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Results: 1 to 20 of 134

1.

Outbred ICR/CD1 mice display more severe neuroinflammation mediated by microglial TLR4/CD14 activation than inbred C57Bl/6 mice.

Nikodemova M, Watters JJ.

Neuroscience. 2011 Sep 8;190:67-74. doi: 10.1016/j.neuroscience.2011.06.006. Epub 2011 Jun 13.

PMID:
21683771
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide.

Zhou H, Lapointe BM, Clark SR, Zbytnuik L, Kubes P.

J Immunol. 2006 Dec 1;177(11):8103-10.

PMID:
17114485
[PubMed - indexed for MEDLINE]
Free Article
3.

GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia.

Parajuli B, Sonobe Y, Kawanokuchi J, Doi Y, Noda M, Takeuchi H, Mizuno T, Suzumura A.

J Neuroinflammation. 2012 Dec 13;9:268. doi: 10.1186/1742-2094-9-268.

PMID:
23234315
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Peripheral innate immune challenge exaggerated microglia activation, increased the number of inflammatory CNS macrophages, and prolonged social withdrawal in socially defeated mice.

Wohleb ES, Fenn AM, Pacenta AM, Powell ND, Sheridan JF, Godbout JP.

Psychoneuroendocrinology. 2012 Sep;37(9):1491-505. doi: 10.1016/j.psyneuen.2012.02.003. Epub 2012 Mar 2.

PMID:
22386198
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines.

Henry CJ, Huang Y, Wynne AM, Godbout JP.

Brain Behav Immun. 2009 Mar;23(3):309-17. doi: 10.1016/j.bbi.2008.09.002. Epub 2008 Sep 12.

PMID:
18814846
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Absence of CD14 delays progression of prion diseases accompanied by increased microglial activation.

Sakai K, Hasebe R, Takahashi Y, Song CH, Suzuki A, Yamasaki T, Horiuchi M.

J Virol. 2013 Dec;87(24):13433-45. doi: 10.1128/JVI.02072-13. Epub 2013 Oct 2.

PMID:
24089559
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia.

Yao L, Kan EM, Lu J, Hao A, Dheen ST, Kaur C, Ling EA.

J Neuroinflammation. 2013 Feb 6;10:23. doi: 10.1186/1742-2094-10-23.

PMID:
23388509
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Protosappanin A inhibits oxidative and nitrative stress via interfering the interaction of transmembrane protein CD14 with Toll-like receptor-4 in lipopolysaccharide-induced BV-2 microglia.

Zeng KW, Zhao MB, Ma ZZ, Jiang Y, Tu PF.

Int Immunopharmacol. 2012 Dec;14(4):558-69. doi: 10.1016/j.intimp.2012.09.004. Epub 2012 Sep 21.

PMID:
23000519
[PubMed - indexed for MEDLINE]
9.

Chronic intermittent hypoxia exerts CNS region-specific effects on rat microglial inflammatory and TLR4 gene expression.

Smith SM, Friedle SA, Watters JJ.

PLoS One. 2013 Dec 4;8(12):e81584. doi: 10.1371/journal.pone.0081584. eCollection 2013.

PMID:
24324707
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway.

Pais TF, Figueiredo C, Peixoto R, Braz MH, Chatterjee S.

J Neuroinflammation. 2008 Oct 9;5:43. doi: 10.1186/1742-2094-5-43.

PMID:
18844999
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Efficient isolation of live microglia with preserved phenotypes from adult mouse brain.

Nikodemova M, Watters JJ.

J Neuroinflammation. 2012 Jun 28;9:147. doi: 10.1186/1742-2094-9-147.

PMID:
22742584
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker.

Jung DY, Lee H, Jung BY, Ock J, Lee MS, Lee WH, Suk K.

J Immunol. 2005 May 15;174(10):6467-76.

PMID:
15879150
[PubMed - indexed for MEDLINE]
Free Article
13.

Distinct roles of pattern recognition receptors CD14 and Toll-like receptor 4 in acute lung injury.

Jeyaseelan S, Chu HW, Young SK, Freeman MW, Worthen GS.

Infect Immun. 2005 Mar;73(3):1754-63.

PMID:
15731076
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Microglial CD14 activated by iNOS contributes to neuroinflammation in cerebral ischemia.

Zhou M, Wang CM, Yang WL, Wang P.

Brain Res. 2013 Apr 19;1506:105-14. doi: 10.1016/j.brainres.2013.02.010. Epub 2013 Feb 14.

PMID:
23416151
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity.

Shi J, Johansson J, Woodling NS, Wang Q, Montine TJ, Andreasson K.

J Immunol. 2010 Jun 15;184(12):7207-18. doi: 10.4049/jimmunol.0903487. Epub 2010 May 7.

PMID:
20483760
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia.

Gomes C, Ferreira R, George J, Sanches R, Rodrigues DI, Gonçalves N, Cunha RA.

J Neuroinflammation. 2013 Jan 30;10:16. doi: 10.1186/1742-2094-10-16.

PMID:
23363775
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Neuroprotective effects of pretreatment with propofol in LPS-induced BV-2 microglia cells: role of TLR4 and GSK-3β.

Gui B, Su M, Chen J, Jin L, Wan R, Qian Y.

Inflammation. 2012 Oct;35(5):1632-40. doi: 10.1007/s10753-012-9478-x.

PMID:
22588329
[PubMed - indexed for MEDLINE]
18.

β-Adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat.

Wohleb ES, Hanke ML, Corona AW, Powell ND, Stiner LM, Bailey MT, Nelson RJ, Godbout JP, Sheridan JF.

J Neurosci. 2011 Apr 27;31(17):6277-88. doi: 10.1523/JNEUROSCI.0450-11.2011.

PMID:
21525267
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS.

Regen T, van Rossum D, Scheffel J, Kastriti ME, Revelo NH, Prinz M, Brück W, Hanisch UK.

Brain Behav Immun. 2011 Jul;25(5):957-70. doi: 10.1016/j.bbi.2010.10.009. Epub 2010 Oct 15.

PMID:
20951794
[PubMed - indexed for MEDLINE]
20.

Central effects of a local inflammation in three commonly used mouse strains with a different anxious phenotype.

Benatti C, Alboni S, Montanari C, Caggia F, Tascedda F, Brunello N, Blom JM.

Behav Brain Res. 2011 Oct 10;224(1):23-34. doi: 10.1016/j.bbr.2011.05.011. Epub 2011 May 23.

PMID:
21624397
[PubMed - indexed for MEDLINE]
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