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Items: 1 to 20 of 190


Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice.

Scott MM, Williams KW, Rossi J, Lee CE, Elmquist JK.

J Clin Invest. 2011 Jun;121(6):2413-21. doi: 10.1172/JCI43703. Epub 2011 May 23.


Control of blood pressure, appetite, and glucose by leptin in mice lacking leptin receptors in proopiomelanocortin neurons.

do Carmo JM, da Silva AA, Cai Z, Lin S, Dubinion JH, Hall JE.

Hypertension. 2011 May;57(5):918-26. doi: 10.1161/HYPERTENSIONAHA.110.161349. Epub 2011 Mar 21.


The roles of leptin receptors on POMC neurons in the regulation of sex-specific energy homeostasis.

Shi H, Sorrell JE, Clegg DJ, Woods SC, Seeley RJ.

Physiol Behav. 2010 May 11;100(2):165-72. doi: 10.1016/j.physbeh.2010.02.018. Epub 2010 Mar 1.


Genetic dissection of neuronal pathways controlling energy homeostasis.

Balthasar N.

Obesity (Silver Spring). 2006 Aug;14 Suppl 5:222S-227S. Review.


Shp2 signaling in POMC neurons is important for leptin's actions on blood pressure, energy balance, and glucose regulation.

do Carmo JM, da Silva AA, Ebaady SE, Sessums PO, Abraham RS, Elmquist JK, Lowell BB, Hall JE.

Am J Physiol Regul Integr Comp Physiol. 2014 Dec 15;307(12):R1438-47. doi: 10.1152/ajpregu.00131.2014. Epub 2014 Oct 22.


Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice.

Berglund ED, Vianna CR, Donato J Jr, Kim MH, Chuang JC, Lee CE, Lauzon DA, Lin P, Brule LJ, Scott MM, Coppari R, Elmquist JK.

J Clin Invest. 2012 Mar;122(3):1000-9. doi: 10.1172/JCI59816. Epub 2012 Feb 13.


Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome.

Bingham NC, Anderson KK, Reuter AL, Stallings NR, Parker KL.

Endocrinology. 2008 May;149(5):2138-48. doi: 10.1210/en.2007-1200. Epub 2008 Feb 7.


IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action.

Sadagurski M, Leshan RL, Patterson C, Rozzo A, Kuznetsova A, Skorupski J, Jones JC, Depinho RA, Myers MG Jr, White MF.

Cell Metab. 2012 May 2;15(5):703-12. doi: 10.1016/j.cmet.2012.04.011.


TXNIP in Agrp neurons regulates adiposity, energy expenditure, and central leptin sensitivity.

Blouet C, Liu SM, Jo YH, Chua S, Schwartz GJ.

J Neurosci. 2012 Jul 18;32(29):9870-7. doi: 10.1523/JNEUROSCI.0353-12.2012.


TrkB receptor signaling in the nucleus tractus solitarius mediates the food intake-suppressive effects of hindbrain BDNF and leptin.

Spaeth AM, Kanoski SE, Hayes MR, Grill HJ.

Am J Physiol Endocrinol Metab. 2012 May 1;302(10):E1252-60. doi: 10.1152/ajpendo.00025.2012. Epub 2012 Feb 28.


Neuroanatomy of body weight control: lessons learned from leptin.

Williams DL, Schwartz MW.

J Clin Invest. 2011 Jun;121(6):2152-5. doi: 10.1172/JCI58027. Epub 2011 May 23.


Leptin receptor signaling in midbrain dopamine neurons regulates feeding.

Hommel JD, Trinko R, Sears RM, Georgescu D, Liu ZW, Gao XB, Thurmon JJ, Marinelli M, DiLeone RJ.

Neuron. 2006 Sep 21;51(6):801-10.


Obesity and downregulated hypothalamic leptin receptors in male metallothionein-3-null mice.

Byun HR, Kim DK, Koh JY.

Neurobiol Dis. 2011 Oct;44(1):125-32. doi: 10.1016/j.nbd.2011.06.012. Epub 2011 Jun 25.


Role of proopiomelanocortin neuron Stat3 in regulating arterial pressure and mediating the chronic effects of leptin.

Dubinion JH, do Carmo JM, Adi A, Hamza S, da Silva AA, Hall JE.

Hypertension. 2013 May;61(5):1066-74. doi: 10.1161/HYPERTENSIONAHA.111.00020. Epub 2013 Mar 25.


Conditional expression of Pomc in the Lepr-positive subpopulation of POMC neurons is sufficient for normal energy homeostasis and metabolism.

Lam DD, Attard CA, Mercer AJ, Myers MG Jr, Rubinstein M, Low MJ.

Endocrinology. 2015 Apr;156(4):1292-302. doi: 10.1210/en.2014-1373. Epub 2015 Jan 16.


Leptin indirectly regulates gonadotropin-releasing hormone neuronal function.

Quennell JH, Mulligan AC, Tups A, Liu X, Phipps SJ, Kemp CJ, Herbison AE, Grattan DR, Anderson GM.

Endocrinology. 2009 Jun;150(6):2805-12. doi: 10.1210/en.2008-1693. Epub 2009 Jan 29.


CCK stimulation of GLP-1 neurons involves α1-adrenoceptor-mediated increase in glutamatergic synaptic inputs.

Hisadome K, Reimann F, Gribble FM, Trapp S.

Diabetes. 2011 Nov;60(11):2701-9. doi: 10.2337/db11-0489. Epub 2011 Sep 1.


Partial ablation of leptin signaling in mouse pancreatic α-cells does not alter either glucose or lipid homeostasis.

Tudurí E, Denroche HC, Kara JA, Asadi A, Fox JK, Kieffer TJ.

Am J Physiol Endocrinol Metab. 2014 Apr 1;306(7):E748-55. doi: 10.1152/ajpendo.00681.2013. Epub 2014 Jan 28.

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