Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 130

1.

Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases.

Choi YH, Suzuki A, Hajarnis S, Ma Z, Chapin HC, Caplan MJ, Pontoglio M, Somlo S, Igarashi P.

Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10679-84. doi: 10.1073/pnas.1016214108. Epub 2011 Jun 13.

2.

Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease.

Smith LA, Bukanov NO, Husson H, Russo RJ, Barry TC, Taylor AL, Beier DR, Ibraghimov-Beskrovnaya O.

J Am Soc Nephrol. 2006 Oct;17(10):2821-31. Epub 2006 Aug 23.

3.

Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells.

Li Q, Montalbetti N, Wu Y, Ramos A, Raychowdhury MK, Chen XZ, Cantiello HF.

J Biol Chem. 2006 Dec 8;281(49):37566-75. Epub 2006 Sep 1.

4.
5.

Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis.

Hiesberger T, Shao X, Gourley E, Reimann A, Pontoglio M, Igarashi P.

J Biol Chem. 2005 Mar 18;280(11):10578-86. Epub 2005 Jan 12.

6.

The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development.

Hurd T, Zhou W, Jenkins P, Liu CJ, Swaroop A, Khanna H, Martens J, Hildebrandt F, Margolis B.

Hum Mol Genet. 2010 Nov 15;19(22):4330-44. doi: 10.1093/hmg/ddq355. Epub 2010 Aug 20.

7.

Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling.

Xu C, Rossetti S, Jiang L, Harris PC, Brown-Glaberman U, Wandinger-Ness A, Bacallao R, Alper SL.

Am J Physiol Renal Physiol. 2007 Mar;292(3):F930-45. Epub 2006 Nov 7.

8.

Nek8 regulates the expression and localization of polycystin-1 and polycystin-2.

Sohara E, Luo Y, Zhang J, Manning DK, Beier DR, Zhou J.

J Am Soc Nephrol. 2008 Mar;19(3):469-76. doi: 10.1681/ASN.2006090985. Epub 2008 Jan 30.

9.
10.

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells.

Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, Elia AE, Lu W, Brown EM, Quinn SJ, Ingber DE, Zhou J.

Nat Genet. 2003 Feb;33(2):129-37. Epub 2003 Jan 6.

PMID:
12514735
11.

The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway.

Hartman TR, Liu D, Zilfou JT, Robb V, Morrison T, Watnick T, Henske EP.

Hum Mol Genet. 2009 Jan 1;18(1):151-63. doi: 10.1093/hmg/ddn325. Epub 2008 Oct 9.

12.

Cyst formation following disruption of intracellular calcium signaling.

Kuo IY, DesRochers TM, Kimmerling EP, Nguyen L, Ehrlich BE, Kaplan DL.

Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):14283-8. doi: 10.1073/pnas.1412323111. Epub 2014 Sep 16.

13.

Pkd1 and Nek8 mutations affect cell-cell adhesion and cilia in cysts formed in kidney organ cultures.

Natoli TA, Gareski TC, Dackowski WR, Smith L, Bukanov NO, Russo RJ, Husson H, Matthews D, Piepenhagen P, Ibraghimov-Beskrovnaya O.

Am J Physiol Renal Physiol. 2008 Jan;294(1):F73-83. Epub 2007 Oct 10.

14.

Characterization of single channel currents from primary cilia of renal epithelial cells.

Raychowdhury MK, McLaughlin M, Ramos AJ, Montalbetti N, Bouley R, Ausiello DA, Cantiello HF.

J Biol Chem. 2005 Oct 14;280(41):34718-22. Epub 2005 Aug 3.

15.
16.

STAM and Hrs down-regulate ciliary TRP receptors.

Hu J, Wittekind SG, Barr MM.

Mol Biol Cell. 2007 Sep;18(9):3277-89. Epub 2007 Jun 20.

17.

Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling.

Li Y, Wright JM, Qian F, Germino GG, Guggino WB.

J Biol Chem. 2005 Dec 16;280(50):41298-306. Epub 2005 Oct 13.

18.

OFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblasts.

Jerman S, Ward HH, Lee R, Lopes CA, Fry AM, MacDougall M, Wandinger-Ness A.

PLoS One. 2014 Sep 2;9(9):e106330. doi: 10.1371/journal.pone.0106330. eCollection 2014.

19.

Ciliary calcium signaling is modulated by kidney injury molecule-1 (Kim1).

Kotsis F, Nitschke R, Boehlke C, Bashkurov M, Walz G, Kuehn EW.

Pflugers Arch. 2007 Mar;453(6):819-29. Epub 2007 Jan 5.

PMID:
17205356
20.

L-type calcium channel modulates cystic kidney phenotype.

Jin X, Muntean BS, Aal-Aaboda MS, Duan Q, Zhou J, Nauli SM.

Biochim Biophys Acta. 2014 Sep;1842(9):1518-26. doi: 10.1016/j.bbadis.2014.06.001. Epub 2014 Jun 9.

Items per page

Supplemental Content

Write to the Help Desk