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Results: 1 to 20 of 135

1.

Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis.

Lippens S, Lefebvre S, Gilbert B, Sze M, Devos M, Verhelst K, Vereecke L, Mc Guire C, Guérin C, Vandenabeele P, Pasparakis M, Mikkola ML, Beyaert R, Declercq W, van Loo G.

Cell Death Differ. 2011 Dec;18(12):1845-53. doi: 10.1038/cdd.2011.55. Epub 2011 May 13.

PMID:
21566665
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth.

Schmidt-Ullrich R, Tobin DJ, Lenhard D, Schneider P, Paus R, Scheidereit C.

Development. 2006 Mar;133(6):1045-57. Epub 2006 Feb 15.

PMID:
16481354
[PubMed - indexed for MEDLINE]
Free Article
3.

Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes.

Fliniaux I, Mikkola ML, Lefebvre S, Thesleff I.

Dev Biol. 2008 Aug 1;320(1):60-71. doi: 10.1016/j.ydbio.2008.04.023. Epub 2008 Apr 26.

PMID:
18508042
[PubMed - indexed for MEDLINE]
Free Article
4.

A20 (TNFAIP3) alleviates CVB3-induced myocarditis via inhibiting NF-κB signaling.

Gui J, Yue Y, Chen R, Xu W, Xiong S.

PLoS One. 2012;7(9):e46515. doi: 10.1371/journal.pone.0046515. Epub 2012 Sep 28.

PMID:
23029542
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Deubiquitinating enzyme A20 negatively regulates NF-κB signaling in skeletal muscle in mdx mice.

Charan RA, Hanson R, Clemens PR.

FASEB J. 2012 Feb;26(2):587-95. doi: 10.1096/fj.11-189829. Epub 2011 Oct 19. Erratum in: FASEB J. 2013 Jan;27(1):410.

PMID:
22012122
[PubMed - indexed for MEDLINE]
Free Article
6.

Aggravation of post-ischemic liver injury by overexpression of A20, an NF-κB suppressor.

Yu J, Lee HS, Lee SM, Yu HC, Moon WS, Chung MJ, Park JW, Park BH.

J Hepatol. 2011 Aug;55(2):328-36. doi: 10.1016/j.jhep.2010.11.029. Epub 2010 Dec 15.

PMID:
21167234
[PubMed - indexed for MEDLINE]
7.

Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development.

Pispa J, Pummila M, Barker PA, Thesleff I, Mikkola ML.

Hum Mol Genet. 2008 Nov 1;17(21):3380-91. doi: 10.1093/hmg/ddn232. Epub 2008 Aug 9.

PMID:
18689798
[PubMed - indexed for MEDLINE]
Free Article
8.

Identification of ectodysplasin target genes reveals the involvement of chemokines in hair development.

Lefebvre S, Fliniaux I, Schneider P, Mikkola ML.

J Invest Dermatol. 2012 Apr;132(4):1094-102. doi: 10.1038/jid.2011.453. Epub 2012 Jan 26.

PMID:
22277947
[PubMed - indexed for MEDLINE]
Free Article
9.

Frequent inactivation of A20 in B-cell lymphomas.

Kato M, Sanada M, Kato I, Sato Y, Takita J, Takeuchi K, Niwa A, Chen Y, Nakazaki K, Nomoto J, Asakura Y, Muto S, Tamura A, Iio M, Akatsuka Y, Hayashi Y, Mori H, Igarashi T, Kurokawa M, Chiba S, Mori S, Ishikawa Y, Okamoto K, Tobinai K, Nakagama H, Nakahata T, Yoshino T, Kobayashi Y, Ogawa S.

Nature. 2009 Jun 4;459(7247):712-6. doi: 10.1038/nature07969. Epub 2009 May 3.

PMID:
19412163
[PubMed - indexed for MEDLINE]
10.

Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression.

Pummila M, Fliniaux I, Jaatinen R, James MJ, Laurikkala J, Schneider P, Thesleff I, Mikkola ML.

Development. 2007 Jan;134(1):117-25.

PMID:
17164417
[PubMed - indexed for MEDLINE]
Free Article
11.

Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar.

Laurikkala J, Pispa J, Jung HS, Nieminen P, Mikkola M, Wang X, Saarialho-Kere U, Galceran J, Grosschedl R, Thesleff I.

Development. 2002 May;129(10):2541-53.

PMID:
11973284
[PubMed - indexed for MEDLINE]
Free Article
12.

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology.

Vereecke L, Beyaert R, van Loo G.

Trends Immunol. 2009 Aug;30(8):383-91. doi: 10.1016/j.it.2009.05.007. Epub 2009 Jul 28. Review.

PMID:
19643665
[PubMed - indexed for MEDLINE]
13.

The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN.

Heyninck K, De Valck D, Vanden Berghe W, Van Criekinge W, Contreras R, Fiers W, Haegeman G, Beyaert R.

J Cell Biol. 1999 Jun 28;145(7):1471-82.

PMID:
10385526
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Ectodysplasin receptor-mediated signaling is essential for embryonic submandibular salivary gland development.

Jaskoll T, Zhou YM, Trump G, Melnick M.

Anat Rec A Discov Mol Cell Evol Biol. 2003 Apr;271(2):322-31.

PMID:
12629675
[PubMed - indexed for MEDLINE]
Free Article
15.

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice.

Chu Y, Vahl JC, Kumar D, Heger K, Bertossi A, Wójtowicz E, Soberon V, Schenten D, Mack B, Reutelshöfer M, Beyaert R, Amann K, van Loo G, Schmidt-Supprian M.

Blood. 2011 Feb 17;117(7):2227-36. doi: 10.1182/blood-2010-09-306019. Epub 2010 Nov 18.

PMID:
21088135
[PubMed - indexed for MEDLINE]
Free Article
16.

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.

Matmati M, Jacques P, Maelfait J, Verheugen E, Kool M, Sze M, Geboes L, Louagie E, Mc Guire C, Vereecke L, Chu Y, Boon L, Staelens S, Matthys P, Lambrecht BN, Schmidt-Supprian M, Pasparakis M, Elewaut D, Beyaert R, van Loo G.

Nat Genet. 2011 Aug 14;43(9):908-12. doi: 10.1038/ng.874.

PMID:
21841782
[PubMed - indexed for MEDLINE]
17.

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis.

Vereecke L, Sze M, Mc Guire C, Rogiers B, Chu Y, Schmidt-Supprian M, Pasparakis M, Beyaert R, van Loo G.

J Exp Med. 2010 Jul 5;207(7):1513-23. doi: 10.1084/jem.20092474. Epub 2010 Jun 7.

PMID:
20530205
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-kappaB target genes.

Wolfrum S, Teupser D, Tan M, Chen KY, Breslow JL.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18601-6. Epub 2007 Nov 15.

PMID:
18006655
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes.

Shembade N, Ma A, Harhaj EW.

Science. 2010 Feb 26;327(5969):1135-9. doi: 10.1126/science.1182364.

PMID:
20185725
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Signaling and subcellular localization of the TNF receptor Edar.

Koppinen P, Pispa J, Laurikkala J, Thesleff I, Mikkola ML.

Exp Cell Res. 2001 Oct 1;269(2):180-92.

PMID:
11570810
[PubMed - indexed for MEDLINE]

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