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Results: 1 to 20 of 118

1.

A targeted proteomics-based pipeline for verification of biomarkers in plasma.

Whiteaker JR, Lin C, Kennedy J, Hou L, Trute M, Sokal I, Yan P, Schoenherr RM, Zhao L, Voytovich UJ, Kelly-Spratt KS, Krasnoselsky A, Gafken PR, Hogan JM, Jones LA, Wang P, Amon L, Chodosh LA, Nelson PS, McIntosh MW, Kemp CJ, Paulovich AG.

Nat Biotechnol. 2011 Jun 19;29(7):625-34. doi: 10.1038/nbt.1900.

PMID:
21685906
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Streamlining biomarker discovery.

Latterich M, Schnitzer JE.

Nat Biotechnol. 2011 Jul 11;29(7):600-2. doi: 10.1038/nbt.1917. No abstract available.

PMID:
21747385
[PubMed - indexed for MEDLINE]
3.

A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease.

Addona TA, Shi X, Keshishian H, Mani DR, Burgess M, Gillette MA, Clauser KR, Shen D, Lewis GD, Farrell LA, Fifer MA, Sabatine MS, Gerszten RE, Carr SA.

Nat Biotechnol. 2011 Jun 19;29(7):635-43. doi: 10.1038/nbt.1899.

PMID:
21685905
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Identification of multiple novel protein biomarkers shed by human serous ovarian tumors into the blood of immunocompromised mice and verified in patient sera.

Beer LA, Wang H, Tang HY, Cao Z, Chang-Wong T, Tanyi JL, Zhang R, Liu Q, Speicher DW.

PLoS One. 2013;8(3):e60129. doi: 10.1371/journal.pone.0060129. Epub 2013 Mar 27.

PMID:
23544127
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A xenograft mouse model coupled with in-depth plasma proteome analysis facilitates identification of novel serum biomarkers for human ovarian cancer.

Tang HY, Beer LA, Chang-Wong T, Hammond R, Gimotty P, Coukos G, Speicher DW.

J Proteome Res. 2012 Feb 3;11(2):678-91. doi: 10.1021/pr200603h. Epub 2011 Nov 18.

PMID:
22032327
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Protein biomarker discovery and validation: the long and uncertain path to clinical utility.

Rifai N, Gillette MA, Carr SA.

Nat Biotechnol. 2006 Aug;24(8):971-83. Review.

PMID:
16900146
[PubMed - indexed for MEDLINE]
7.

Prioritization of candidate protein biomarkers from an in vitro model system of breast tumor progression toward clinical verification.

Lau TY, Power KA, Dijon S, de Gardelle I, McDonnell S, Duffy MJ, Pennington SR, Gallagher WM.

J Proteome Res. 2010 Mar 5;9(3):1450-9. doi: 10.1021/pr900989q.

PMID:
20000743
[PubMed - indexed for MEDLINE]
8.

Multiplexed MRM-based quantitation of candidate cancer biomarker proteins in undepleted and non-enriched human plasma.

Percy AJ, Chambers AG, Yang J, Borchers CH.

Proteomics. 2013 Jul;13(14):2202-15. doi: 10.1002/pmic.201200316. Epub 2013 Jun 6.

PMID:
23592487
[PubMed - indexed for MEDLINE]
9.

Integrated pipeline for mass spectrometry-based discovery and confirmation of biomarkers demonstrated in a mouse model of breast cancer.

Whiteaker JR, Zhang H, Zhao L, Wang P, Kelly-Spratt KS, Ivey RG, Piening BD, Feng LC, Kasarda E, Gurley KE, Eng JK, Chodosh LA, Kemp CJ, McIntosh MW, Paulovich AG.

J Proteome Res. 2007 Oct;6(10):3962-75. Epub 2007 Aug 21.

PMID:
17711321
[PubMed - indexed for MEDLINE]
10.

The bottleneck in the cancer biomarker pipeline and protein quantification through mass spectrometry-based approaches: current strategies for candidate verification.

Makawita S, Diamandis EP.

Clin Chem. 2010 Feb;56(2):212-22. doi: 10.1373/clinchem.2009.127019. Epub 2009 Dec 10. Review.

PMID:
20007861
[PubMed - indexed for MEDLINE]
Free Article
11.

A lectin-coupled, targeted proteomic mass spectrometry (MRM MS) platform for identification of multiple liver cancer biomarkers in human plasma.

Ahn YH, Shin PM, Oh NR, Park GW, Kim H, Yoo JS.

J Proteomics. 2012 Sep 18;75(17):5507-15. doi: 10.1016/j.jprot.2012.06.027. Epub 2012 Jul 10.

