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Results: 1 to 20 of 102

1.

Targeting superficial or nodular Basal cell carcinoma with topically formulated small molecule inhibitor of smoothened.

Tang T, Tang JY, Li D, Reich M, Callahan CA, Fu L, Yauch RL, Wang F, Kotkow K, Chang KS, Shpall E, Wu A, Rubin LL, Marsters JC Jr, Epstein EH Jr, Caro I, de Sauvage FJ.

Clin Cancer Res. 2011 May 15;17(10):3378-87. doi: 10.1158/1078-0432.CCR-10-3370. Epub 2011 May 10.

PMID:
21558397
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor.

Skvara H, Kalthoff F, Meingassner JG, Wolff-Winiski B, Aschauer H, Kelleher JF, Wu X, Pan S, Mickel L, Schuster C, Stary G, Jalili A, David OJ, Emotte C, Antunes AM, Rose K, Decker J, Carlson I, Gardner H, Stuetz A, Bertolino AP, Stingl G, De Rie MA.

J Invest Dermatol. 2011 Aug;131(8):1735-44. doi: 10.1038/jid.2011.48. Epub 2011 Mar 24.

PMID:
21430703
[PubMed - indexed for MEDLINE]
Free Article
3.

Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions.

Williams JA, Guicherit OM, Zaharian BI, Xu Y, Chai L, Wichterle H, Kon C, Gatchalian C, Porter JA, Rubin LL, Wang FY.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4616-21. Epub 2003 Apr 4. Erratum in: Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8607.

PMID:
12679522
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.

Grachtchouk M, Pero J, Yang SH, Ermilov AN, Michael LE, Wang A, Wilbert D, Patel RM, Ferris J, Diener J, Allen M, Lim S, Syu LJ, Verhaegen M, Dlugosz AA.

J Clin Invest. 2011 May;121(5):1768-81. doi: 10.1172/JCI46307. Epub 2011 Apr 25.

PMID:
21519145
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Open study of the efficacy and mechanism of action of topical imiquimod in basal cell carcinoma.

Vidal D, Matías-Guiu X, Alomar A.

Clin Exp Dermatol. 2004 Sep;29(5):518-25.

PMID:
15347339
[PubMed - indexed for MEDLINE]
6.

Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity.

Villani RM, Adolphe C, Palmer J, Waters MJ, Wainwright BJ.

Cancer Prev Res (Phila). 2010 Oct;3(10):1222-34. doi: 10.1158/1940-6207.CAPR-10-0082. Epub 2010 Sep 21.

PMID:
20858761
[PubMed - indexed for MEDLINE]
7.

Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle.

Hutchin ME, Kariapper MS, Grachtchouk M, Wang A, Wei L, Cummings D, Liu J, Michael LE, Glick A, Dlugosz AA.

Genes Dev. 2005 Jan 15;19(2):214-23. Epub 2004 Dec 29.

PMID:
15625189
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Efficacy of photodynamic therapy with methyl aminolevulinate in the treatment of superficial and nodular basal cell carcinoma: an open-label trial.

Surrenti T, De Angelis L, Di Cesare A, Fargnoli MC, Peris K.

Eur J Dermatol. 2007 Sep-Oct;17(5):412-5. Epub 2007 Aug 2.

PMID:
17673385
[PubMed - indexed for MEDLINE]
9.

Successful treatment of multiple superficial basal cell carcinomas with topical imiquimod: case report and review of the literature.

Drehs MM, Cook-Bolden F, Tanzi EL, Weinberg JM.

Dermatol Surg. 2002 May;28(5):427-9. Review.

PMID:
12030878
[PubMed - indexed for MEDLINE]
10.

Targeting the hedgehog pathway to treat basal cell carcinoma.

Geeraert P, Williams JS, Brownell I.

J Drugs Dermatol. 2013 May;12(5):519-23. Review.

PMID:
23652945
[PubMed - indexed for MEDLINE]
11.

Hedgehog signaling pathway as a target for therapeutic intervention in basal cell carcinoma.

Williams JA.

Drug News Perspect. 2003 Dec;16(10):657-62. Review.

PMID:
14747845
[PubMed - indexed for MEDLINE]
12.

Imiquimod treatment of superficial and nodular basal cell carcinoma: 12-week open-label trial.

Peris K, Campione E, Micantonio T, Marulli GC, Fargnoli MC, Chimenti S.

Dermatol Surg. 2005 Mar;31(3):318-23.

PMID:
15841634
[PubMed - indexed for MEDLINE]
13.

Interaction of hedgehog and vitamin D signaling pathways in basal cell carcinomas.

Albert B, Hahn H.

Adv Exp Med Biol. 2014;810:329-41. Review.

PMID:
25207374
[PubMed - indexed for MEDLINE]
14.

Basal cell carcinoma and its development: insights from radiation-induced tumors in Ptch1-deficient mice.

Mancuso M, Pazzaglia S, Tanori M, Hahn H, Merola P, Rebessi S, Atkinson MJ, Di Majo V, Covelli V, Saran A.

Cancer Res. 2004 Feb 1;64(3):934-41.

PMID:
14871823
[PubMed - indexed for MEDLINE]
Free Article
15.

Topical treatment of basal cell carcinoma with tazarotene: a clinicopathological study on a large series of cases.

Bianchi L, Orlandi A, Campione E, Angeloni C, Costanzo A, Spagnoli LG, Chimenti S.

Br J Dermatol. 2004 Jul;151(1):148-56.

PMID:
15270884
[PubMed - indexed for MEDLINE]
16.

Topical imiquimod treatment for nodular basal cell carcinomas: an open-label series.

Huber A, Huber JD, Skinner RB Jr, Kuwahara RT, Haque R, Amonette RA.

Dermatol Surg. 2004 Mar;30(3):429-30.

PMID:
15008876
[PubMed - indexed for MEDLINE]
17.

Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis.

Athar M, Li C, Tang X, Chi S, Zhang X, Kim AL, Tyring SK, Kopelovich L, Hebert J, Epstein EH Jr, Bickers DR, Xie J.

Cancer Res. 2004 Oct 15;64(20):7545-52.

PMID:
15492281
[PubMed - indexed for MEDLINE]
Free Article
18.

Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib.

Chang AL, Solomon JA, Hainsworth JD, Goldberg L, McKenna E, Day BM, Chen DM, Weiss GJ.

J Am Acad Dermatol. 2014 Jan;70(1):60-9. doi: 10.1016/j.jaad.2013.09.012. Epub 2013 Nov 1.

PMID:
24189279
[PubMed - indexed for MEDLINE]
Free Article
19.

Clinical experience with Hedgehog pathway inhibitors.

Low JA, de Sauvage FJ.

J Clin Oncol. 2010 Dec 20;28(36):5321-6. doi: 10.1200/JCO.2010.27.9943. Epub 2010 Nov 1.

PMID:
21041712
[PubMed - indexed for MEDLINE]
Free Article
20.

Vismodegib in basal cell carcinoma.

Amaria RN, Bowles DW, Lewis KD, Jimeno A.

Drugs Today (Barc). 2012 Jul;48(7):459-67. doi: 10.1358/dot.2012.48.7.1808490. Review.

PMID:
22844657
[PubMed - indexed for MEDLINE]

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