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Items: 1 to 20 of 119

1.

Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities.

Mohamed ME, Frye RF.

Drug Metab Dispos. 2011 Sep;39(9):1522-8. doi: 10.1124/dmd.111.039602. Epub 2011 Jun 1.

2.

Inhibitory effects of commonly used herbal extracts on UGT1A1 enzyme activity.

Mohamed MF, Tseng T, Frye RF.

Xenobiotica. 2010 Oct;40(10):663-9. doi: 10.3109/00498254.2010.505669.

PMID:
20666626
3.

Effect of efavirenz on UDP-glucuronosyltransferase 1A1, 1A4, 1A6, and 1A9 activities in human liver microsomes.

Ji HY, Lee H, Lim SR, Kim JH, Lee HS.

Molecules. 2012 Jan 17;17(1):851-60. doi: 10.3390/molecules17010851.

4.

Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors.

Walsky RL, Bauman JN, Bourcier K, Giddens G, Lapham K, Negahban A, Ryder TF, Obach RS, Hyland R, Goosen TC.

Drug Metab Dispos. 2012 May;40(5):1051-65. doi: 10.1124/dmd.111.043117. Epub 2012 Feb 22.

5.

Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.

Yamanaka H, Nakajima M, Katoh M, Kanoh A, Tamura O, Ishibashi H, Yokoi T.

Drug Metab Dispos. 2005 Jan;33(1):23-30. Epub 2004 Oct 6.

6.

Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin.

Hanioka N, Ozawa S, Jinno H, Ando M, Saito Y, Sawada J.

Xenobiotica. 2001 Oct;31(10):687-99.

PMID:
11695848
7.
8.

Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.

Fujiwara R, Nakajima M, Yamanaka H, Katoh M, Yokoi T.

Drug Metab Dispos. 2008 Feb;36(2):361-7. Epub 2007 Nov 12.

9.

Characterization of niflumic acid as a selective inhibitor of human liver microsomal UDP-glucuronosyltransferase 1A9: application to the reaction phenotyping of acetaminophen glucuronidation.

Miners JO, Bowalgaha K, Elliot DJ, Baranczewski P, Knights KM.

Drug Metab Dispos. 2011 Apr;39(4):644-52. doi: 10.1124/dmd.110.037036. Epub 2011 Jan 18.

10.

In vitro selective inhibition of human UDP-glucuronosyltransferase (UGT) 1A4 by finasteride, and prediction of in vivo drug-drug interactions.

Lee SJ, Park JB, Kim D, Bae SH, Chin YW, Oh E, Bae SK.

Toxicol Lett. 2015 Jan 22;232(2):458-65. doi: 10.1016/j.toxlet.2014.11.018. Epub 2014 Nov 20.

PMID:
25448279
11.

Imipramine N-glucuronidation in human liver microsomes: biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms.

Nakajima M, Tanaka E, Kobayashi T, Ohashi N, Kume T, Yokoi T.

Drug Metab Dispos. 2002 Jun;30(6):636-42.

12.

Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activities.

Fujiwara R, Nakajima M, Yamanaka H, Katoh M, Yokoi T.

Drug Metab Dispos. 2007 Oct;35(10):1781-7. Epub 2007 Jul 9.

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14.

Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4.

Aprile S, Del Grosso E, Grosa G.

Drug Metab Dispos. 2010 Jul;38(7):1141-6. doi: 10.1124/dmd.109.031435. Epub 2010 Apr 7.

15.

Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4.

Kaku T, Ogura K, Nishiyama T, Ohnuma T, Muro K, Hiratsuka A.

Biochem Pharmacol. 2004 Jun 1;67(11):2093-102.

PMID:
15135306
16.

Glucuronidation of etoposide in human liver microsomes is specifically catalyzed by UDP-glucuronosyltransferase 1A1.

Watanabe Y, Nakajima M, Ohashi N, Kume T, Yokoi T.

Drug Metab Dispos. 2003 May;31(5):589-95.

17.

Evaluation of 5-hydroxytryptophol and other endogenous serotonin (5-hydroxytryptamine) analogs as substrates for UDP-glucuronosyltransferase 1A6.

Krishnaswamy S, Hao Q, Von Moltke LL, Greenblatt DJ, Court MH.

Drug Metab Dispos. 2004 Aug;32(8):862-9.

18.

Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.

Ma L, Sun J, Peng Y, Zhang R, Shao F, Hu X, Zhu J, Wang X, Cheng X, Zhu Y, Wan P, Feng D, Wu H, Wang G.

Drug Metab Dispos. 2012 Apr;40(4):734-41. doi: 10.1124/dmd.111.043356. Epub 2012 Jan 11.

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