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Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major trauma.

Rushefski M, Aplenc R, Meyer N, Li M, Feng R, Lanken PN, Gallop R, Bellamy S, Localio AR, Feinstein SI, Fisher AB, Albelda SM, Christie JD.

BMC Med Genet. 2011 May 31;12:77. doi: 10.1186/1471-2350-12-77.


SNP-set analysis replicates acute lung injury genetic risk factors.

Meyer NJ, Daye ZJ, Rushefski M, Aplenc R, Lanken PN, Shashaty MG, Christie JD, Feng R.

BMC Med Genet. 2012 Jun 28;13:52. doi: 10.1186/1471-2350-13-52.


Novel polymorphisms in the myosin light chain kinase gene confer risk for acute lung injury.

Gao L, Grant A, Halder I, Brower R, Sevransky J, Maloney JP, Moss M, Shanholtz C, Yates CR, Meduri GU, Shriver MD, Ingersoll R, Scott AF, Beaty TH, Moitra J, Ma SF, Ye SQ, Barnes KC, Garcia JG.

Am J Respir Cell Mol Biol. 2006 Apr;34(4):487-95. Epub 2006 Jan 6.


ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio.

Meyer NJ, Li M, Feng R, Bradfield J, Gallop R, Bellamy S, Fuchs BD, Lanken PN, Albelda SM, Rushefski M, Aplenc R, Abramova H, Atochina-Vasserman EN, Beers MF, Calfee CS, Cohen MJ, Pittet JF, Christiani DC, O'Keefe GE, Ware LB, May AK, Wurfel MM, Hakonarson H, Christie JD.

Am J Respir Crit Care Med. 2011 May 15;183(10):1344-53. doi: 10.1164/rccm.201005-0701OC. Epub 2011 Jan 21.


Variation in the myosin light chain kinase gene is associated with development of acute lung injury after major trauma.

Christie JD, Ma SF, Aplenc R, Li M, Lanken PN, Shah CV, Fuchs B, Albelda SM, Flores C, Garcia JG.

Crit Care Med. 2008 Oct;36(10):2794-800.


Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma.

Christie JD, Wurfel MM, Feng R, O'Keefe GE, Bradfield J, Ware LB, Christiani DC, Calfee CS, Cohen MJ, Matthay M, Meyer NJ, Kim C, Li M, Akey J, Barnes KC, Sevransky J, Lanken PN, May AK, Aplenc R, Maloney JP, Hakonarson H; Trauma ALI SNP Consortium (TASC) investigators.

PLoS One. 2012;7(1):e28268. doi: 10.1371/journal.pone.0028268. Epub 2012 Jan 25.


Norrie disease gene sequence variants in an ethnically diverse population with retinopathy of prematurity.

Hutcheson KA, Paluru PC, Bernstein SL, Koh J, Rappaport EF, Leach RA, Young TL.

Mol Vis. 2005 Jul 14;11:501-8.


Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort.

Cheng I, Penney KL, Stram DO, Le Marchand L, Giorgi E, Haiman CA, Kolonel LN, Pike M, Hirschhorn J, Henderson BE, Freedman ML.

Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1993-7.


A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort.

Lee SA, Haiman CA, Burtt NP, Pooler LC, Cheng I, Kolonel LN, Pike MC, Altshuler D, Hirschhorn JN, Henderson BE, Stram DO.

BMC Med Genet. 2007 Dec 1;8:72.


The influence of genetic variation in surfactant protein B on severe lung injury in African American children.

Dahmer MK, O'cain P, Patwari PP, Simpson P, Li SH, Halligan N, Quasney MW.

Crit Care Med. 2011 May;39(5):1138-44. doi: 10.1097/CCM.0b013e31820a9416.


Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction.

Yuferov V, Fussell D, LaForge KS, Nielsen DA, Gordon D, Ho A, Leal SM, Ott J, Kreek MJ.

Pharmacogenetics. 2004 Dec;14(12):793-804.


Evaluation of genetic variation and association in the matrix metalloproteinase 9 (MMP9) gene in ESRD patients.

Hirakawa S, Lange EM, Colicigno CJ, Freedman BI, Rich SS, Bowden DW.

Am J Kidney Dis. 2003 Jul;42(1):133-42.


Sequence variation and linkage disequilibrium in the GABA transporter-1 gene (SLC6A1) in five populations: implications for pharmacogenetic research.

Hirunsatit R, Ilomäki R, Malison R, Räsänen P, Ilomäki E, Kranzler HR, Kosten T, Sughondhabirom A, Thavichachart N, Tangwongchai S, Listman J, Mutirangura A, Gelernter J, Lappalainen J.

BMC Genet. 2007 Oct 17;8:71.


Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality.

Arcaroli JJ, Hokanson JE, Abraham E, Geraci M, Murphy JR, Bowler RP, Dinarello CA, Silveira L, Sankoff J, Heyland D, Wischmeyer P, Crapo JD.

Am J Respir Crit Care Med. 2009 Jan 15;179(2):105-12. doi: 10.1164/rccm.200710-1566OC. Epub 2008 Oct 23.


Functional genetic variants in the 3'-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity.

Yu X, Dhakal IB, Beggs M, Edavana VK, Williams S, Zhang X, Mercer K, Ning B, Lang NP, Kadlubar FF, Kadlubar S.

Toxicol Sci. 2010 Dec;118(2):391-403. doi: 10.1093/toxsci/kfq296. Epub 2010 Sep 29.


Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant.

Palmer ND, Hester JM, An SS, Adeyemo A, Rotimi C, Langefeld CD, Freedman BI, Ng MC, Bowden DW.

Diabetes. 2011 Feb;60(2):662-8. doi: 10.2337/db10-0134. Epub 2010 Oct 27.


Further evidence for association of the RGS2 gene with antipsychotic-induced parkinsonism: protective role of a functional polymorphism in the 3'-untranslated region.

Greenbaum L, Smith RC, Rigbi A, Strous R, Teltsh O, Kanyas K, Korner M, Lancet D, Ben-Asher E, Lerer B.

Pharmacogenomics J. 2009 Apr;9(2):103-10. doi: 10.1038/tpj.2008.6. Epub 2008 Mar 18.


Genetic variation in the FAS gene and associations with acute lung injury.

Glavan BJ, Holden TD, Goss CH, Black RA, Neff MJ, Nathens AB, Martin TR, Wurfel MM; ARDSnet Investigators.

Am J Respir Crit Care Med. 2011 Feb 1;183(3):356-63. doi: 10.1164/rccm.201003-0351OC. Epub 2010 Sep 2.


Patterns of association between PPARgamma genetic variation and indices of adiposity and insulin action in African-Americans and whites: the CARDIA Study.

Wei Q, Jacobs DR Jr, Schreiner PJ, Siscovick DS, Steffes MW, Fornage M.

J Mol Med (Berl). 2006 Nov;84(11):955-65. Epub 2006 Sep 6.


Association of interleukin-1 gene variations with moderate to severe chronic periodontitis in multiple ethnicities.

Wu X, Offenbacher S, Lόpez NJ, Chen D, Wang HY, Rogus J, Zhou J, Beck J, Jiang S, Bao X, Wilkins L, Doucette-Stamm L, Kornman K.

J Periodontal Res. 2015 Feb;50(1):52-61. doi: 10.1111/jre.12181. Epub 2014 Apr 2.

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