PMID:
22789673
[PubMed - indexed for MEDLINE]
12.

Mass spectrometry-based expression profiling of clinical prostate cancer.

Wright ME, Han DK, Aebersold R.

Mol Cell Proteomics. 2005 Apr;4(4):545-54. Epub 2005 Feb 2. Review.

PMID:
15695425
[PubMed - indexed for MEDLINE]
Free Article
13.

Identification of tumor-associated plasma biomarkers using proteomic techniques: from mouse to human.

Juan HF, Chen JH, Hsu WT, Huang SC, Chen ST, Yi-Chung Lin J, Chang YW, Chiang CY, Wen LL, Chan DC, Liu YC, Chen YJ.

Proteomics. 2004 Sep;4(9):2766-75.

PMID:
15352250
[PubMed - indexed for MEDLINE]
14.

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma.

Addona TA, Abbatiello SE, Schilling B, Skates SJ, Mani DR, Bunk DM, Spiegelman CH, Zimmerman LJ, Ham AJ, Keshishian H, Hall SC, Allen S, Blackman RK, Borchers CH, Buck C, Cardasis HL, Cusack MP, Dodder NG, Gibson BW, Held JM, Hiltke T, Jackson A, Johansen EB, Kinsinger CR, Li J, Mesri M, Neubert TA, Niles RK, Pulsipher TC, Ransohoff D, Rodriguez H, Rudnick PA, Smith D, Tabb DL, Tegeler TJ, Variyath AM, Vega-Montoto LJ, Wahlander A, Waldemarson S, Wang M, Whiteaker JR, Zhao L, Anderson NL, Fisher SJ, Liebler DC, Paulovich AG, Regnier FE, Tempst P, Carr SA.

Nat Biotechnol. 2009 Jul;27(7):633-41. doi: 10.1038/nbt.1546. Epub 2009 Jun 28. Erratum in: Nat Biotechnol. 2009 Sep;27(9):864.

PMID:
19561596
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Targeted mass spectrometry approaches for protein biomarker verification.

Meng Z, Veenstra TD.

J Proteomics. 2011 Nov 18;74(12):2650-9. doi: 10.1016/j.jprot.2011.04.011. Epub 2011 Apr 21. Review.

PMID:
21540133
[PubMed - indexed for MEDLINE]
16.

Computational biomarker pipeline from discovery to clinical implementation: plasma proteomic biomarkers for cardiac transplantation.

Cohen Freue GV, Meredith A, Smith D, Bergman A, Sasaki M, Lam KK, Hollander Z, Opushneva N, Takhar M, Lin D, Wilson-McManus J, Balshaw R, Keown PA, Borchers CH, McManus B, Ng RT, McMaster WR; Biomarkers in Transplantation and the NCE CECR Prevention of Organ Failure Centre of Excellence Teams.

PLoS Comput Biol. 2013 Apr;9(4):e1002963. doi: 10.1371/journal.pcbi.1002963. Epub 2013 Apr 4.

PMID:
23592955
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Development of a pharmaceutical hepatotoxicity biomarker panel using a discovery to targeted proteomics approach.

Collins BC, Miller CA, Sposny A, Hewitt P, Wells M, Gallagher WM, Pennington SR.

Mol Cell Proteomics. 2012 Aug;11(8):394-410. doi: 10.1074/mcp.M111.016493. Epub 2012 Apr 23.

PMID:
22527513
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Perspectives of targeted mass spectrometry for protein biomarker verification.

Hüttenhain R, Malmström J, Picotti P, Aebersold R.

Curr Opin Chem Biol. 2009 Dec;13(5-6):518-25. doi: 10.1016/j.cbpa.2009.09.014. Epub 2009 Oct 7. Review.

PMID:
19818677
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer.

Tang HY, Beer LA, Tanyi JL, Zhang R, Liu Q, Speicher DW.

J Proteomics. 2013 Aug 26;89:165-78. doi: 10.1016/j.jprot.2013.06.016. Epub 2013 Jun 21.

PMID:
23792823
[PubMed - indexed for MEDLINE]
20.

Mass spectrometric characterization of protein structure details refines the proteome signature for invasive ductal breast carcinoma.

Röwer C, Koy C, Hecker M, Reimer T, Gerber B, Thiesen HJ, Glocker MO.

J Am Soc Mass Spectrom. 2011 Mar;22(3):440-56. doi: 10.1007/s13361-010-0031-6. Epub 2011 Feb 8.

PMID:
21472563
[PubMed - indexed for MEDLINE]

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