med Mol Imaging. 2012 Dec;39(12):1927-36. doi: 10.1007/s00259-012-2230-9. Epub 2012 Aug 28.

PMID:
22926714
[PubMed - indexed for MEDLINE]

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