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Results: 1 to 20 of 82

1.

Transmigration of beta amyloid specific heavy chain antibody fragments across the in vitro blood-brain barrier.

Rutgers KS, Nabuurs RJ, van den Berg SA, Schenk GJ, Rotman M, Verrips CT, van Duinen SG, Maat-Schieman ML, van Buchem MA, de Boer AG, van der Maarel SM.

Neuroscience. 2011 Sep 8;190:37-42. doi: 10.1016/j.neuroscience.2011.05.076. Epub 2011 Jun 13.

PMID:
21683126
[PubMed - indexed for MEDLINE]
2.

In vivo detection of amyloid-β deposits using heavy chain antibody fragments in a transgenic mouse model for Alzheimer's disease.

Nabuurs RJ, Rutgers KS, Welling MM, Metaxas A, de Backer ME, Rotman M, Bacskai BJ, van Buchem MA, van der Maarel SM, van der Weerd L.

PLoS One. 2012;7(6):e38284. doi: 10.1371/journal.pone.0038284. Epub 2012 Jun 4.

PMID:
22675537
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Epitope-dependent effects of Beta-amyloid antibodies on Beta-amyloid clearance in an in vitro model of the blood-brain barrier.

Bachmeier CJ, Beaulieu-Abdelahad D, Mullan MJ, Paris D.

Microcirculation. 2011 Jul;18(5):373-9. doi: 10.1111/j.1549-8719.2011.00096.x.

PMID:
21418385
[PubMed - indexed for MEDLINE]
4.

Fusion antibody for Alzheimer's disease with bidirectional transport across the blood-brain barrier and abeta fibril disaggregation.

Boado RJ, Zhang Y, Zhang Y, Xia CF, Pardridge WM.

Bioconjug Chem. 2007 Mar-Apr;18(2):447-55. Epub 2007 Feb 22.

PMID:
17315944
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The role of the ATP-binding cassette transporter P-glycoprotein in the transport of β-amyloid across the blood-brain barrier.

Vogelgesang S, Jedlitschky G, Brenn A, Walker LC.

Curr Pharm Des. 2011;17(26):2778-86. Review.

PMID:
21827406
[PubMed - indexed for MEDLINE]
6.
7.

Circulating amyloid-beta peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions.

Mackic JB, Bading J, Ghiso J, Walker L, Wisniewski T, Frangione B, Zlokovic BV.

Vascul Pharmacol. 2002 Jun;38(6):303-13.

PMID:
12529925
[PubMed - indexed for MEDLINE]
8.

Design and evaluation of a 6-mer amyloid-beta protein derived phage display library for molecular targeting of amyloid plaques in Alzheimer's disease: Comparison with two cyclic heptapeptides derived from a randomized phage display library.

Larbanoix L, Burtea C, Ansciaux E, Laurent S, Mahieu I, Vander Elst L, Muller RN.

Peptides. 2011 Jun;32(6):1232-43. doi: 10.1016/j.peptides.2011.04.026. Epub 2011 May 6.

PMID:
21575663
[PubMed - indexed for MEDLINE]
9.

Blood-brain-barrier models for the investigation of transporter- and receptor-mediated amyloid-β clearance in Alzheimer's disease.

Pflanzner T, Kuhlmann CR, Pietrzik CU.

Curr Alzheimer Res. 2010 Nov;7(7):578-90. Review.

PMID:
20704558
[PubMed - indexed for MEDLINE]
10.
11.

Differential recognition of vascular and parenchymal beta amyloid deposition.

Rutgers KS, van Remoortere A, van Buchem MA, Verrips CT, Greenberg SM, Bacskai BJ, Frosch MP, van Duinen SG, Maat-Schieman ML, van der Maarel SM.

Neurobiol Aging. 2011 Oct;32(10):1774-83. doi: 10.1016/j.neurobiolaging.2009.11.012. Epub 2009 Dec 16.

PMID:
20015576
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

In vivo targeting of antibody fragments to the nervous system for Alzheimer's disease immunotherapy and molecular imaging of amyloid plaques.

Poduslo JF, Ramakrishnan M, Holasek SS, Ramirez-Alvarado M, Kandimalla KK, Gilles EJ, Curran GL, Wengenack TM.

J Neurochem. 2007 Jul;102(2):420-33.

PMID:
17596213
[PubMed - indexed for MEDLINE]
13.

Quinoline-n-butylcyanoacrylate-based nanoparticles for brain targeting for the diagnosis of Alzheimer's disease.

Kulkarni PV, Roney CA, Antich PP, Bonte FJ, Raghu AV, Aminabhavi TM.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 Jan-Feb;2(1):35-47. doi: 10.1002/wnan.59. Review.

PMID:
20049829
[PubMed - indexed for MEDLINE]
14.

Chitosan enhances the stability and targeting of immuno-nanovehicles to cerebro-vascular deposits of Alzheimer's disease amyloid protein.

Jaruszewski KM, Ramakrishnan S, Poduslo JF, Kandimalla KK.

Nanomedicine. 2012 Feb;8(2):250-60. doi: 10.1016/j.nano.2011.06.008. Epub 2011 Jun 24.

PMID:
21704598
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

[Role of the blood-brain barrier in Alzheimer's disease].

Gosselet F, Candela P, Cecchelli R, Fenart L.

Med Sci (Paris). 2011 Nov;27(11):987-92. doi: 10.1051/medsci/20112711015. Epub 2011 Nov 30. Review. French.

PMID:
22130026
[PubMed - indexed for MEDLINE]
Free Article
16.

Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging.

Li T, Bourgeois JP, Celli S, Glacial F, Le Sourd AM, Mecheri S, Weksler B, Romero I, Couraud PO, Rougeon F, Lafaye P.

FASEB J. 2012 Oct;26(10):3969-79. doi: 10.1096/fj.11-201384. Epub 2012 Jun 22.

PMID:
22730440
[PubMed - indexed for MEDLINE]
Free Article
17.

[Characterization of amyloid beta protein species in the plasma, cerebrospinal fluid and brains of patients with Alzheimer's disease].

Tamaoka A.

Nihon Ronen Igakkai Zasshi. 1998 Apr;35(4):273-7. Japanese.

PMID:
9643008
[PubMed - indexed for MEDLINE]
Free Article
18.

The blood-brain barrier in Alzheimer's disease: novel therapeutic targets and nanodrug delivery.

Sharma HS, Castellani RJ, Smith MA, Sharma A.

Int Rev Neurobiol. 2012;102:47-90. doi: 10.1016/B978-0-12-386986-9.00003-X. Review.

PMID:
22748826
[PubMed - indexed for MEDLINE]
19.

Pharmacokinetic analysis of the blood-brain barrier transport of 125I-amyloid beta protein 40 in wild-type and Alzheimer's disease transgenic mice (APP,PS1) and its implications for amyloid plaque formation.

Kandimalla KK, Curran GL, Holasek SS, Gilles EJ, Wengenack TM, Poduslo JF.

J Pharmacol Exp Ther. 2005 Jun;313(3):1370-8. Epub 2005 Mar 2.

PMID:
15743932
[PubMed - indexed for MEDLINE]
Free Article
20.

Method for measurement of the blood-brain barrier permeability in the perfused mouse brain: application to amyloid-beta peptide in wild type and Alzheimer's Tg2576 mice.

LaRue B, Hogg E, Sagare A, Jovanovic S, Maness L, Maurer C, Deane R, Zlokovic BV.

J Neurosci Methods. 2004 Sep 30;138(1-2):233-42.

PMID:
15325132
[PubMed - indexed for MEDLINE]

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