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Results: 1 to 20 of 138

1.

The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways.

Tisoncik JR, Billharz R, Burmakina S, Belisle SE, Proll SC, Korth MJ, García-Sastre A, Katze MG.

J Gen Virol. 2011 Sep;92(Pt 9):2093-104. doi: 10.1099/vir.0.032060-0. Epub 2011 May 18. Erratum in: J Gen Virol. 2011 Oct;92(Pt 10):2466. Garcíia-Sastre, Adolfo [corrected to García-Sastre, Adolfo].

PMID:
21593271
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Alleles A and B of non-structural protein 1 of avian influenza A viruses differentially inhibit beta interferon production in human and mink lung cells.

Munir M, Zohari S, Metreveli G, Baule C, Belák S, Berg M.

J Gen Virol. 2011 Sep;92(Pt 9):2111-21. doi: 10.1099/vir.0.031716-0. Epub 2011 Jun 1.

PMID:
21632557
[PubMed - indexed for MEDLINE]
Free Article
3.

Multiple anti-interferon actions of the influenza A virus NS1 protein.

Kochs G, García-Sastre A, Martínez-Sobrido L.

J Virol. 2007 Jul;81(13):7011-21. Epub 2007 Apr 18.

PMID:
17442719
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza.

Geiss GK, Salvatore M, Tumpey TM, Carter VS, Wang X, Basler CF, Taubenberger JK, Bumgarner RE, Palese P, Katze MG, García-Sastre A.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10736-41. Epub 2002 Jul 29.

PMID:
12149435
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon.

Wang X, Li M, Zheng H, Muster T, Palese P, Beg AA, García-Sastre A.

J Virol. 2000 Dec;74(24):11566-73.

PMID:
11090154
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells.

Haye K, Burmakina S, Moran T, García-Sastre A, Fernandez-Sesma A.

J Virol. 2009 Jul;83(13):6849-62. doi: 10.1128/JVI.02323-08. Epub 2009 Apr 29.

PMID:
19403682
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways.

Billharz R, Zeng H, Proll SC, Korth MJ, Lederer S, Albrecht R, Goodman AG, Rosenzweig E, Tumpey TM, García-Sastre A, Katze MG.

J Virol. 2009 Oct;83(20):10557-70. doi: 10.1128/JVI.00330-09. Epub 2009 Aug 12.

PMID:
19706713
[PubMed - indexed for MEDLINE]
Free PMC Article
8.
9.

Influenza A virus-encoded NS1 virulence factor protein inhibits innate immune response by targeting IKK.

Gao S, Song L, Li J, Zhang Z, Peng H, Jiang W, Wang Q, Kang T, Chen S, Huang W.

Cell Microbiol. 2012 Dec;14(12):1849-66. doi: 10.1111/cmi.12005. Epub 2012 Sep 17.

PMID:
22891964
[PubMed - indexed for MEDLINE]
10.

The N- and C-terminal domains of the NS1 protein of influenza B virus can independently inhibit IRF-3 and beta interferon promoter activation.

Donelan NR, Dauber B, Wang X, Basler CF, Wolff T, García-Sastre A.

J Virol. 2004 Nov;78(21):11574-82.

PMID:
15479798
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence.

Dankar SK, Wang S, Ping J, Forbes NE, Keleta L, Li Y, Brown EG.

Virol J. 2011 Jan 12;8:13. doi: 10.1186/1743-422X-8-13.

PMID:
21226922
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs.

Solórzano A, Webby RJ, Lager KM, Janke BH, García-Sastre A, Richt JA.

J Virol. 2005 Jun;79(12):7535-43.

PMID:
15919908
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Influenza virus evades innate and adaptive immunity via the NS1 protein.

Fernandez-Sesma A, Marukian S, Ebersole BJ, Kaminski D, Park MS, Yuen T, Sealfon SC, García-Sastre A, Moran TM.

J Virol. 2006 Jul;80(13):6295-304.

PMID:
16775317
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling.

Jia D, Rahbar R, Chan RW, Lee SM, Chan MC, Wang BX, Baker DP, Sun B, Peiris JS, Nicholls JM, Fish EN.

PLoS One. 2010 Nov 10;5(11):e13927. doi: 10.1371/journal.pone.0013927.

PMID:
21085662
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Inhibition of host innate immune responses and pathogenicity of recombinant Newcastle disease viruses expressing NS1 genes of influenza A viruses.

Kim SH, Samal SK.

J Gen Virol. 2010 Aug;91(Pt 8):1996-2001. doi: 10.1099/vir.0.021766-0. Epub 2010 Apr 21.

PMID:
20410312
[PubMed - indexed for MEDLINE]
Free Article
16.

Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein.

Hale BG, Steel J, Medina RA, Manicassamy B, Ye J, Hickman D, Hai R, Schmolke M, Lowen AC, Perez DR, García-Sastre A.

J Virol. 2010 Jul;84(14):6909-22. doi: 10.1128/JVI.00081-10. Epub 2010 May 5.

PMID:
20444891
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains.

Wang X, Basler CF, Williams BR, Silverman RH, Palese P, García-Sastre A.

J Virol. 2002 Dec;76(24):12951-62.

PMID:
12438621
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Influenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30.

Dankar SK, Miranda E, Forbes NE, Pelchat M, Tavassoli A, Selman M, Ping J, Jia J, Brown EG.

Virol J. 2013 Jul 25;10:243. doi: 10.1186/1743-422X-10-243.

PMID:
23886034
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The non-structural (NS) gene segment of H9N2 influenza virus isolated from backyard poultry in Pakistan reveals strong genetic and functional similarities to the NS gene of highly pathogenic H5N1.

Munir M, Zohari S, Iqbal M, Abbas M, Perez DR, Berg M.

Virulence. 2013 Oct 1;4(7):612-23. doi: 10.4161/viru.26055. Epub 2013 Aug 13.

PMID:
23959028
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Strong interferon-inducing capacity of a highly virulent variant of influenza A virus strain PR8 with deletions in the NS1 gene.

Kochs G, Martínez-Sobrido L, Lienenklaus S, Weiss S, García-Sastre A, Staeheli P.

J Gen Virol. 2009 Dec;90(Pt 12):2990-4. doi: 10.1099/vir.0.015727-0. Epub 2009 Sep 2.

PMID:
19726611
[PubMed - indexed for MEDLINE]
Free PMC Article

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