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Items: 1 to 20 of 113

1.

Mutation of the elongin C binding domain of human respiratory syncytial virus non-structural protein 1 (NS1) results in degradation of NS1 and attenuation of the virus.

Straub CP, Lau WH, Preston FM, Headlam MJ, Gorman JJ, Collins PL, Spann KM.

Virol J. 2011 May 22;8:252. doi: 10.1186/1743-422X-8-252.

2.

Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase.

Elliott J, Lynch OT, Suessmuth Y, Qian P, Boyd CR, Burrows JF, Buick R, Stevenson NJ, Touzelet O, Gadina M, Power UF, Johnston JA.

J Virol. 2007 Apr;81(7):3428-36. Epub 2007 Jan 24.

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Respiratory syncytial virus nonstructural proteins 1 and 2 are crucial pathogenic factors that modulate interferon signaling and Treg cell distribution in mice.

Yang P, Zheng J, Wang S, Liu P, Xie M, Zhao D.

Virology. 2015 Nov;485:223-32. doi: 10.1016/j.virol.2015.07.016. Epub 2015 Aug 25.

PMID:
26298859
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9.

Multiple functional domains and complexes of the two nonstructural proteins of human respiratory syncytial virus contribute to interferon suppression and cellular location.

Swedan S, Andrews J, Majumdar T, Musiyenko A, Barik S.

J Virol. 2011 Oct;85(19):10090-100. doi: 10.1128/JVI.00413-11. Epub 2011 Jul 27.

10.

Nonstructural proteins 1 and 2 of respiratory syncytial virus suppress maturation of human dendritic cells.

Munir S, Le Nouen C, Luongo C, Buchholz UJ, Collins PL, Bukreyev A.

J Virol. 2008 Sep;82(17):8780-96. doi: 10.1128/JVI.00630-08. Epub 2008 Jun 18.

13.

Differentiation of Th subsets inhibited by nonstructural proteins of respiratory syncytial virus is mediated by ubiquitination.

Qin L, Peng D, Hu C, Xiang Y, Zhou Y, Tan Y, Qin X.

PLoS One. 2014 Jul 3;9(7):e101469. doi: 10.1371/journal.pone.0101469. eCollection 2014.

14.

Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence.

Dankar SK, Wang S, Ping J, Forbes NE, Keleta L, Li Y, Brown EG.

Virol J. 2011 Jan 12;8:13. doi: 10.1186/1743-422X-8-13.

15.

The human respiratory syncytial virus nonstructural protein 1 regulates type I and type II interferon pathways.

Hastie ML, Headlam MJ, Patel NB, Bukreyev AA, Buchholz UJ, Dave KA, Norris EL, Wright CL, Spann KM, Collins PL, Gorman JJ.

Mol Cell Proteomics. 2012 May;11(5):108-27. doi: 10.1074/mcp.M111.015909. Epub 2012 Feb 8.

16.

Respiratory syncytial virus NS1 protein colocalizes with mitochondrial antiviral signaling protein MAVS following infection.

Boyapalle S, Wong T, Garay J, Teng M, San Juan-Vergara H, Mohapatra S, Mohapatra S.

PLoS One. 2012;7(2):e29386. doi: 10.1371/journal.pone.0029386. Epub 2012 Feb 27.

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Influenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30.

Dankar SK, Miranda E, Forbes NE, Pelchat M, Tavassoli A, Selman M, Ping J, Jia J, Brown EG.

Virol J. 2013 Jul 25;10:243. doi: 10.1186/1743-422X-10-243.

20.

A novel mechanism for the inhibition of interferon regulatory factor-3-dependent gene expression by human respiratory syncytial virus NS1 protein.

Ren J, Liu T, Pang L, Li K, Garofalo RP, Casola A, Bao X.

J Gen Virol. 2011 Sep;92(Pt 9):2153-9. doi: 10.1099/vir.0.032987-0. Epub 2011 Jun 1.

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