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Items: 1 to 20 of 93

1.

An assessment of the impact of physico-chemical and biochemical characteristics on the human kinetic adjustment factor for systemic toxicants.

Valcke M, Krishnan K.

Toxicology. 2011 Aug 15;286(1-3):36-47. doi: 10.1016/j.tox.2011.05.003. Epub 2011 May 14.

PMID:
21605617
2.

Evaluation of the impact of the exposure route on the human kinetic adjustment factor.

Valcke M, Krishnan K.

Regul Toxicol Pharmacol. 2011 Mar;59(2):258-69. doi: 10.1016/j.yrtph.2010.10.008. Epub 2010 Oct 20.

PMID:
20969910
3.

Assessing the impact of child/adult differences in hepatic first-pass effect on the human kinetic adjustment factor for ingested toxicants.

Valcke M, Krishnan K.

Regul Toxicol Pharmacol. 2013 Feb;65(1):126-34. doi: 10.1016/j.yrtph.2012.11.006. Epub 2012 Nov 29.

PMID:
23200794
4.

Assessing the impact of the duration and intensity of inhalation exposure on the magnitude of the variability of internal dose metrics in children and adults.

Valcke M, Krishnan K.

Inhal Toxicol. 2011 Dec;23(14):863-77. doi: 10.3109/08958378.2011.609918. Epub 2011 Nov 15.

PMID:
22084919
5.

Characterization of the human kinetic adjustment factor for the health risk assessment of environmental contaminants.

Valcke M, Krishnan K.

J Appl Toxicol. 2014 Mar;34(3):227-40. doi: 10.1002/jat.2919. Epub 2013 Sep 13. Review.

PMID:
24038072
6.
7.

Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.

Nong A, McCarver DG, Hines RN, Krishnan K.

Toxicol Appl Pharmacol. 2006 Jul 1;214(1):78-87. Epub 2006 Feb 7.

PMID:
16464483
8.
9.
10.
11.

Probabilistic framework for the estimation of the adult and child toxicokinetic intraspecies uncertainty factors.

Pelekis M, Nicolich MJ, Gauthier JS.

Risk Anal. 2003 Dec;23(6):1239-55.

PMID:
14641898
13.

An assessment of the interindividual variability of internal dosimetry during multi-route exposure to drinking water contaminants.

Valcke M, Krishnan K.

Int J Environ Res Public Health. 2010 Nov;7(11):4002-22. doi: 10.3390/ijerph7114002. Epub 2010 Nov 17.

14.

Dosimetric adjustments for interspecies extrapolation of inhaled poorly soluble particles (PSP).

Jarabek AM, Asgharian B, Miller FJ.

Inhal Toxicol. 2005 Jun-Jul;17(7-8):317-34.

PMID:
16020031
15.

Determination of a site-specific reference dose for methylmercury for fish-eating populations.

Shipp AM, Gentry PR, Lawrence G, Van Landingham C, Covington T, Clewell HJ, Gribben K, Crump K.

Toxicol Ind Health. 2000 Nov;16(9-10):335-438. Review.

PMID:
11762928
16.

Metabolism, variability and risk assessment.

Dorne JL.

Toxicology. 2010 Feb 9;268(3):156-64. doi: 10.1016/j.tox.2009.11.004. Epub 2009 Nov 20. Review.

PMID:
19932147
17.

Approaches for evaluating the relevance of multiroute exposures in establishing guideline values for drinking water contaminants.

Krishnan K, Carrier R.

J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2008 Jul-Sep;26(3):300-16. doi: 10.1080/10590500802343974. Review.

PMID:
18781539
18.
19.

Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants.

Ginsberg G, Hattis D, Sonawane B.

Toxicol Appl Pharmacol. 2004 Jul 15;198(2):164-83. Review.

PMID:
15236952
20.
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