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Results: 1 to 20 of 120

1.

Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells.

Takahashi H, Chen MC, Pham H, Angst E, King JC, Park J, Brovman EY, Ishiguro H, Harris DM, Reber HA, Hines OJ, Gukovskaya AS, Go VL, Eibl G.

Biochim Biophys Acta. 2011 Aug;1813(8):1465-74. doi: 10.1016/j.bbamcr.2011.05.003. Epub 2011 May 10.

PMID:
21596068
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Wogonin induces apoptosis in RPMI 8226, a human myeloma cell line, by downregulating phospho-Akt and overexpressing Bax.

Zhang M, Liu LP, Chen Y, Tian XY, Qin J, Wang D, Li Z, Mo SL.

Life Sci. 2013 Jan 17;92(1):55-62. doi: 10.1016/j.lfs.2012.10.023. Epub 2012 Nov 8.

PMID:
23142241
[PubMed - indexed for MEDLINE]
3.

Simultaneous knock-down of Bcl-xL and Mcl-1 induces apoptosis through Bax activation in pancreatic cancer cells.

Takahashi H, Chen MC, Pham H, Matsuo Y, Ishiguro H, Reber HA, Takeyama H, Hines OJ, Eibl G.

Biochim Biophys Acta. 2013 Dec;1833(12):2980-7. doi: 10.1016/j.bbamcr.2013.08.006. Epub 2013 Aug 14.

PMID:
23954445
[PubMed - indexed for MEDLINE]
4.

Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway.

Wang CZ, Calway TD, Wen XD, Smith J, Yu C, Wang Y, Mehendale SR, Yuan CS.

Int J Oncol. 2013 Mar;42(3):1018-26. doi: 10.3892/ijo.2013.1777. Epub 2013 Jan 16.

PMID:
23337959
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells.

Huang ST, Wang CY, Yang RC, Chu CJ, Wu HT, Pang JH.

Phytomedicine. 2010 Jan;17(1):47-54. doi: 10.1016/j.phymed.2009.06.005. Epub 2009 Jul 3.

PMID:
19577445
[PubMed - indexed for MEDLINE]
6.

Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells.

Wang CZ, Li XL, Wang QF, Mehendale SR, Yuan CS.

Phytomedicine. 2010 Jan;17(1):63-8. doi: 10.1016/j.phymed.2009.07.003.

PMID:
19836937
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway.

Huang KF, Zhang GD, Huang YQ, Diao Y.

Int Immunopharmacol. 2012 Feb;12(2):334-41. doi: 10.1016/j.intimp.2011.12.004. Epub 2011 Dec 17.

PMID:
22182776
[PubMed - indexed for MEDLINE]
8.

Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis.

Leung HW, Yang WH, Lai MY, Lin CJ, Lee HZ.

Food Chem Toxicol. 2007 Mar;45(3):403-11. Epub 2006 Sep 8.

PMID:
17050058
[PubMed - indexed for MEDLINE]
9.

Wogonin, an active ingredient of Chinese herb medicine Scutellaria baicalensis, inhibits the mobility and invasion of human gallbladder carcinoma GBC-SD cells by inducing the expression of maspin.

Dong P, Zhang Y, Gu J, Wu W, Li M, Yang J, Zhang L, Lu J, Mu J, Chen L, Li S, Wang J, Liu Y.

J Ethnopharmacol. 2011 Oct 11;137(3):1373-80. doi: 10.1016/j.jep.2011.08.005. Epub 2011 Aug 6.

PMID:
21855619
[PubMed - indexed for MEDLINE]
10.

Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death.

Lee HH, Yang LL, Wang CC, Hu SY, Chang SF, Lee YH.

Brain Res. 2003 Oct 3;986(1-2):103-13.

PMID:
12965234
[PubMed - indexed for MEDLINE]
11.

Baicalein, an active component of Scutellaria baicalensis Georgi, induces apoptosis in human colon cancer cells and prevents AOM/DSS-induced colon cancer in mice.

Kim DH, Hossain MA, Kang YJ, Jang JY, Lee YJ, Im E, Yoon JH, Kim HS, Chung HY, Kim ND.

Int J Oncol. 2013 Nov;43(5):1652-8. doi: 10.3892/ijo.2013.2086. Epub 2013 Sep 4.

PMID:
24008356
[PubMed - indexed for MEDLINE]
12.

Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells.

Liu S, Ma Z, Cai H, Li Q, Rong W, Kawano M.

Eur J Haematol. 2010 Feb 1;84(2):137-44. doi: 10.1111/j.1600-0609.2009.01365.x. Epub 2009 Oct 28.

PMID:
19878271
[PubMed - indexed for MEDLINE]
13.

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease.

Lee WR, Shen SC, Lin HY, Hou WC, Yang LL, Chen YC.

Biochem Pharmacol. 2002 Jan 15;63(2):225-36.

PMID:
11841797
[PubMed - indexed for MEDLINE]
14.

Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell.

Himeji M, Ohtsuki T, Fukazawa H, Tanaka M, Yazaki S, Ui S, Nishio K, Yamamoto H, Tasaka K, Mimura A.

Cancer Lett. 2007 Jan 8;245(1-2):269-74. Epub 2006 Feb 23.

PMID:
16497434
[PubMed - indexed for MEDLINE]
15.

Mitochondrial-dependent caspase activation pathway is involved in baicalein-induced apoptosis in human hepatoma J5 cells.

Kuo HM, Tsai HC, Lin YL, Yang JS, Huang AC, Yang MD, Hsu SC, Chung MC, Gibson Wood W, Chung JG.

Int J Oncol. 2009 Oct;35(4):717-24.

PMID:
19724907
[PubMed - indexed for MEDLINE]
16.

[Baicalein selectively induce apoptosis in human leukemia K562 cells].

Dong QH, Zheng S, Xu RZ, Lü QH.

Yao Xue Xue Bao. 2003 Nov;38(11):817-20. Chinese.

PMID:
14991992
[PubMed - indexed for MEDLINE]
17.

Flavone-catalyzed apoptosis in Scutellaria baicalensis.

Hirunuma M, Shoyama Y, Sasaki K, Sakamoto S, Taura F, Shoyama Y, Tanaka H, Morimoto S.

Phytochemistry. 2011 Jun;72(8):752-60. doi: 10.1016/j.phytochem.2011.02.009. Epub 2011 Mar 4.

PMID:
21377703
[PubMed - indexed for MEDLINE]
18.

Beneficial effect of flavonoid baicalein in cisplatin-induced cell death of human glioma cells.

Lee SW, Song GS, Kwon CH, Kim YK.

Neurosci Lett. 2005 Jul 1-8;382(1-2):71-5. Epub 2005 Mar 21.

PMID:
15911124
[PubMed - indexed for MEDLINE]
19.

The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells.

Zhou QM, Wang S, Zhang H, Lu YY, Wang XF, Motoo Y, Su SB.

Acta Pharmacol Sin. 2009 Dec;30(12):1648-58. doi: 10.1038/aps.2009.166.

PMID:
19960010
[PubMed - indexed for MEDLINE]
Free Article
20.

Reevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na⁺/K⁺-ATPase α3 subunit-involved mitochondrial stress and amplification of caspase cascades.

Chan SH, Leu WJ, Hsu LC, Chang HS, Hwang TL, Chen IS, Chen CS, Guh JH.

Biochem Pharmacol. 2013 Dec 1;86(11):1564-75. doi: 10.1016/j.bcp.2013.09.021. Epub 2013 Oct 4.

PMID:
24099795
[PubMed - indexed for MEDLINE]

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