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Results: 1 to 20 of 113

1.

Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development.

Le LQ, Liu C, Shipman T, Chen Z, Suter U, Parada LF.

Cancer Res. 2011 Jul 1;71(13):4686-95. doi: 10.1158/0008-5472.CAN-10-4577. Epub 2011 May 6.

PMID:
21551250
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation.

Mayes DA, Rizvi TA, Cancelas JA, Kolasinski NT, Ciraolo GM, Stemmer-Rachamimov AO, Ratner N.

Cancer Res. 2011 Jul 1;71(13):4675-85. doi: 10.1158/0008-5472.CAN-10-4558. Epub 2011 May 6.

PMID:
21551249
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Neurofibromas in NF1: Schwann cell origin and role of tumor environment.

Zhu Y, Ghosh P, Charnay P, Burns DK, Parada LF.

Science. 2002 May 3;296(5569):920-2.

PMID:
11988578
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells.

Wu J, Williams JP, Rizvi TA, Kordich JJ, Witte D, Meijer D, Stemmer-Rachamimov AO, Cancelas JA, Ratner N.

Cancer Cell. 2008 Feb;13(2):105-16. doi: 10.1016/j.ccr.2007.12.027.

PMID:
18242511
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.

Brossier NM, Carroll SL.

Brain Res Bull. 2012 May 1;88(1):58-71. doi: 10.1016/j.brainresbull.2011.08.005. Epub 2011 Aug 10. Review.

PMID:
21855613
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells.

Staser K, Yang FC, Clapp DW.

Curr Opin Hematol. 2010 Jul;17(4):287-93. doi: 10.1097/MOH.0b013e328339511b. Review.

PMID:
20571392
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow.

Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y, Zhang S, Yang Y, Vakili ST, Yu M, Burns D, Robertson K, Hutchins G, Parada LF, Clapp DW.

Cell. 2008 Oct 31;135(3):437-48. doi: 10.1016/j.cell.2008.08.041.

PMID:
18984156
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Neurofibromatosis Type 1 and tumorigenesis: molecular mechanisms and therapeutic implications.

Gottfried ON, Viskochil DH, Couldwell WT.

Neurosurg Focus. 2010 Jan;28(1):E8. doi: 10.3171/2009.11.FOCUS09221.

PMID:
20043723
[PubMed - indexed for MEDLINE]
9.

How does the Schwann cell lineage form tumors in NF1?

Carroll SL, Ratner N.

Glia. 2008 Nov 1;56(14):1590-605. doi: 10.1002/glia.20776. Review.

PMID:
18803326
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells.

Mashour GA, Ratner N, Khan GA, Wang HL, Martuza RL, Kurtz A.

Oncogene. 2001 Jan 4;20(1):97-105.

PMID:
11244508
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells.

Yang FC, Ingram DA, Chen S, Hingtgen CM, Ratner N, Monk KR, Clegg T, White H, Mead L, Wenning MJ, Williams DA, Kapur R, Atkinson SJ, Clapp DW.

J Clin Invest. 2003 Dec;112(12):1851-61.

PMID:
14679180
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Schwann cells harbor the somatic NF1 mutation in neurofibromas: evidence of two different Schwann cell subpopulations.

Serra E, Rosenbaum T, Winner U, Aledo R, Ars E, Estivill X, Lenard HG, Lázaro C.

Hum Mol Genet. 2000 Dec 12;9(20):3055-64.

PMID:
11115850
[PubMed - indexed for MEDLINE]
Free Article
14.

Clonal origin of tumor cells in a plexiform neurofibroma with LOH in NF1 intron 38 and in dermal neurofibromas without LOH of the NF1 gene.

Däschner K, Assum G, Eisenbarth I, Krone W, Hoffmeyer S, Wortmann S, Heymer B, Kehrer-Sawatzki H.

Biochem Biophys Res Commun. 1997 May 19;234(2):346-50.

PMID:
9177273
[PubMed - indexed for MEDLINE]
15.

Induction of abnormal proliferation by nonmyelinating schwann cells triggers neurofibroma formation.

Zheng H, Chang L, Patel N, Yang J, Lowe L, Burns DK, Zhu Y.

Cancer Cell. 2008 Feb;13(2):117-28. doi: 10.1016/j.ccr.2008.01.002.

PMID:
18242512
[PubMed - indexed for MEDLINE]
Free Article
16.

Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development.

Shin J, Padmanabhan A, de Groh ED, Lee JS, Haidar S, Dahlberg S, Guo F, He S, Wolman MA, Granato M, Lawson ND, Wolfe SA, Kim SH, Solnica-Krezel L, Kanki JP, Ligon KL, Epstein JA, Look AT.

Dis Model Mech. 2012 Nov;5(6):881-94. doi: 10.1242/dmm.009779. Epub 2012 Jul 5.

PMID:
22773753
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Molecular profiling of malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1, based on large-scale real-time RT-PCR.

Lévy P, Vidaud D, Leroy K, Laurendeau I, Wechsler J, Bolasco G, Parfait B, Wolkenstein P, Vidaud M, Bièche I.

Mol Cancer. 2004 Jul 15;3:20.

PMID:
15255999
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis.

Ling BC, Wu J, Miller SJ, Monk KR, Shamekh R, Rizvi TA, Decourten-Myers G, Vogel KS, DeClue JE, Ratner N.

Cancer Cell. 2005 Jan;7(1):65-75.

PMID:
15652750
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Analysis of somatic NF1 promoter methylation in plexiform neurofibromas and Schwann cells.

Fishbein L, Eady B, Sanek N, Muir D, Wallace MR.

Cancer Genet Cytogenet. 2005 Mar;157(2):181-6.

PMID:
15721644
[PubMed - indexed for MEDLINE]
20.

Injury signals cooperate with Nf1 loss to relieve the tumor-suppressive environment of adult peripheral nerve.

Ribeiro S, Napoli I, White IJ, Parrinello S, Flanagan AM, Suter U, Parada LF, Lloyd AC.

Cell Rep. 2013 Oct 17;5(1):126-36. doi: 10.1016/j.celrep.2013.08.033. Epub 2013 Sep 26.

PMID:
24075988
[PubMed - indexed for MEDLINE]
Free Article

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