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Results: 1 to 20 of 92

1.

Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins.

Lima-Fernandes E, Enslen H, Camand E, Kotelevets L, Boularan C, Achour L, Benmerah A, Gibson LC, Baillie GS, Pitcher JA, Chastre E, Etienne-Manneville S, Marullo S, Scott MG.

EMBO J. 2011 Jun 3;30(13):2557-68. doi: 10.1038/emboj.2011.178.

PMID:
21642958
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.

Davidson L, Maccario H, Perera NM, Yang X, Spinelli L, Tibarewal P, Glancy B, Gray A, Weijer CJ, Downes CP, Leslie NR.

Oncogene. 2010 Feb 4;29(5):687-97. doi: 10.1038/onc.2009.384. Epub 2009 Nov 16.

PMID:
19915616
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The protein phosphatase activity of PTEN regulates SRC family kinases and controls glioma migration.

Dey N, Crosswell HE, De P, Parsons R, Peng Q, Su JD, Durden DL.

Cancer Res. 2008 Mar 15;68(6):1862-71. doi: 10.1158/0008-5472.CAN-07-1182.

PMID:
18339867
[PubMed - indexed for MEDLINE]
Free Article
4.

Arresting times for PTEN.

Houslay MD.

EMBO J. 2011 Jul 6;30(13):2513-5. doi: 10.1038/emboj.2011.200. No abstract available.

PMID:
21731046
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells.

Ma J, Sawai H, Ochi N, Matsuo Y, Xu D, Yasuda A, Takahashi H, Wakasugi T, Takeyama H.

Mol Cell Biochem. 2009 Nov;331(1-2):161-71. doi: 10.1007/s11010-009-0154-x. Epub 2009 May 13.

PMID:
19437103
[PubMed - indexed for MEDLINE]
6.

Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity.

Hjelmeland AB, Hjelmeland MD, Shi Q, Hart JL, Bigner DD, Wang XF, Kontos CD, Rich JN.

Cancer Res. 2005 Dec 15;65(24):11276-81.

PMID:
16357132
[PubMed - indexed for MEDLINE]
Free Article
7.

The regulation of cell migration by PTEN.

Leslie NR, Yang X, Downes CP, Weijer CJ.

Biochem Soc Trans. 2005 Dec;33(Pt 6):1507-8. Review.

PMID:
16246156
[PubMed - indexed for MEDLINE]
8.

The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation.

Edwin F, Singh R, Endersby R, Baker SJ, Patel TB.

J Biol Chem. 2006 Feb 24;281(8):4816-22. Epub 2005 Dec 21.

PMID:
16371366
[PubMed - indexed for MEDLINE]
Free Article
9.

Substrate specificity and acute regulation of the tumour suppressor phosphatase, PTEN.

Downes CP, Perera N, Ross S, Leslie NR.

Biochem Soc Symp. 2007;(74):69-80. Review.

PMID:
17233581
[PubMed - indexed for MEDLINE]
10.

Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines.

Wang Y, Romigh T, He X, Orloff MS, Silverman RH, Heston WD, Eng C.

Hum Mol Genet. 2010 Nov 15;19(22):4319-29. doi: 10.1093/hmg/ddq354. Epub 2010 Aug 20.

PMID:
20729295
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The RhoA-ROCK-PTEN pathway as a molecular switch for anchorage dependent cell behavior.

Yang S, Kim HM.

Biomaterials. 2012 Apr;33(10):2902-15. doi: 10.1016/j.biomaterials.2011.12.051. Epub 2012 Jan 13.

PMID:
22244698
[PubMed - indexed for MEDLINE]
12.

MyosinV controls PTEN function and neuronal cell size.

van Diepen MT, Parsons M, Downes CP, Leslie NR, Hindges R, Eickholt BJ.

Nat Cell Biol. 2009 Oct;11(10):1191-6. doi: 10.1038/ncb1961. Epub 2009 Sep 20. Erratum in: Nat Cell Biol. 2009 Nov;11(11):1387.

PMID:
19767745
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling.

Thomas SL, Alam R, Lemke N, Schultz LR, Gutiérrez JA, Rempel SA.

Neuro Oncol. 2010 Sep;12(9):941-55. doi: 10.1093/neuonc/noq048. Epub 2010 May 14.

PMID:
20472716
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Inhibition of apoptosis by MAD1 is mediated by repression of the PTEN tumor suppressor gene.

Rottmann S, Speckgens S, Lüscher-Firzlaff J, Lüscher B.

FASEB J. 2008 Apr;22(4):1124-34. Epub 2007 Nov 12.

PMID:
17998413
[PubMed - indexed for MEDLINE]
Free Article
15.

Upregulation of PTEN by peroxynitrite contributes to cytokine-induced apoptosis in pancreatic beta-cells.

Hou R, Zhang J, Yin T, Cao H, Zhang N, Li X, Wang L, Xing Y, Li D, Ji Q.

Apoptosis. 2010 Aug;15(8):877-86. doi: 10.1007/s10495-010-0510-z.

PMID:
20464496
[PubMed - indexed for MEDLINE]
16.

Simultaneous loss of the DLC1 and PTEN tumor suppressors enhances breast cancer cell migration.

Heering J, Erlmann P, Olayioye MA.

Exp Cell Res. 2009 Sep 10;315(15):2505-14. doi: 10.1016/j.yexcr.2009.05.022. Epub 2009 May 29.

PMID:
19482022
[PubMed - indexed for MEDLINE]
17.

Phosphatase and tensin homolog reconstruction and vascular endothelial growth factor knockdown synergistically inhibit the growth of glioblastoma.

Chen H, Shen X, Guo C, Zhu H, Zhou L, Zhu Y, Wang H, Zheng Y, Huang L.

Cancer Biother Radiopharm. 2010 Dec;25(6):713-21. doi: 10.1089/cbr.2010.0821.

PMID:
21204766
[PubMed - indexed for MEDLINE]
18.

Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation.

Okahara F, Itoh K, Nakagawara A, Murakami M, Kanaho Y, Maehama T.

Mol Biol Cell. 2006 Nov;17(11):4888-95. Epub 2006 Sep 13.

PMID:
16971513
[PubMed - indexed for MEDLINE]
Free PMC Article
19.
20.

The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.

Ahn Y, Hwang CY, Lee SR, Kwon KS, Lee C.

Biochem J. 2008 Jun 1;412(2):331-8. doi: 10.1042/BJ20071403.

PMID:
18307411
[PubMed - indexed for MEDLINE]
Free Article

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