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Items: 1 to 20 of 126

1.

Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells.

McHugh D, Page J, Dunn E, Bradshaw HB.

Br J Pharmacol. 2012 Apr;165(8):2414-24. doi: 10.1111/j.1476-5381.2011.01497.x.

2.

Activation of GPR18 by cannabinoid compounds: a tale of biased agonism.

Console-Bram L, Brailoiu E, Brailoiu GC, Sharir H, Abood ME.

Br J Pharmacol. 2014 Aug;171(16):3908-17. doi: 10.1111/bph.12746.

3.

N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor.

McHugh D, Hu SS, Rimmerman N, Juknat A, Vogel Z, Walker JM, Bradshaw HB.

BMC Neurosci. 2010 Mar 26;11:44. doi: 10.1186/1471-2202-11-44.

4.

So what do we call GPR18 now?

Alexander SP.

Br J Pharmacol. 2012 Apr;165(8):2411-3. doi: 10.1111/j.1476-5381.2011.01731.x.

5.

A GPR18-based signalling system regulates IOP in murine eye.

Caldwell MD, Hu SS, Viswanathan S, Bradshaw H, Kelly ME, Straiker A.

Br J Pharmacol. 2013 Jun;169(4):834-43. doi: 10.1111/bph.12136.

6.

Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.

Straiker A, Wager-Miller J, Hutchens J, Mackie K.

Br J Pharmacol. 2012 Apr;165(8):2660-71. doi: 10.1111/j.1476-5381.2011.01744.x.

7.

N-Arachidonyl glycine does not activate G protein-coupled receptor 18 signaling via canonical pathways.

Lu VB, Puhl HL 3rd, Ikeda SR.

Mol Pharmacol. 2013 Jan;83(1):267-82. doi: 10.1124/mol.112.081182. Epub 2012 Oct 25.

8.

Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro.

Whyte LS, Ford L, Ridge SA, Cameron GA, Rogers MJ, Ross RA.

Br J Pharmacol. 2012 Apr;165(8):2584-97. doi: 10.1111/j.1476-5381.2011.01519.x.

9.

GPR18 in microglia: implications for the CNS and endocannabinoid system signalling.

McHugh D.

Br J Pharmacol. 2012 Dec;167(8):1575-82. doi: 10.1111/j.1476-5381.2012.02019.x. Review.

10.

N-arachidonoyl glycine induces macrophage apoptosis via GPR18.

Takenouchi R, Inoue K, Kambe Y, Miyata A.

Biochem Biophys Res Commun. 2012 Feb 10;418(2):366-71. doi: 10.1016/j.bbrc.2012.01.027. Epub 2012 Jan 11.

PMID:
22266325
11.

Cannabinoid and lipid-mediated vasorelaxation in retinal microvasculature.

MacIntyre J, Dong A, Straiker A, Zhu J, Howlett SE, Bagher A, Denovan-Wright E, Yu DY, Kelly ME.

Eur J Pharmacol. 2014 Jul 15;735:105-14. doi: 10.1016/j.ejphar.2014.03.055. Epub 2014 Apr 18.

PMID:
24751709
12.

siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates N-arachidonoyl glycine-induced cell migration.

McHugh D, Wager-Miller J, Page J, Bradshaw HB.

J Mol Signal. 2012 Jul 26;7(1):10. doi: 10.1186/1750-2187-7-10.

13.

Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity.

Morgan DJ, Muller CH, Murataeva NA, Davis BJ, Mackie K.

Br J Pharmacol. 2012 Apr;165(8):2575-83. doi: 10.1111/j.1476-5381.2011.01506.x.

14.

Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors.

Bátkai S, Mukhopadhyay P, Horváth B, Rajesh M, Gao RY, Mahadevan A, Amere M, Battista N, Lichtman AH, Gauson LA, Maccarrone M, Pertwee RG, Pacher P.

Br J Pharmacol. 2012 Apr;165(8):2450-61. doi: 10.1111/j.1476-5381.2011.01410.x.

15.

Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability.

Alhamoruni A, Wright KL, Larvin M, O'Sullivan SE.

Br J Pharmacol. 2012 Apr;165(8):2598-610. doi: 10.1111/j.1476-5381.2011.01589.x.

16.

Compartmentalization of endocannabinoids into lipid rafts in a microglial cell line devoid of caveolin-1.

Rimmerman N, Bradshaw HB, Kozela E, Levy R, Juknat A, Vogel Z.

Br J Pharmacol. 2012 Apr;165(8):2436-49. doi: 10.1111/j.1476-5381.2011.01380.x.

17.

The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats.

Scherma M, Justinová Z, Zanettini C, Panlilio LV, Mascia P, Fadda P, Fratta W, Makriyannis A, Vadivel SK, Gamaleddin I, Le Foll B, Goldberg SR.

Br J Pharmacol. 2012 Apr;165(8):2539-48. doi: 10.1111/j.1476-5381.2011.01467.x.

18.

Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells.

Juknat A, Pietr M, Kozela E, Rimmerman N, Levy R, Coppola G, Geschwind D, Vogel Z.

Br J Pharmacol. 2012 Apr;165(8):2512-28. doi: 10.1111/j.1476-5381.2011.01461.x.

19.

The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice.

Booker L, Kinsey SG, Abdullah RA, Blankman JL, Long JZ, Ezzili C, Boger DL, Cravatt BF, Lichtman AH.

Br J Pharmacol. 2012 Apr;165(8):2485-96. doi: 10.1111/j.1476-5381.2011.01445.x.

20.

Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18.

Kohno M, Hasegawa H, Inoue A, Muraoka M, Miyazaki T, Oka K, Yasukawa M.

Biochem Biophys Res Commun. 2006 Sep 1;347(3):827-32. Epub 2006 Jul 10.

PMID:
16844083
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