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Results: 1 to 20 of 113

1.

Surface area accessibility and the preferred topology of telomeric DNA quadruplex-ligand complexes.

Haider SM, Autiero I, Neidle S.

Biochimie. 2011 Aug;93(8):1275-9. doi: 10.1016/j.biochi.2011.05.014. Epub 2011 May 30.

PMID:
21641959
[PubMed - indexed for MEDLINE]
2.

Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands.

Collie GW, Promontorio R, Hampel SM, Micco M, Neidle S, Parkinson GN.

J Am Chem Soc. 2012 Feb 8;134(5):2723-31. doi: 10.1021/ja2102423. Epub 2012 Jan 31.

PMID:
22280460
[PubMed - indexed for MEDLINE]
3.

Topology conservation and loop flexibility in quadruplex-drug recognition: crystal structures of inter- and intramolecular telomeric DNA quadruplex-drug complexes.

Parkinson GN, Cuenca F, Neidle S.

J Mol Biol. 2008 Sep 19;381(5):1145-56. doi: 10.1016/j.jmb.2008.06.022. Epub 2008 Jun 17.

PMID:
18619463
[PubMed - indexed for MEDLINE]
4.

Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders.

Alcaro S, Artese A, Costa G, Distinto S, Ortuso F, Parrotta L.

Biochimie. 2011 Aug;93(8):1267-74. doi: 10.1016/j.biochi.2011.06.014. Epub 2011 Jun 16.

PMID:
21699954
[PubMed - indexed for MEDLINE]
5.

Template-assembled synthetic G-quadruplex (TASQ): a useful system for investigating the interactions of ligands with constrained quadruplex topologies.

Murat P, Bonnet R, Van der Heyden A, Spinelli N, Labbé P, Monchaud D, Teulade-Fichou MP, Dumy P, Defrancq E.

Chemistry. 2010 May 25;16(20):6106-14. doi: 10.1002/chem.200903456.

PMID:
20397247
[PubMed - indexed for MEDLINE]
6.

Energetics of the human Tel-22 quadruplex-telomestatin interaction: a molecular dynamics study.

Agrawal S, Ojha RP, Maiti S.

J Phys Chem B. 2008 Jun 5;112(22):6828-36. doi: 10.1021/jp7102676. Epub 2008 May 8.

PMID:
18461983
[PubMed - indexed for MEDLINE]
7.

Selection of G-quadruplex folding topology with LNA-modified human telomeric sequences in K+ solution.

Pradhan D, Hansen LH, Vester B, Petersen M.

Chemistry. 2011 Feb 18;17(8):2405-13. doi: 10.1002/chem.201001961. Epub 2011 Jan 24.

PMID:
21264960
[PubMed - indexed for MEDLINE]
8.

New insights into the structures of ligand-quadruplex complexes from molecular dynamics simulations.

Hou JQ, Chen SB, Tan JH, Ou TM, Luo HB, Li D, Xu J, Gu LQ, Huang ZS.

J Phys Chem B. 2010 Nov 25;114(46):15301-10. doi: 10.1021/jp106683n. Epub 2010 Nov 4.

PMID:
21049896
[PubMed - indexed for MEDLINE]
9.

Selectivity of small molecule ligands for parallel and anti-parallel DNA G-quadruplex structures.

Garner TP, Williams HE, Gluszyk KI, Roe S, Oldham NJ, Stevens MF, Moses JE, Searle MS.

Org Biomol Chem. 2009 Oct 21;7(20):4194-200. doi: 10.1039/b910505k. Epub 2009 Aug 14.

PMID:
19795057
[PubMed - indexed for MEDLINE]
10.

A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple.

Kuryavyi V, Majumdar A, Shallop A, Chernichenko N, Skripkin E, Jones R, Patel DJ.

J Mol Biol. 2001 Jun 29;310(1):181-94.

PMID:
11419945
[PubMed - indexed for MEDLINE]
11.

Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure.

Rezler EM, Seenisamy J, Bashyam S, Kim MY, White E, Wilson WD, Hurley LH.

J Am Chem Soc. 2005 Jul 6;127(26):9439-47.

PMID:
15984871
[PubMed - indexed for MEDLINE]
12.

Structure of a G-quadruplex-ligand complex.

Haider SM, Parkinson GN, Neidle S.

J Mol Biol. 2003 Feb 7;326(1):117-25.

PMID:
12547195
[PubMed - indexed for MEDLINE]
13.

Structural basis of telomeric RNA quadruplex--acridine ligand recognition.

Collie GW, Sparapani S, Parkinson GN, Neidle S.

J Am Chem Soc. 2011 Mar 2;133(8):2721-8. doi: 10.1021/ja109767y. Epub 2011 Feb 3.

PMID:
21291211
[PubMed - indexed for MEDLINE]
14.

Cross-links of quadruplex structures from human telomeric DNA by dinuclear platinum complexes show the flexibility of both structures.

Ourliac-Garnier I, Elizondo-Riojas MA, Redon S, Farrell NP, Bombard S.

Biochemistry. 2005 Aug 9;44(31):10620-34.

PMID:
16060671
[PubMed - indexed for MEDLINE]
15.

Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.

Wu WB, Chen SH, Hou JQ, Tan JH, Ou TM, Huang SL, Li D, Gu LQ, Huang ZS.

Org Biomol Chem. 2011 Apr 21;9(8):2975-86. doi: 10.1039/c0ob00921k. Epub 2011 Mar 3.

PMID:
21373680
[PubMed - indexed for MEDLINE]
16.

Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures.

Zhang Z, Dai J, Veliath E, Jones RA, Yang D.

Nucleic Acids Res. 2010 Jan;38(3):1009-21. doi: 10.1093/nar/gkp1029. Epub 2009 Nov 27.

PMID:
19946019
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Structural stability analysis of the intermediates in the folding pathway of human telomeric hybrid-1 G-quadruplex based on fragment molecular orbital method.

Yagi H, Mashimo T, Sannohe Y, Sugiyama H.

Nucleic Acids Symp Ser (Oxf). 2008;(52):161-2. doi: 10.1093/nass/nrn082.

PMID:
18776303
[PubMed - indexed for MEDLINE]
Free Article
18.

Preferential binding of a G-quadruplex ligand to human chromosome ends.

Granotier C, Pennarun G, Riou L, Hoffschir F, Gauthier LR, De Cian A, Gomez D, Mandine E, Riou JF, Mergny JL, Mailliet P, Dutrillaux B, Boussin FD.

Nucleic Acids Res. 2005 Jul 28;33(13):4182-90. Print 2005.

PMID:
16052031
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Recognize three different human telomeric G-quadruplex conformations by quinacrine.

Sun H, Xiang J, Li Q, Liu Y, Li L, Shang Q, Xu G, Tang Y.

Analyst. 2012 Feb 21;137(4):862-7. doi: 10.1039/c2an15870a. Epub 2012 Jan 5.

PMID:
22223064
[PubMed - indexed for MEDLINE]
20.

Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation.

Dai J, Punchihewa C, Ambrus A, Chen D, Jones RA, Yang D.

Nucleic Acids Res. 2007;35(7):2440-50. Epub 2007 Mar 29.

PMID:
17395643
[PubMed - indexed for MEDLINE]
Free PMC Article
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