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Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach.

Scott MC, Sarver AL, Gavin KJ, Thayanithy V, Getzy DM, Newman RA, Cutter GR, Lindblad-Toh K, Kisseberth WC, Hunter LE, Subramanian S, Breen M, Modiano JF.

Bone. 2011 Sep;49(3):356-67. doi: 10.1016/j.bone.2011.05.008. Epub 2011 May 15.


Gene expression profiling of canine osteosarcoma reveals genes associated with short and long survival times.

Selvarajah GT, Kirpensteijn J, van Wolferen ME, Rao NA, Fieten H, Mol JA.

Mol Cancer. 2009 Sep 7;8:72. doi: 10.1186/1476-4598-8-72.


mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts.

Kuijjer ML, Namløs HM, Hauben EI, Machado I, Kresse SH, Serra M, Llombart-Bosch A, Hogendoorn PC, Meza-Zepeda LA, Myklebost O, Cleton-Jansen AM.

BMC Med Genomics. 2011 Sep 20;4:66. doi: 10.1186/1755-8794-4-66.


Molecular classification of osteosarcoma.

Lau CC.

Cancer Treat Res. 2009;152:459-65. doi: 10.1007/978-1-4419-0284-9_26. Review.


MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma.

Sarver AL, Thayanithy V, Scott MC, Cleton-Jansen AM, Hogendoorn PC, Modiano JF, Subramanian S.

Orphanet J Rare Dis. 2013 Jan 11;8:7. doi: 10.1186/1750-1172-8-7.


Microarray analysis identifies distinct gene expression profiles associated with histological subtype in human osteosarcoma.

Kubista B, Klinglmueller F, Bilban M, Pfeiffer M, Lass R, Giurea A, Funovics PT, Toma C, Dominkus M, Kotz R, Thalhammer T, Trieb K, Zettl T, Singer CF.

Int Orthop. 2011 Mar;35(3):401-11. doi: 10.1007/s00264-010-0996-6. Epub 2010 Mar 26.


Tumor-infiltrating macrophages are associated with metastasis suppression in high-grade osteosarcoma: a rationale for treatment with macrophage activating agents.

Buddingh EP, Kuijjer ML, Duim RA, Bürger H, Agelopoulos K, Myklebost O, Serra M, Mertens F, Hogendoorn PC, Lankester AC, Cleton-Jansen AM.

Clin Cancer Res. 2011 Apr 15;17(8):2110-9. doi: 10.1158/1078-0432.CCR-10-2047. Epub 2011 Mar 3.


Characterization of canine osteosarcoma by array comparative genomic hybridization and RT-qPCR: signatures of genomic imbalance in canine osteosarcoma parallel the human counterpart.

Angstadt AY, Motsinger-Reif A, Thomas R, Kisseberth WC, Guillermo Couto C, Duval DL, Nielsen DM, Modiano JF, Breen M.

Genes Chromosomes Cancer. 2011 Nov;50(11):859-74. doi: 10.1002/gcc.20908. Epub 2011 Aug 11.


Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression.

Paoloni M, Davis S, Lana S, Withrow S, Sangiorgi L, Picci P, Hewitt S, Triche T, Meltzer P, Khanna C.

BMC Genomics. 2009 Dec 23;10:625. doi: 10.1186/1471-2164-10-625.


Genomic signatures of chromosomal instability and osteosarcoma progression detected by high resolution array CGH and interphase FISH.

Selvarajah S, Yoshimoto M, Ludkovski O, Park PC, Bayani J, Thorner P, Maire G, Squire JA, Zielenska M.

Cytogenet Genome Res. 2008;122(1):5-15. doi: 10.1159/000151310. Epub 2008 Oct 14.


Genomic alterations and allelic imbalances are strong prognostic predictors in osteosarcoma.

Smida J, Baumhoer D, Rosemann M, Walch A, Bielack S, Poremba C, Remberger K, Korsching E, Scheurlen W, Dierkes C, Burdach S, Jundt G, Atkinson MJ, Nathrath M.

Clin Cancer Res. 2010 Aug 15;16(16):4256-67. doi: 10.1158/1078-0432.CCR-10-0284. Epub 2010 Jul 7.


Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data.

Kuijjer ML, Rydbeck H, Kresse SH, Buddingh EP, Lid AB, Roelofs H, Bürger H, Myklebost O, Hogendoorn PC, Meza-Zepeda LA, Cleton-Jansen AM.

Genes Chromosomes Cancer. 2012 Jul;51(7):696-706. doi: 10.1002/gcc.21956. Epub 2012 Mar 27.


Genome-wide transcriptome profile of the human osteosarcoma Sa OS and U-2 OS cell lines.

Trougakos IP, Chondrogianni N, Amarantos I, Blake J, Schwager C, Wirkner U, Ansorge W, Gonos ES.

Cancer Genet Cytogenet. 2010 Jan 15;196(2):109-18. doi: 10.1016/j.cancergencyto.2009.09.012.


Gene expression profiles of human osteosarcoma cell sublines with different pulmonary metastatic potentials.

Chen X, Yang TT, Qiu XC, Ji ZG, Li CX, Long H, Zhou Y, Ma BA, Ma Q, Zhang X, Fan QY.

Cancer Biol Ther. 2011 Jan 15;11(2):287-92. Epub 2011 Jan 15.


Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms.

Sørlie T, Wang Y, Xiao C, Johnsen H, Naume B, Samaha RR, Børresen-Dale AL.

BMC Genomics. 2006 May 26;7:127.


Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value.

Marisa L, de Reyniès A, Duval A, Selves J, Gaub MP, Vescovo L, Etienne-Grimaldi MC, Schiappa R, Guenot D, Ayadi M, Kirzin S, Chazal M, Fléjou JF, Benchimol D, Berger A, Lagarde A, Pencreach E, Piard F, Elias D, Parc Y, Olschwang S, Milano G, Laurent-Puig P, Boige V.

PLoS Med. 2013;10(5):e1001453. doi: 10.1371/journal.pmed.1001453. Epub 2013 May 21.


Genetic and molecular characterization of the human osteosarcoma 3AB-OS cancer stem cell line: a possible model for studying osteosarcoma origin and stemness.

Di Fiore R, Fanale D, Drago-Ferrante R, Chiaradonna F, Giuliano M, De Blasio A, Amodeo V, Corsini LR, Bazan V, Tesoriere G, Vento R, Russo A.

J Cell Physiol. 2013 Jun;228(6):1189-201. doi: 10.1002/jcp.24272.


SAS is amplified predominantly in surface osteosarcoma.

Noble-Topham SE, Burrow SR, Eppert K, Kandel RA, Meltzer PS, Bell RS, Andrulis IL.

J Orthop Res. 1996 Sep;14(5):700-5.


[Molecular characterization of osteosarcomas].

Baumhoer D.

Pathologe. 2013 Nov;34 Suppl 2:260-3. doi: 10.1007/s00292-013-1823-9. Review. German.


Analysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma.

Maire G, Martin JW, Yoshimoto M, Chilton-MacNeill S, Zielenska M, Squire JA.

Cancer Genet. 2011 Mar;204(3):138-46. doi: 10.1016/j.cancergen.2010.12.012.

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