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Items: 1 to 20 of 127

1.

Network-based tools for the identification of novel drug targets.

Farkas IJ, Korcsmáros T, Kovács IA, Mihalik Á, Palotai R, Simkó GI, Szalay KZ, Szalay-Beko M, Vellai T, Wang S, Csermely P.

Sci Signal. 2011 May 17;4(173):pt3. doi: 10.1126/scisignal.2001950.

PMID:
21586727
2.

Chaperones as integrators of cellular networks: changes of cellular integrity in stress and diseases.

Palotai R, Szalay MS, Csermely P.

IUBMB Life. 2008 Jan;60(1):10-8. doi: 10.1002/iub.8. Review.

3.

The analysis of the drug-targets based on the topological properties in the human protein-protein interaction network.

Zhu M, Gao L, Li X, Liu Z, Xu C, Yan Y, Walker E, Jiang W, Su B, Chen X, Lin H.

J Drug Target. 2009 Aug;17(7):524-32. doi: 10.1080/10611860903046610.

PMID:
19530902
4.

The protein network as a tool for finding novel drug targets.

Strong M, Eisenberg D.

Prog Drug Res. 2007;64:191, 193-215. Review.

PMID:
17195476
5.

[Development of antituberculous drugs: current status and future prospects].

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID:
17240921
6.

Signalogs: orthology-based identification of novel signaling pathway components in three metazoans.

Korcsmáros T, Szalay MS, Rovó P, Palotai R, Fazekas D, Lenti K, Farkas IJ, Csermely P, Vellai T.

PLoS One. 2011 May 3;6(5):e19240. doi: 10.1371/journal.pone.0019240.

7.

The use of Gene Ontology terms for predicting highly-connected 'hub' nodes in protein-protein interaction networks.

Hsing M, Byler KG, Cherkasov A.

BMC Syst Biol. 2008 Sep 16;2:80. doi: 10.1186/1752-0509-2-80.

8.

SignaLink 2 - a signaling pathway resource with multi-layered regulatory networks.

Fazekas D, Koltai M, Türei D, Módos D, Pálfy M, Dúl Z, Zsákai L, Szalay-Bekő M, Lenti K, Farkas IJ, Vellai T, Csermely P, Korcsmáros T.

BMC Syst Biol. 2013 Jan 18;7:7. doi: 10.1186/1752-0509-7-7.

9.

What does systems biology mean for drug development?

Schrattenholz A, Soskić V.

Curr Med Chem. 2008;15(15):1520-8. Review.

PMID:
18537627
10.

Systems biology approaches and tools for analysis of interactomes and multi-target drugs.

Schrattenholz A, Groebe K, Soskic V.

Methods Mol Biol. 2010;662:29-58. doi: 10.1007/978-1-60761-800-3_2. Review.

PMID:
20824465
11.
12.

Predicting new molecular targets for rhein using network pharmacology.

Zhang A, Sun H, Yang B, Wang X.

BMC Syst Biol. 2012 Mar 21;6:20. doi: 10.1186/1752-0509-6-20. Retraction in: Zhang A, Sun H, Yang B, Wang X. BMC Syst Biol. 2014;8:105.

13.

Drug target identification in sphingolipid metabolism by computational systems biology tools: metabolic control analysis and metabolic pathway analysis.

Ozbayraktar FB, Ulgen KO.

J Biomed Inform. 2010 Aug;43(4):537-49. doi: 10.1016/j.jbi.2010.03.006. Epub 2010 Mar 27.

14.

Defining a modular signalling network from the fly interactome.

Baudot A, Angelelli JB, Guénoche A, Jacq B, Brun C.

BMC Syst Biol. 2008 May 19;2:45. doi: 10.1186/1752-0509-2-45.

15.

PDTD: a web-accessible protein database for drug target identification.

Gao Z, Li H, Zhang H, Liu X, Kang L, Luo X, Zhu W, Chen K, Wang X, Jiang H.

BMC Bioinformatics. 2008 Feb 19;9:104. doi: 10.1186/1471-2105-9-104.

16.

Identifying unexpected therapeutic targets via chemical-protein interactome.

Yang L, Chen J, Shi L, Hudock MP, Wang K, He L.

PLoS One. 2010 Mar 8;5(3):e9568. doi: 10.1371/journal.pone.0009568.

17.

Identification of information flow-modulating drug targets: a novel bridging paradigm for drug discovery.

Hwang WC, Zhang A, Ramanathan M.

Clin Pharmacol Ther. 2008 Nov;84(5):563-72. doi: 10.1038/clpt.2008.129. Epub 2008 Jul 9.

PMID:
18615007
18.

Drug effects viewed from a signal transduction network perspective.

Fliri AF, Loging WT, Volkmann RA.

J Med Chem. 2009 Dec 24;52(24):8038-46. doi: 10.1021/jm901001p.

PMID:
19891439
19.

Interaction networks: from protein functions to drug discovery. A review.

Chautard E, Thierry-Mieg N, Ricard-Blum S.

Pathol Biol (Paris). 2009 Jun;57(4):324-33. doi: 10.1016/j.patbio.2008.10.004. Epub 2008 Dec 13. Review.

PMID:
19070972
20.

[Prediction of network drug target based on improved model of bipartite graph valuation].

Liu X, Lu P, Zuo X, Chen J, Yang H, Yang Y, Gao Y.

Zhongguo Zhong Yao Za Zhi. 2012 Jan;37(2):125-9. Chinese.

PMID:
22737836
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