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Results: 1 to 20 of 134

1.

Autophagy and p62 in cardiac proteinopathy.

Zheng Q, Su H, Ranek MJ, Wang X.

Circ Res. 2011 Jul 22;109(3):296-308. doi: 10.1161/CIRCRESAHA.111.244707. Epub 2011 Jun 9.

PMID:
21659648
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes.

Pattison JS, Osinska H, Robbins J.

Circ Res. 2011 Jul 8;109(2):151-60. doi: 10.1161/CIRCRESAHA.110.237339. Epub 2011 May 26.

PMID:
21617129
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Doxycycline attenuates protein aggregation in cardiomyocytes and improves survival of a mouse model of cardiac proteinopathy.

Zheng H, Tang M, Zheng Q, Kumarapeli AR, Horak KM, Tian Z, Wang X.

J Am Coll Cardiol. 2010 Oct 19;56(17):1418-26. doi: 10.1016/j.jacc.2010.01.075.

PMID:
20947000
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Autophagy is an adaptive response in desmin-related cardiomyopathy.

Tannous P, Zhu H, Johnstone JL, Shelton JM, Rajasekaran NS, Benjamin IJ, Nguyen L, Gerard RD, Levine B, Rothermel BA, Hill JA.

Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9745-50. doi: 10.1073/pnas.0706802105. Epub 2008 Jul 9.

PMID:
18621691
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Enhanced autophagy ameliorates cardiac proteinopathy.

Bhuiyan MS, Pattison JS, Osinska H, James J, Gulick J, McLendon PM, Hill JA, Sadoshima J, Robbins J.

J Clin Invest. 2013 Dec 2;123(12):5284-97. doi: 10.1172/JCI70877. Epub 2013 Nov 1.

PMID:
24177425
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

AlphaB-crystallin modulates protein aggregation of abnormal desmin.

Wang X, Klevitsky R, Huang W, Glasford J, Li F, Robbins J.

Circ Res. 2003 Nov 14;93(10):998-1005. Epub 2003 Oct 23.

PMID:
14576194
[PubMed - indexed for MEDLINE]
Free Article
7.

Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy.

Maloyan A, Gulick J, Glabe CG, Kayed R, Robbins J.

Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5995-6000. Epub 2007 Mar 26.

PMID:
17389375
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

p62 expression and autophagy in αB-crystallin R120G mutant knock-in mouse model of hereditary cataract.

Wignes JA, Goldman JW, Weihl CC, Bartley MG, Andley UP.

Exp Eye Res. 2013 Oct;115:263-73. doi: 10.1016/j.exer.2013.06.026. Epub 2013 Jul 18.

PMID:
23872361
[PubMed - indexed for MEDLINE]
9.

Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis.

Sanbe A, Osinska H, Saffitz JE, Glabe CG, Kayed R, Maloyan A, Robbins J.

Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10132-6. Epub 2004 Jun 25.

PMID:
15220483
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Manipulation of death pathways in desmin-related cardiomyopathy.

Maloyan A, Sayegh J, Osinska H, Chua BH, Robbins J.

Circ Res. 2010 May 14;106(9):1524-32. doi: 10.1161/CIRCRESAHA.109.212639. Epub 2010 Apr 1.

PMID:
20360253
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Protein kinase g positively regulates proteasome-mediated degradation of misfolded proteins.

Ranek MJ, Terpstra EJ, Li J, Kass DA, Wang X.

Circulation. 2013 Jul 23;128(4):365-76. doi: 10.1161/CIRCULATIONAHA.113.001971. Epub 2013 Jun 14.

PMID:
23770744
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathy.

Maloyan A, Osinska H, Lammerding J, Lee RT, Cingolani OH, Kass DA, Lorenz JN, Robbins J.

Circ Res. 2009 Apr 24;104(8):1021-8. doi: 10.1161/CIRCRESAHA.108.193516. Epub 2009 Mar 19.

PMID:
19299643
[PubMed - indexed for MEDLINE]
Free Article
13.

Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice.

Wang X, Osinska H, Klevitsky R, Gerdes AM, Nieman M, Lorenz J, Hewett T, Robbins J.

Circ Res. 2001 Jul 6;89(1):84-91.

PMID:
11440982
[PubMed - indexed for MEDLINE]
Free Article
14.

Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy.

Maloyan A, Sanbe A, Osinska H, Westfall M, Robinson D, Imahashi K, Murphy E, Robbins J.

Circulation. 2005 Nov 29;112(22):3451-61.

PMID:
16316967
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

COP9 signalosome regulates autophagosome maturation.

Su H, Li F, Ranek MJ, Wei N, Wang X.

Circulation. 2011 Nov 8;124(19):2117-28. doi: 10.1161/CIRCULATIONAHA.111.048934. Epub 2011 Oct 10.

PMID:
21986281
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice.

Li J, Horak KM, Su H, Sanbe A, Robbins J, Wang X.

J Clin Invest. 2011 Sep;121(9):3689-700. doi: 10.1172/JCI45709. Epub 2011 Aug 15.

PMID:
21841311
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Desmin filaments and cardiac disease: establishing causality.

Wang X, Osinska H, Gerdes AM, Robbins J.

J Card Fail. 2002 Dec;8(6 Suppl):S287-92. Review.

PMID:
12555134
[PubMed - indexed for MEDLINE]
18.

Autophagy and p62 in cardiac protein quality control.

Su H, Wang X.

Autophagy. 2011 Nov;7(11):1382-3. doi: 10.4161/auto.7.11.17339. Epub 2011 Nov 1.

PMID:
21997373
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy.

Sanbe A, Osinska H, Villa C, Gulick J, Klevitsky R, Glabe CG, Kayed R, Robbins J.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13592-7. Epub 2005 Sep 9.

PMID:
16155124
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Intrasarcoplasmic amyloidosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake.

Chen Q, Liu JB, Horak KM, Zheng H, Kumarapeli AR, Li J, Li F, Gerdes AM, Wawrousek EF, Wang X.

Circ Res. 2005 Nov 11;97(10):1018-26. Epub 2005 Oct 6.

PMID:
16210548
[PubMed - indexed for MEDLINE]
Free Article

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