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Results: 1 to 20 of 106

1.

Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation.

Sievers SA, Karanicolas J, Chang HW, Zhao A, Jiang L, Zirafi O, Stevens JT, Münch J, Baker D, Eisenberg D.

Nature. 2011 Jun 15;475(7354):96-100. doi: 10.1038/nature10154.

PMID:
21677644
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Understanding amyloid fibril nucleation and aβ oligomer/drug interactions from computer simulations.

Nguyen P, Derreumaux P.

Acc Chem Res. 2014 Feb 18;47(2):603-11. doi: 10.1021/ar4002075. Epub 2013 Dec 24. Review.

PMID:
24368046
[PubMed - indexed for MEDLINE]
3.

Structure and intermolecular dynamics of aggregates populated during amyloid fibril formation studied by hydrogen/deuterium exchange.

Carulla N, Zhou M, Giralt E, Robinson CV, Dobson CM.

Acc Chem Res. 2010 Aug 17;43(8):1072-9. doi: 10.1021/ar9002784.

PMID:
20557067
[PubMed - indexed for MEDLINE]
4.

Role of water in protein aggregation and amyloid polymorphism.

Thirumalai D, Reddy G, Straub JE.

Acc Chem Res. 2012 Jan 17;45(1):83-92. doi: 10.1021/ar2000869. Epub 2011 Jul 15.

PMID:
21761818
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Polymorphic fibril formation by residues 10-40 of the Alzheimer's beta-amyloid peptide.

Paravastu AK, Petkova AT, Tycko R.

Biophys J. 2006 Jun 15;90(12):4618-29. Epub 2006 Mar 24.

PMID:
16565054
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Atomic structures of amyloid cross-beta spines reveal varied steric zippers.

Sawaya MR, Sambashivan S, Nelson R, Ivanova MI, Sievers SA, Apostol MI, Thompson MJ, Balbirnie M, Wiltzius JJ, McFarlane HT, Madsen AØ, Riekel C, Eisenberg D.

Nature. 2007 May 24;447(7143):453-7. Epub 2007 Apr 29.

PMID:
17468747
[PubMed - indexed for MEDLINE]
7.

Protein denaturation and aggregation: Cellular responses to denatured and aggregated proteins.

Meredith SC.

Ann N Y Acad Sci. 2005 Dec;1066:181-221. Review.

PMID:
16533927
[PubMed - indexed for MEDLINE]
8.

Molecular determinants for amyloid fibril formation: lessons from lung surfactant protein C.

Johansson J.

Swiss Med Wkly. 2003 May 17;133(19-20):275-82. Review.

PMID:
12844270
[PubMed - indexed for MEDLINE]
Free Article
9.

Amyloid-forming propensity of the hydrophobic non-natural amino acid on the fibril-forming core peptide of human tau.

Hirata A, Sugimoto K, Konno T, Morii T.

Bioorg Med Chem Lett. 2007 Jun 1;17(11):2971-4. Epub 2007 Mar 25.

PMID:
17416523
[PubMed - indexed for MEDLINE]
10.

Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

Sato T, Kienlen-Campard P, Ahmed M, Liu W, Li H, Elliott JI, Aimoto S, Constantinescu SN, Octave JN, Smith SO.

Biochemistry. 2006 May 2;45(17):5503-16.

PMID:
16634632
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

N-terminal domain of myelin basic protein inhibits amyloid beta-protein fibril assembly.

Liao MC, Hoos MD, Aucoin D, Ahmed M, Davis J, Smith SO, Van Nostrand WE.

J Biol Chem. 2010 Nov 12;285(46):35590-8. doi: 10.1074/jbc.M110.169599. Epub 2010 Aug 31.

PMID:
20807757
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

What drives amyloid molecules to assemble into oligomers and fibrils?

Schmit JD, Ghosh K, Dill K.

Biophys J. 2011 Jan 19;100(2):450-8. doi: 10.1016/j.bpj.2010.11.041.

PMID:
21244841
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Amyloid-like fibril formation by polyQ proteins: a critical balance between the polyQ length and the constraints imposed by the host protein.

Scarafone N, Pain C, Fratamico A, Gaspard G, Yilmaz N, Filée P, Galleni M, Matagne A, Dumoulin M.

PLoS One. 2012;7(3):e31253. doi: 10.1371/journal.pone.0031253. Epub 2012 Mar 9.

PMID:
22438863
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Switch-peptides: design and characterization of controllable super-amyloid-forming host-guest peptides as tools for identifying anti-amyloid agents.

Camus MS, Dos Santos S, Chandravarkar A, Mandal B, Schmid AW, Tuchscherer G, Mutter M, Lashuel HA.

Chembiochem. 2008 Sep 1;9(13):2104-12. doi: 10.1002/cbic.200800245.

PMID:
18683159
[PubMed - indexed for MEDLINE]
15.

Structural regulation of a peptide-conjugated graft copolymer: a simple model for amyloid formation.

Koga T, Taguchi K, Kobuke Y, Kinoshita T, Higuchi M.

Chemistry. 2003 Mar 3;9(5):1146-56.

PMID:
12596151
[PubMed - indexed for MEDLINE]
16.

Spatial separation of beta-sheet domains of beta-amyloid: disruption of each beta-sheet by N-methyl amino acids.

Sciarretta KL, Boire A, Gordon DJ, Meredith SC.

Biochemistry. 2006 Aug 8;45(31):9485-95.

PMID:
16878983
[PubMed - indexed for MEDLINE]
17.

Drastic effects on fibril formation of amyloid-beta peptides by the addition of amino acid residue units to the termini.

Asanomi Y, Kobayashi Y, Sakai H, Masuda T, Chen X, Chuman Y, Uosaki K, Sakaguchi K.

Protein Pept Lett. 2010 Apr;17(4):458-63.

PMID:
20044924
[PubMed - indexed for MEDLINE]
18.

Mechanisms of amyloid fibril self-assembly and inhibition. Model short peptides as a key research tool.

Gazit E.

FEBS J. 2005 Dec;272(23):5971-8. Review.

PMID:
16302962
[PubMed - indexed for MEDLINE]
Free Article
19.

Amyloid fibril formation from sequences of a natural beta-structured fibrous protein, the adenovirus fiber.

Papanikolopoulou K, Schoehn G, Forge V, Forsyth VT, Riekel C, Hernandez JF, Ruigrok RW, Mitraki A.

J Biol Chem. 2005 Jan 28;280(4):2481-90. Epub 2004 Oct 27.

PMID:
15513921
[PubMed - indexed for MEDLINE]
Free Article
20.

Plasticity of amyloid fibrils.

Wetzel R, Shivaprasad S, Williams AD.

Biochemistry. 2007 Jan 9;46(1):1-10. Review.

PMID:
17198370
[PubMed - indexed for MEDLINE]
Free PMC Article

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