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Results: 1 to 20 of 101

1.

Somatic hypermutation targeting is influenced by location within the immunoglobulin V region.

Cohen RM, Kleinstein SH, Louzoun Y.

Mol Immunol. 2011 Jul;48(12-13):1477-83. doi: 10.1016/j.molimm.2011.04.002. Epub 2011 May 18.

PMID:
21592579
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Ongoing somatic hypermutation of the rearranged VH but not of the V-lambda gene in EBV-transformed rheumatoid factor-producing lymphoblastoid cell line.

Chezar I, Lobel-Lavi L, Steinitz M, Laskov R.

Mol Immunol. 2008 Nov;46(1):80-90. doi: 10.1016/j.molimm.2008.07.002. Epub 2008 Aug 20.

PMID:
18718665
[PubMed - indexed for MEDLINE]
3.

Evolution of Ig DNA sequence to target specific base positions within codons for somatic hypermutation.

Shapiro GS, Aviszus K, Murphy J, Wysocki LJ.

J Immunol. 2002 Mar 1;168(5):2302-6.

PMID:
11859119
[PubMed - indexed for MEDLINE]
Free Article
4.

Identification of core DNA elements that target somatic hypermutation.

Kohler KM, McDonald JJ, Duke JL, Arakawa H, Tan S, Kleinstein SH, Buerstedde JM, Schatz DG.

J Immunol. 2012 Dec 1;189(11):5314-26. doi: 10.4049/jimmunol.1202082. Epub 2012 Oct 19.

PMID:
23087403
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Recombinase-mediated cassette exchange as a novel method to study somatic hypermutation in Ramos cells.

Baughn LB, Kalis SL, MacCarthy T, Wei L, Fan M, Bergman A, Scharff MD.

MBio. 2011 Oct 11;2(5). pii: e00186-11. doi: 10.1128/mBio.00186-11. Print 2011.

PMID:
21990614
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Somatic diversification and selection of immunoglobulin heavy and light chain variable region genes in IgG+ CD5+ chronic lymphocytic leukemia B cells.

Hashimoto S, Dono M, Wakai M, Allen SL, Lichtman SM, Schulman P, Vinciguerra VP, Ferrarini M, Silver J, Chiorazzi N.

J Exp Med. 1995 Apr 1;181(4):1507-17.

PMID:
7535340
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation.

Zan H, Cerutti A, Dramitinos P, Schaffer A, Li Z, Casali P.

J Immunol. 1999 Mar 15;162(6):3437-47.

PMID:
10092799
[PubMed - indexed for MEDLINE]
Free Article
8.

Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes.

Wilson PC, de Bouteiller O, Liu YJ, Potter K, Banchereau J, Capra JD, Pascual V.

J Exp Med. 1998 Jan 5;187(1):59-70.

PMID:
9419211
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The pattern and distribution of immunoglobulin VH gene mutations in chronic lymphocytic leukemia B cells are consistent with the canonical somatic hypermutation process.

Messmer BT, Albesiano E, Messmer D, Chiorazzi N.

Blood. 2004 May 1;103(9):3490-5. Epub 2003 Dec 24.

PMID:
14695232
[PubMed - indexed for MEDLINE]
Free Article
10.

The nucleotide targets of somatic mutation and the role of selection in immunoglobulin heavy chains of a teleost fish.

Yang F, Waldbieser GC, Lobb CJ.

J Immunol. 2006 Feb 1;176(3):1655-67.

PMID:
16424195
[PubMed - indexed for MEDLINE]
Free Article
11.

Intricate targeting of immunoglobulin somatic hypermutation maximizes the efficiency of affinity maturation.

Zheng NY, Wilson K, Jared M, Wilson PC.

J Exp Med. 2005 May 2;201(9):1467-78.

PMID:
15867095
[PubMed - indexed for MEDLINE]
Free PMC Article
12.
13.

Somatic hypermutation of the AID transgene in B and non-B cells.

Martin A, Scharff MD.

Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12304-8. Epub 2002 Aug 29.

PMID:
12202747
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Improved methods for detecting selection by mutation analysis of Ig V region sequences.

Hershberg U, Uduman M, Shlomchik MJ, Kleinstein SH.

Int Immunol. 2008 May;20(5):683-94. doi: 10.1093/intimm/dxn026. Epub 2008 Apr 7.

PMID:
18397909
[PubMed - indexed for MEDLINE]
Free Article
15.
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17.

AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells.

Gramlich HS, Reisbig T, Schatz DG.

PLoS One. 2012;7(6):e39601. doi: 10.1371/journal.pone.0039601. Epub 2012 Jun 29.

PMID:
22768095
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Base-specific sequences that bias somatic hypermutation deduced by analysis of out-of-frame human IgVH genes.

Dunn-Walters DK, Dogan A, Boursier L, MacDonald CM, Spencer J.

J Immunol. 1998 Mar 1;160(5):2360-4.

PMID:
9498777
[PubMed - indexed for MEDLINE]
Free Article
19.

Imprint of somatic hypermutation differs in human immunoglobulin heavy and lambda chain variable gene segments.

Boursier L, Su W, Spencer J.

Mol Immunol. 2003 Jun;39(16):1025-34.

PMID:
12749909
[PubMed - indexed for MEDLINE]
20.

Facultative role of germinal centers and T cells in the somatic diversification of IgVH genes.

Miller C, Stedra J, Kelsoe G, Cerny J.

J Exp Med. 1995 Apr 1;181(4):1319-31.

PMID:
7535332
[PubMed - indexed for MEDLINE]
Free PMC Article

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