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Items: 1 to 20 of 134

1.

Bcl-2: a prime regulator of mitochondrial redox metabolism in cancer cells.

Low IC, Kang J, Pervaiz S.

Antioxid Redox Signal. 2011 Dec 15;15(12):2975-87. doi: 10.1089/ars.2010.3851. Epub 2011 Jul 12. Review.

PMID:
21574773
2.

Hsp90 inhibition by PU-H71 induces apoptosis through endoplasmic reticulum stress and mitochondrial pathway in cancer cells and overcomes the resistance conferred by Bcl-2.

Gallerne C, Prola A, Lemaire C.

Biochim Biophys Acta. 2013 Jun;1833(6):1356-66. doi: 10.1016/j.bbamcr.2013.02.014. Epub 2013 Feb 26.

3.

BCL-2: pro-or anti-oxidant?

Chen ZX, Pervaiz S.

Front Biosci (Elite Ed). 2009 Jun 1;1:263-8. Review.

PMID:
19482643
4.

Regulation of mitochondrial metabolism: yet another facet in the biology of the oncoprotein Bcl-2.

Krishna S, Low IC, Pervaiz S.

Biochem J. 2011 May 1;435(3):545-51. doi: 10.1042/BJ20101996. Review.

PMID:
21486225
5.

Modulating mitochondria-mediated apoptotic cell death through targeting of Bcl-2 family proteins.

Aouacheria A, Cibiel A, Guillemin Y, Gillet G, Lalle P.

Recent Pat DNA Gene Seq. 2007;1(1):43-61. Review.

PMID:
19075918
6.

Larger than life: Mitochondria and the Bcl-2 family.

Skommer J, Wlodkowic D, Deptala A.

Leuk Res. 2007 Mar;31(3):277-86. Epub 2006 Sep 5. Review.

PMID:
16911824
7.

Modulation of mitochondrial apoptosis by PI3K inhibitors.

Fulda S.

Mitochondrion. 2013 May;13(3):195-8. doi: 10.1016/j.mito.2012.05.001. Epub 2012 May 10. Review.

PMID:
22580303
8.

Deregulation of the mitochondrial apoptotic machinery and development of molecular targeted drugs in acute myeloid leukemia.

Del Poeta G, Bruno A, Del Principe MI, Venditti A, Maurillo L, Buccisano F, Stasi R, Neri B, Luciano F, Siniscalchi A, de Fabritiis P, Amadori S.

Curr Cancer Drug Targets. 2008 May;8(3):207-22. Review.

PMID:
18473734
9.

Addition of anticancer agents enhances freezing-induced prostate cancer cell death: implications of mitochondrial involvement.

Clarke DM, Baust JM, Van Buskirk RG, Baust JG.

Cryobiology. 2004 Aug;49(1):45-61.

PMID:
15265716
10.

The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability.

Harris MH, Thompson CB.

Cell Death Differ. 2000 Dec;7(12):1182-91. Review.

11.

The voltage-dependent anion channel (VDAC): function in intracellular signalling, cell life and cell death.

Shoshan-Barmatz V, Israelson A, Brdiczka D, Sheu SS.

Curr Pharm Des. 2006;12(18):2249-70. Review.

PMID:
16787253
12.

PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2 proteins and enhanced mitochondrial apoptosis.

Bender A, Opel D, Naumann I, Kappler R, Friedman L, von Schweinitz D, Debatin KM, Fulda S.

Oncogene. 2011 Jan 27;30(4):494-503. doi: 10.1038/onc.2010.429. Epub 2010 Sep 20.

PMID:
20856197
14.

The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.

Kang YH, Lee SJ.

J Cell Physiol. 2008 Oct;217(1):23-33. doi: 10.1002/jcp.21470.

PMID:
18412143
15.
16.

Fusarial toxin-induced toxicity in cultured cells and in isolated mitochondria involves PTPC-dependent activation of the mitochondrial pathway of apoptosis.

Bouaziz C, Martel C, Sharaf el dein O, Abid-Essefi S, Brenner C, Lemaire C, Bacha H.

Toxicol Sci. 2009 Aug;110(2):363-75. doi: 10.1093/toxsci/kfp117. Epub 2009 Jun 18.

17.

BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins.

Weber A, Paschen SA, Heger K, Wilfling F, Frankenberg T, Bauerschmitt H, Seiffert BM, Kirschnek S, Wagner H, Häcker G.

J Cell Biol. 2007 May 21;177(4):625-36.

18.

Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer.

Wesarg E, Hoffarth S, Wiewrodt R, Kröll M, Biesterfeld S, Huber C, Schuler M.

Int J Cancer. 2007 Dec 1;121(11):2387-94.

19.

Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis.

Schniewind B, Christgen M, Kurdow R, Haye S, Kremer B, Kalthoff H, Ungefroren H.

Int J Cancer. 2004 Mar 20;109(2):182-8.

20.
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