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Downregulation of Filamin A interacting protein 1-like is associated with promoter methylation and induces an invasive phenotype in ovarian cancer.

Burton ER, Gaffar A, Lee SJ, Adeshuko F, Whitney KD, Chung JY, Hewitt SM, Huang GS, Goldberg GL, Libutti SK, Kwon M.

Mol Cancer Res. 2011 Aug;9(8):1126-38. doi: 10.1158/1541-7786.MCR-11-0162. Epub 2011 Jun 21.


Down-regulation of Filamin A interacting protein 1-like Is associated with promoter methylation and an invasive phenotype in breast, colon, lung and pancreatic cancers [corrected].

Kwon M, Lee SJ, Reddy S, Rybak Y, Adem A, Libutti SK.

PLoS One. 2013 Dec 5;8(12):e82620. doi: 10.1371/journal.pone.0082620. eCollection 2013. Erratum in: PLoS One. 2013;8(12). doi:10.1371/annotation/b2ee22c9-aa14-4c03-861c-b37f1a842bcd.


Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis.

Kwon M, Lee SJ, Wang Y, Rybak Y, Luna A, Reddy S, Adem A, Beaty BT, Condeelis JS, Libutti SK.

Int J Cancer. 2014 Jul 1;135(1):48-60. doi: 10.1002/ijc.28662. Epub 2014 Feb 20.


CpG island hypermethylation frequently silences FILIP1L isoform 2 expression in prostate cancer.

Desotelle J, Truong M, Ewald J, Weeratunga P, Yang B, Huang W, Jarrard D.

J Urol. 2013 Jan;189(1):329-35. doi: 10.1016/j.juro.2012.08.188. Epub 2012 Nov 20.


Sensitivity to TOP2 targeting chemotherapeutics is regulated by Oct1 and FILIP1L.

Lu H, Hallstrom TC.

PLoS One. 2012;7(8):e42921. doi: 10.1371/journal.pone.0042921. Epub 2012 Aug 10.


STAT3 acetylation-induced promoter methylation is associated with downregulation of the ARHI tumor-suppressor gene in ovarian cancer.

Li J, Cui G, Sun L, Wang SJ, Li YL, Meng YG, Guan Z, Fan WS, Li LA, Yang YZ, You YQ, Fu XY, Yan ZF, Huang K.

Oncol Rep. 2013 Jul;30(1):165-70. doi: 10.3892/or.2013.2414. Epub 2013 Apr 22.


Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.

Yuan J, Luo RZ, Fujii S, Wang L, Hu W, Andreeff M, Pan Y, Kadota M, Oshimura M, Sahin AA, Issa JP, Bast RC Jr, Yu Y.

Cancer Res. 2003 Jul 15;63(14):4174-80.


Analysis of promoter non-CG methylation in prostate cancer.

Truong M, Yang B, Wagner J, Desotelle J, Jarrard DF.

Epigenomics. 2013 Feb;5(1):65-71. doi: 10.2217/epi.12.67.


Promoter hypermethylation contributes to frequent inactivation of a putative conditional tumor suppressor gene connective tissue growth factor in ovarian cancer.

Kikuchi R, Tsuda H, Kanai Y, Kasamatsu T, Sengoku K, Hirohashi S, Inazawa J, Imoto I.

Cancer Res. 2007 Aug 1;67(15):7095-105.


Demethylation of the MCJ gene in stage III/IV epithelial ovarian cancer and response to chemotherapy.

Strathdee G, Vass JK, Oien KA, Siddiqui N, Curto-Garcia J, Brown R.

Gynecol Oncol. 2005 Jun;97(3):898-903.


Promoter methylation status and expression of TMS1 gene in human epithelial ovarian cancer.

Akahira J, Sugihashi Y, Ito K, Niikura H, Okamura K, Yaegashi N.

Cancer Sci. 2004 Jan;95(1):40-3.


Homo sapiens lactate dehydrogenase c (Ldhc) gene expression in cancer cells is regulated by transcription factor Sp1, CREB, and CpG island methylation.

Tang H, Goldberg E.

J Androl. 2009 Mar-Apr;30(2):157-67. doi: 10.2164/jandrol.108.005785. Epub 2008 Oct 16.


Frequent inactivation of a putative tumor suppressor, angiopoietin-like protein 2, in ovarian cancer.

Kikuchi R, Tsuda H, Kozaki K, Kanai Y, Kasamatsu T, Sengoku K, Hirohashi S, Inazawa J, Imoto I.

Cancer Res. 2008 Jul 1;68(13):5067-75. doi: 10.1158/0008-5472.CAN-08-0062.


Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene.

Strathdee G, Davies BR, Vass JK, Siddiqui N, Brown R.

Carcinogenesis. 2004 May;25(5):693-701. Epub 2004 Jan 16.


DNA promoter methylation-dependent transcription of the double C2-like domain β (DOC2B) gene regulates tumor growth in human cervical cancer.

Kabekkodu SP, Bhat S, Radhakrishnan R, Aithal A, Mascarenhas R, Pandey D, Rai L, Kushtagi P, Mundyat GP, Satyamoorthy K.

J Biol Chem. 2014 Apr 11;289(15):10637-49. doi: 10.1074/jbc.M113.491506. Epub 2014 Feb 25.


Decreased expression of 14-3-3 sigma is associated with advanced disease in human epithelial ovarian cancer: its correlation with aberrant DNA methylation.

Akahira J, Sugihashi Y, Suzuki T, Ito K, Niikura H, Moriya T, Nitta M, Okamura H, Inoue S, Sasano H, Okamura K, Yaegashi N.

Clin Cancer Res. 2004 Apr 15;10(8):2687-93.


Promoter hypermethylation of FANCF plays an important role in the occurrence of ovarian cancer through disrupting Fanconi anemia-BRCA pathway.

Wang Z, Li M, Lu S, Zhang Y, Wang H.

Cancer Biol Ther. 2006 Mar;5(3):256-60. Epub 2006 Mar 5.


OASIS/CREB3L1 is epigenetically silenced in human bladder cancer facilitating tumor cell spreading and migration in vitro.

Rose M, Schubert C, Dierichs L, Gaisa NT, Heer M, Heidenreich A, Knüchel R, Dahl E.

Epigenetics. 2014 Dec;9(12):1626-40. doi: 10.4161/15592294.2014.988052.

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