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Items: 1 to 20 of 459

1.

Suppression of TG-interacting factor sensitizes arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells.

Liu ZM, Tseng JT, Hong DY, Huang HS.

Biochem J. 2011 Sep 1;438(2):349-58. doi: 10.1042/BJ20101653.

PMID:
21649584
2.

TG-interacting factor transcriptionally induced by AKT/FOXO3A is a negative regulator that antagonizes arsenic trioxide-induced cancer cell apoptosis.

Liu ZM, Tseng HY, Cheng YL, Yeh BW, Wu WJ, Huang HS.

Toxicol Appl Pharmacol. 2015 May 15;285(1):41-50. doi: 10.1016/j.taap.2015.03.007. Epub 2015 Mar 16.

PMID:
25791921
3.

Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-XL and survivin.

Momeny M, Zakidizaji M, Ghasemi R, Dehpour AR, Rahimi-Balaei M, Abdolazimi Y, Ghavamzadeh A, Alimoghaddam K, Ghaffari SH.

Med Oncol. 2010 Sep;27(3):833-42. doi: 10.1007/s12032-009-9294-9. Epub 2009 Sep 10.

PMID:
19763917
4.

EGF antagonizes TGF-beta-induced tropoelastin expression in lung fibroblasts via stabilization of Smad corepressor TGIF.

Yang S, Nugent MA, Panchenko MP.

Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L143-51. doi: 10.1152/ajplung.00289.2007. Epub 2008 Apr 25.

5.

Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin.

Chiu HW, Ho YS, Wang YJ.

J Mol Med (Berl). 2011 Sep;89(9):927-41. doi: 10.1007/s00109-011-0763-1. Epub 2011 May 19.

PMID:
21594580
6.

Regulation of TG-interacting factor by transforming growth factor-beta.

Chen F, Ogawa K, Nagarajan RP, Zhang M, Kuang C, Chen Y.

Biochem J. 2003 Apr 15;371(Pt 2):257-63.

7.

Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation.

Li Y, Qu X, Qu J, Zhang Y, Liu J, Teng Y, Hu X, Hou K, Liu Y.

Cancer Lett. 2009 Nov 1;284(2):208-15. doi: 10.1016/j.canlet.2009.04.035. Epub 2009 May 19.

PMID:
19457607
8.

The 3'-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly(C)-binding protein.

Giles KM, Daly JM, Beveridge DJ, Thomson AM, Voon DC, Furneaux HM, Jazayeri JA, Leedman PJ.

J Biol Chem. 2003 Jan 31;278(5):2937-46. Epub 2002 Nov 12.

9.

Dissecting the effect of targeting the epidermal growth factor receptor on TGF-β-induced-apoptosis in human hepatocellular carcinoma cells.

Caja L, Sancho P, Bertran E, Fabregat I.

J Hepatol. 2011 Aug;55(2):351-8. doi: 10.1016/j.jhep.2010.10.041. Epub 2010 Dec 13.

PMID:
21147185
10.

Genistein potentiates the effect of arsenic trioxide against human hepatocellular carcinoma: role of Akt and nuclear factor-κB.

Ma Y, Wang J, Liu L, Zhu H, Chen X, Pan S, Sun X, Jiang H.

Cancer Lett. 2011 Feb 1;301(1):75-84. doi: 10.1016/j.canlet.2010.10.022.

PMID:
21078540
11.

Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia.

Lam HK, Li K, Chik KW, Yang M, Liu VC, Li CK, Fok TF, Ng PC, Shing MM, Chuen CK, Yuen PM.

Int J Oncol. 2005 Aug;27(2):537-45.

PMID:
16010437
12.

Inhibition of TGF-β/SMAD3/NF-κB signaling by microRNA-491 is involved in arsenic trioxide-induced anti-angiogenesis in hepatocellular carcinoma cells.

Jiang F, Wang X, Liu Q, Shen J, Li Z, Li Y, Zhang J.

Toxicol Lett. 2014 Nov 18;231(1):55-61. doi: 10.1016/j.toxlet.2014.08.024. Epub 2014 Sep 6.

PMID:
25196641
13.

Arsenic trioxide potentiates the anti-cancer activities of sorafenib against hepatocellular carcinoma by inhibiting Akt activation.

Zhai B, Jiang X, He C, Zhao D, Ma L, Xu L, Jiang H, Sun X.

Tumour Biol. 2015 Apr;36(4):2323-34. doi: 10.1007/s13277-014-2839-3. Epub 2014 Nov 22.

PMID:
25416439
14.

Blockage of JNK pathway enhances arsenic trioxide-induced apoptosis in human keratinocytes.

Huang HS, Liu ZM, Hong DY.

Toxicol Appl Pharmacol. 2010 Apr 15;244(2):234-41. doi: 10.1016/j.taap.2009.12.037. Epub 2010 Jan 11.

PMID:
20074581
15.

Possible roles of a tumor suppressor gene PIG11 in hepatocarcinogenesis and As2O3-induced apoptosis in liver cancer cells.

Liu XM, Xiong XF, Song Y, Tang RJ, Liang XQ, Cao EH.

J Gastroenterol. 2009;44(5):460-9. doi: 10.1007/s00535-009-0030-1. Epub 2009 Apr 1.

PMID:
19333544
16.

Involvement of glycogen synthase kinase-3β in arsenic trioxide-induced p21 expression.

Huang HS, Liu ZM, Cheng YL.

Toxicol Sci. 2011 May;121(1):101-9. doi: 10.1093/toxsci/kfr023. Epub 2011 Jan 27.

17.

Transcriptional and post-transcriptional control of DNA methyltransferase 3B is regulated by phosphatidylinositol 3 kinase/Akt pathway in human hepatocellular carcinoma cell lines.

Mei C, Sun L, Liu Y, Yang Y, Cai X, Liu M, Yao W, Wang C, Li X, Wang L, Li Z, Shi Y, Qiu S, Fan J, Zha X.

J Cell Biochem. 2010 Sep 1;111(1):158-67. doi: 10.1002/jcb.22684.

PMID:
20506537
18.

Synergistic effects of acyclic retinoid and OSI-461 on growth inhibition and gene expression in human hepatoma cells.

Shimizu M, Suzui M, Deguchi A, Lim JT, Xiao D, Hayes JH, Papadopoulos KP, Weinstein IB.

Clin Cancer Res. 2004 Oct 1;10(19):6710-21.

19.

Targeted degradation of the AML1/MDS1/EVI1 oncoprotein by arsenic trioxide.

Shackelford D, Kenific C, Blusztajn A, Waxman S, Ren R.

Cancer Res. 2006 Dec 1;66(23):11360-9.

20.

Down-regulation of CYLD as a trigger for NF-κB activation and a mechanism of apoptotic resistance in hepatocellular carcinoma cells.

Urbanik T, Köhler BC, Boger RJ, Wörns MA, Heeger S, Otto G, Hövelmeyer N, Galle PR, Schuchmann M, Waisman A, Schulze-Bergkamen H.

Int J Oncol. 2011 Jan;38(1):121-31.

PMID:
21109933
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