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Items: 1 to 20 of 106

1.

Spontaneous membrane-translocating peptides by orthogonal high-throughput screening.

Marks JR, Placone J, Hristova K, Wimley WC.

J Am Chem Soc. 2011 Jun 15;133(23):8995-9004. doi: 10.1021/ja2017416. Epub 2011 May 19.

2.

Direct cytosolic delivery of polar cargo to cells by spontaneous membrane-translocating peptides.

He J, Kauffman WB, Fuselier T, Naveen SK, Voss TG, Hristova K, Wimley WC.

J Biol Chem. 2013 Oct 11;288(41):29974-86. doi: 10.1074/jbc.M113.488312. Epub 2013 Aug 27.

3.

A membrane-translocating peptide penetrates into bilayers without significant bilayer perturbations.

Cruz J, Mihailescu M, Wiedman G, Herman K, Searson PC, Wimley WC, Hristova K.

Biophys J. 2013 Jun 4;104(11):2419-28. doi: 10.1016/j.bpj.2013.04.043.

4.

Tat(48-60) peptide amino acid sequence is not unique in its cell penetrating properties and cell-surface glycosaminoglycans inhibit its cellular uptake.

Subrizi A, Tuominen E, Bunker A, Róg T, Antopolsky M, Urtti A.

J Control Release. 2012 Mar 10;158(2):277-85. doi: 10.1016/j.jconrel.2011.11.007. Epub 2011 Nov 12.

PMID:
22100438
5.

Spontaneous membrane-translocating peptides: influence of peptide self-aggregation and cargo polarity.

Macchi S, Signore G, Boccardi C, Di Rienzo C, Beltram F, Cardarelli F.

Sci Rep. 2015 Nov 16;5:16914. doi: 10.1038/srep16914.

6.

Interactions of membrane active peptides with planar supported bilayers: an impedance spectroscopy study.

Lin J, Motylinski J, Krauson AJ, Wimley WC, Searson PC, Hristova K.

Langmuir. 2012 Apr 10;28(14):6088-96. doi: 10.1021/la300274n. Epub 2012 Mar 28.

PMID:
22416892
7.

Non-metabolic membrane tubulation and permeability induced by bioactive peptides.

Lamazière A, Burlina F, Wolf C, Chassaing G, Trugnan G, Ayala-Sanmartin J.

PLoS One. 2007 Feb 14;2(2):e201.

8.

Membrane binding and translocation of cell-penetrating peptides.

Thorén PE, Persson D, Esbjörner EK, Goksör M, Lincoln P, Nordén B.

Biochemistry. 2004 Mar 30;43(12):3471-89.

PMID:
15035618
9.

Synthetic molecular evolution of pore-forming peptides by iterative combinatorial library screening.

Krauson AJ, He J, Wimley AW, Hoffmann AR, Wimley WC.

ACS Chem Biol. 2013 Apr 19;8(4):823-31. doi: 10.1021/cb300598k. Epub 2013 Feb 20.

11.

Novel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules.

De Coupade C, Fittipaldi A, Chagnas V, Michel M, Carlier S, Tasciotti E, Darmon A, Ravel D, Kearsey J, Giacca M, Cailler F.

Biochem J. 2005 Sep 1;390(Pt 2):407-18.

12.

Biomolecular engineering by combinatorial design and high-throughput screening: small, soluble peptides that permeabilize membranes.

Rathinakumar R, Wimley WC.

J Am Chem Soc. 2008 Jul 30;130(30):9849-58. doi: 10.1021/ja8017863. Epub 2008 Jul 9.

13.

GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery.

Li W, Nicol F, Szoka FC Jr.

Adv Drug Deliv Rev. 2004 Apr 23;56(7):967-85. Review.

PMID:
15066755
14.

Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes.

Herce HD, Garcia AE.

Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20805-10. Epub 2007 Dec 18.

15.

On the mechanisms of the internalization of S4(13)-PV cell-penetrating peptide.

Mano M, Teodósio C, Paiva A, Simões S, Pedroso de Lima MC.

Biochem J. 2005 Sep 1;390(Pt 2):603-12.

16.
17.

Cell membranes open "doors" for cationic nanoparticles/biomolecules: insights into uptake kinetics.

Lin J, Alexander-Katz A.

ACS Nano. 2013 Dec 23;7(12):10799-808. doi: 10.1021/nn4040553. Epub 2013 Nov 26.

PMID:
24251827
18.

Membrane interactions of two arginine-rich peptides with different cell internalization capacities.

Walrant A, Vogel A, Correia I, Lequin O, Olausson BE, Desbat B, Sagan S, Alves ID.

Biochim Biophys Acta. 2012 Jul;1818(7):1755-63.

19.

Designing transmembrane alpha-helices that insert spontaneously.

Wimley WC, White SH.

Biochemistry. 2000 Apr 18;39(15):4432-42.

PMID:
10757993
20.

Nucleic acid delivery by cell penetrating peptides derived from dengue virus capsid protein: design and mechanism of action.

Freire JM, Veiga AS, Rego de Figueiredo I, de la Torre BG, Santos NC, Andreu D, Da Poian AT, Castanho MA.

FEBS J. 2014 Jan;281(1):191-215. doi: 10.1111/febs.12587. Epub 2013 Nov 28.

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