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Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques.

Vanderford TH, Bleckwehl C, Engram JC, Dunham RM, Klatt NR, Feinberg MB, Garber DA, Betts MR, Silvestri G.

PLoS Pathog. 2011 May;7(5):e1002048. doi: 10.1371/journal.ppat.1002048. Epub 2011 May 19.


Multiplexed Component Analysis to Identify Genes Contributing to the Immune Response during Acute SIV Infection.

Hosseini I, Gama L, Mac Gabhann F.

PLoS One. 2015 May 18;10(5):e0126843. doi: 10.1371/journal.pone.0126843. eCollection 2015.


Reply to "Comments on Fouchier's calculation of risk and elapsed time for escape of a laboratory-acquired infection from his laboratory".

Fouchier RA.

MBio. 2015 Apr 14;6(2). pii: e00407-15. doi: 10.1128/mBio.00407-15. No abstract available.


Comments on Fouchier's calculation of risk and elapsed time for escape of a laboratory-acquired infection from his laboratory.

Klotz LC.

MBio. 2015 Apr 14;6(2). pii: e00268-15. doi: 10.1128/mBio.00268-15. No abstract available.


Epitope-specific CD8+ T cell kinetics rather than viral variability determine the timing of immune escape in simian immunodeficiency virus infection.

Martyushev AP, Petravic J, Grimm AJ, Alinejad-Rokny H, Gooneratne SL, Reece JC, Cromer D, Kent SJ, Davenport MP.

J Immunol. 2015 May 1;194(9):4112-21. doi: 10.4049/jimmunol.1400793. Epub 2015 Mar 30.


AIDS virus seeks refuge in B cell follicles.

Streeck H.

Nat Med. 2015 Feb;21(2):111-2. doi: 10.1038/nm.3795. No abstract available.


Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL.

Connick E, Folkvord JM, Lind KT, Rakasz EG, Miles B, Wilson NA, Santiago ML, Schmitt K, Stephens EB, Kim HO, Wagstaff R, Li S, Abdelaal HM, Kemp N, Watkins DI, MaWhinney S, Skinner PJ.

J Immunol. 2014 Dec 1;193(11):5613-25. doi: 10.4049/jimmunol.1401161. Epub 2014 Oct 31.


Linking pig-tailed macaque major histocompatibility complex class I haplotypes and cytotoxic T lymphocyte escape mutations in simian immunodeficiency virus infection.

Gooneratne SL, Alinejad-Rokny H, Ebrahimi D, Bohn PS, Wiseman RW, O'Connor DH, Davenport MP, Kent SJ.

J Virol. 2014 Dec;88(24):14310-25. doi: 10.1128/JVI.02428-14. Epub 2014 Oct 1.


Chronic binge alcohol increases susceptibility to rectal simian immunodeficiency virus infection in macaques.

Amedee AM, Veazey R, Molina P, Nelson S, Bagby GJ.

AIDS. 2014 Oct 23;28(16):2485-7. doi: 10.1097/QAD.0000000000000413. No abstract available.


Diminished viral control during simian immunodeficiency virus infection is associated with aberrant PD-1hi CD4 T cell enrichment in the lymphoid follicles of the rectal mucosa.

Mylvaganam GH, Velu V, Hong JJ, Sadagopal S, Kwa S, Basu R, Lawson B, Villinger F, Amara RR.

J Immunol. 2014 Nov 1;193(9):4527-36. doi: 10.4049/jimmunol.1401222. Epub 2014 Sep 22.


Virus-host mucosal interactions during early SIV rectal transmission.

Lu W, Ma F, Churbanov A, Wan Y, Li Y, Kang G, Yuan Z, Wang D, Zhang C, Xu J, Lewis M, Li Q.

Virology. 2014 Sep;464-465:406-14. doi: 10.1016/j.virol.2014.07.010. Epub 2014 Aug 14.


Resistance to simian immunodeficiency virus low dose rectal challenge is associated with higher constitutive TRIM5α expression in PBMC.

Aamer HA, Rajakumar P, Nyaundi J, Murphey-Corb M.

Retrovirology. 2014 May 23;11:39. doi: 10.1186/1742-4690-11-39.


Phenotypes and distribution of mucosal memory B-cell populations in the SIV/SHIV rhesus macaque model.

Demberg T, Mohanram V, Venzon D, Robert-Guroff M.

Clin Immunol. 2014 Aug;153(2):264-76. doi: 10.1016/j.clim.2014.04.017. Epub 2014 May 9.


Deep transcriptional sequencing of mucosal challenge compartment from rhesus macaques acutely infected with simian immunodeficiency virus implicates loss of cell adhesion preceding immune activation.

Barrenas F, Palermo RE, Agricola B, Agy MB, Aicher L, Carter V, Flanary L, Green RR, McLain R, Li Q, Lu W, Murnane R, Peng X, Thomas MJ, Weiss JM, Anderson DM, Katze MG.

J Virol. 2014 Jul;88(14):7962-72. doi: 10.1128/JVI.00543-14. Epub 2014 May 7.


Accumulation of functionally immature myeloid dendritic cells in lymph nodes of rhesus macaques with acute pathogenic simian immunodeficiency virus infection.

Wijewardana V, Bouwer AL, Brown KN, Liu X, Barratt-Boyes SM.

Immunology. 2014 Oct;143(2):146-54. doi: 10.1111/imm.12295.


Mathematical modeling of escape of HIV from cytotoxic T lymphocyte responses.

Ganusov VV, Neher RA, Perelson AS.

J Stat Mech. 2013 Jan 1;2013:P01010.


Constructing lower-bounds for CTL escape rates in early SIV infection.

Leviyang S.

J Theor Biol. 2014 Jul 7;352:82-91. doi: 10.1016/j.jtbi.2014.02.020. Epub 2014 Mar 3.


SIV vpx is essential for macrophage infection but not for development of AIDS.

Westmoreland SV, Converse AP, Hrecka K, Hurley M, Knight H, Piatak M, Lifson J, Mansfield KG, Skowronski J, Desrosiers RC.

PLoS One. 2014 Jan 21;9(1):e84463. doi: 10.1371/journal.pone.0084463. eCollection 2014.


Tertiary mutations stabilize CD8+ T lymphocyte escape-associated compensatory mutations following transmission of simian immunodeficiency virus.

Burwitz BJ, Wu HL, Reed JS, Hammond KB, Newman LP, Bimber BN, Nimiyongskul FA, Leon EJ, Maness NJ, Friedrich TC, Yokoyama M, Sato H, Matano T, O'Connor DH, Sacha JB.

J Virol. 2014 Mar;88(6):3598-604. doi: 10.1128/JVI.03304-13. Epub 2013 Dec 26.


Estimating the contribution of the gut to plasma viral load in early SIV infection.

Petravic J, Vanderford TH, Silvestri G, Davenport M.

Retrovirology. 2013 Oct 14;10:105. doi: 10.1186/1742-4690-10-105.

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