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Results: 1 to 20 of 90

1.

Histone deacetylase inhibitors prime medulloblastoma cells for chemotherapy-induced apoptosis by enhancing p53-dependent Bax activation.

Häcker S, Karl S, Mader I, Cristofanon S, Schweitzer T, Krauss J, Rutkowski S, Debatin KM, Fulda S.

Oncogene. 2011 May 12;30(19):2275-81. doi: 10.1038/onc.2010.599. Epub 2011 Jan 17.

PMID:
21562496
[PubMed - indexed for MEDLINE]
2.

PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2 proteins and enhanced mitochondrial apoptosis.

Bender A, Opel D, Naumann I, Kappler R, Friedman L, von Schweinitz D, Debatin KM, Fulda S.

Oncogene. 2011 Jan 27;30(4):494-503. doi: 10.1038/onc.2010.429. Epub 2010 Sep 20.

PMID:
20856197
[PubMed - indexed for MEDLINE]
3.

Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8.

Häcker S, Dittrich A, Mohr A, Schweitzer T, Rutkowski S, Krauss J, Debatin KM, Fulda S.

Oncogene. 2009 Sep 3;28(35):3097-110. doi: 10.1038/onc.2009.161. Epub 2009 Jul 13.

PMID:
19597472
[PubMed - indexed for MEDLINE]
4.

Chemosensitization of rhabdomyosarcoma cells by the histone deacetylase inhibitor SAHA.

Heinicke U, Fulda S.

Cancer Lett. 2014 Aug 28;351(1):50-8. doi: 10.1016/j.canlet.2014.04.021. Epub 2014 May 6.

PMID:
24814395
[PubMed - indexed for MEDLINE]
5.

The histone deacetylase inhibitor trichostatin A induces cell cycle arrest and apoptosis in colorectal cancer cells via p53-dependent and -independent pathways.

Meng J, Zhang HH, Zhou CX, Li C, Zhang F, Mei QB.

Oncol Rep. 2012 Jul;28(1):384-8. doi: 10.3892/or.2012.1793. Epub 2012 Apr 30.

PMID:
22552631
[PubMed - indexed for MEDLINE]
6.

Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells.

Dong G, Luo J, Kumar V, Dong Z.

Am J Physiol Renal Physiol. 2010 Feb;298(2):F293-300. doi: 10.1152/ajprenal.00410.2009. Epub 2009 Nov 4.

PMID:
19889954
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway.

Hu H, Jiang C, Schuster T, Li GX, Daniel PT, Lü J.

Mol Cancer Ther. 2006 Jul;5(7):1873-82.

PMID:
16891474
[PubMed - indexed for MEDLINE]
Free Article
8.

Induction of apoptosis in renal tubular cells by histone deacetylase inhibitors, a family of anticancer agents.

Dong G, Wang L, Wang CY, Yang T, Kumar MV, Dong Z.

J Pharmacol Exp Ther. 2008 Jun;325(3):978-84. doi: 10.1124/jpet.108.137398. Epub 2008 Feb 29.

PMID:
18310471
[PubMed - indexed for MEDLINE]
Free Article
9.

Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models.

Sasaki Y, Negishi H, Idogawa M, Suzuki H, Mita H, Toyota M, Shinomura Y, Imai K, Tokino T.

Mol Cancer Ther. 2008 Apr;7(4):779-87. doi: 10.1158/1535-7163.MCT-07-0395.

PMID:
18413792
[PubMed - indexed for MEDLINE]
Free Article
10.
11.

Histone deacetylase inhibitors induce cell death and enhance the susceptibility to ionizing radiation, etoposide, and TRAIL in medulloblastoma cells.

Sonnemann J, Kumar KS, Heesch S, Müller C, Hartwig C, Maass M, Bader P, Beck JF.

Int J Oncol. 2006 Mar;28(3):755-66.

PMID:
16465382
[PubMed - indexed for MEDLINE]
12.
13.

KD5170, a novel mercaptoketone-based histone deacetylase inhibitor, exerts antimyeloma effects by DNA damage and mitochondrial signaling.

Feng R, Ma H, Hassig CA, Payne JE, Smith ND, Mapara MY, Hager JH, Lentzsch S.

Mol Cancer Ther. 2008 Jun;7(6):1494-505. doi: 10.1158/1535-7163.MCT-08-0183.

PMID:
18566220
[PubMed - indexed for MEDLINE]
Free Article
14.

Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.

Cheong JW, Chong SY, Kim JY, Eom JI, Jeung HK, Maeng HY, Lee ST, Min YH.

Clin Cancer Res. 2003 Oct 15;9(13):5018-27.

PMID:
14581377
[PubMed - indexed for MEDLINE]
Free Article
15.

Overexpression of histone deacetylase 1 confers resistance to sodium butyrate-mediated apoptosis in melanoma cells through a p53-mediated pathway.

Bandyopadhyay D, Mishra A, Medrano EE.

Cancer Res. 2004 Nov 1;64(21):7706-10.

PMID:
15520174
[PubMed - indexed for MEDLINE]
Free Article
16.

Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA).

Henderson C, Mizzau M, Paroni G, Maestro R, Schneider C, Brancolini C.

J Biol Chem. 2003 Apr 4;278(14):12579-89. Epub 2003 Jan 29.

PMID:
12556448
[PubMed - indexed for MEDLINE]
Free Article
17.

Andrographolide enhances 5-fluorouracil-induced apoptosis via caspase-8-dependent mitochondrial pathway involving p53 participation in hepatocellular carcinoma (SMMC-7721) cells.

Yang L, Wu D, Luo K, Wu S, Wu P.

Cancer Lett. 2009 Apr 18;276(2):180-8. doi: 10.1016/j.canlet.2008.11.015. Epub 2008 Dec 20.

PMID:
19097688
[PubMed - indexed for MEDLINE]
18.

Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.

Wang S, El-Deiry WS.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15095-100. Epub 2003 Nov 26.

PMID:
14645705
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors.

Fulda S, Friesen C, Los M, Scaffidi C, Mier W, Benedict M, Nuñez G, Krammer PH, Peter ME, Debatin KM.

Cancer Res. 1997 Nov 1;57(21):4956-64.

PMID:
9354463
[PubMed - indexed for MEDLINE]
Free Article
20.

Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors.

Subramanian C, Opipari AW Jr, Bian X, Castle VP, Kwok RP.

Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4842-7. Epub 2005 Mar 18.

PMID:
15778293
[PubMed - indexed for MEDLINE]
Free PMC Article
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