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Results: 1 to 20 of 222

1.

Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cells.

Taylor MA, Amin JD, Kirschmann DA, Schiemann WP.

Neoplasia. 2011 May;13(5):406-18.

PMID:
21532881
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.

Wendt MK, Smith JA, Schiemann WP.

J Biol Chem. 2009 Dec 4;284(49):34145-56. doi: 10.1074/jbc.M109.023614. Epub 2009 Oct 12.

PMID:
19822523
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.
5.

The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells.

Taylor MA, Parvani JG, Schiemann WP.

J Mammary Gland Biol Neoplasia. 2010 Jun;15(2):169-90. doi: 10.1007/s10911-010-9181-1. Epub 2010 May 15. Review.

PMID:
20467795
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The Cain and Abl of epithelial-mesenchymal transition and transforming growth factor-β in mammary epithelial cells.

Allington TM, Schiemann WP.

Cells Tissues Organs. 2011;193(1-2):98-113. doi: 10.1159/000320163. Epub 2010 Nov 3. Review.

PMID:
21051857
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-beta through a PGE2-dependent mechanisms.

Neil JR, Johnson KM, Nemenoff RA, Schiemann WP.

Carcinogenesis. 2008 Nov;29(11):2227-35. doi: 10.1093/carcin/bgn202. Epub 2008 Aug 25.

PMID:
18725385
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF-beta in mammary epithelial cells via a MMP-dependent mechanism.

Lee YH, Albig AR, Regner M, Schiemann BJ, Schiemann WP.

Carcinogenesis. 2008 Dec;29(12):2243-51. doi: 10.1093/carcin/bgn199. Epub 2008 Aug 19.

PMID:
18713838
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Noncanonical TGF-β signaling during mammary tumorigenesis.

Parvani JG, Taylor MA, Schiemann WP.

J Mammary Gland Biol Neoplasia. 2011 Jun;16(2):127-46. doi: 10.1007/s10911-011-9207-3. Epub 2011 Mar 31. Review.

PMID:
21448580
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Regulation of elastin promoter by lysyl oxidase and growth factors: cross control of lysyl oxidase on TGF-beta1 effects.

Oleggini R, Gastaldo N, Di Donato A.

Matrix Biol. 2007 Jul;26(6):494-505. Epub 2007 Feb 27.

PMID:
17395448
[PubMed - indexed for MEDLINE]
11.

PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-beta signaling during mammary tumorigenesis.

Tian M, Schiemann WP.

FASEB J. 2010 Apr;24(4):1105-16. doi: 10.1096/fj.09-141341. Epub 2009 Nov 6.

PMID:
19897661
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Transforming growth factor-β 1 enhances the invasiveness of breast cancer cells by inducing a Smad2-dependent epithelial-to-mesenchymal transition.

Lv ZD, Kong B, Li JG, Qu HL, Wang XG, Cao WH, Liu XY, Wang Y, Yang ZC, Xu HM, Wang HB.

Oncol Rep. 2013 Jan;29(1):219-25. doi: 10.3892/or.2012.2111. Epub 2012 Oct 30.

PMID:
23129177
[PubMed - indexed for MEDLINE]
13.

Role of Smad2/3 and p38 MAP kinase in TGF-β1-induced epithelial-mesenchymal transition of pulmonary epithelial cells.

Kolosova I, Nethery D, Kern JA.

J Cell Physiol. 2011 May;226(5):1248-54. doi: 10.1002/jcp.22448.

PMID:
20945383
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β.

Parvani JG, Galliher-Beckley AJ, Schiemann BJ, Schiemann WP.

Mol Biol Cell. 2013 Nov;24(21):3449-59. doi: 10.1091/mbc.E12-10-0776. Epub 2013 Sep 4.

PMID:
24006485
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK.

Lofgren KA, Ostrander JH, Housa D, Hubbard GK, Locatelli A, Bliss RL, Schwertfeger KL, Lange CA.

Breast Cancer Res. 2011 Sep 17;13(5):R89. doi: 10.1186/bcr2946.

PMID:
21923922
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Grb2 binding to Tyr284 in TbetaR-II is essential for mammary tumor growth and metastasis stimulated by TGF-beta.

Galliher-Beckley AJ, Schiemann WP.

Carcinogenesis. 2008 Feb;29(2):244-51. doi: 10.1093/carcin/bgm245. Epub 2008 Jan 3.

PMID:
18174260
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Transforming growth factor-{beta}1 induces Smad3-dependent {beta}1 integrin gene expression in epithelial-to-mesenchymal transition during chronic tubulointerstitial fibrosis.

Yeh YC, Wei WC, Wang YK, Lin SC, Sung JM, Tang MJ.

Am J Pathol. 2010 Oct;177(4):1743-54. doi: 10.2353/ajpath.2010.091183. Epub 2010 Aug 13.

PMID:
20709799
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway.

Chen LC, Tu SH, Huang CS, Chen CS, Ho CT, Lin HW, Lee CH, Chang HW, Chang CH, Wu CH, Lee WS, Ho YS.

Breast Cancer Res Treat. 2012 Aug;134(3):989-1004. doi: 10.1007/s10549-012-1986-8. Epub 2012 Mar 21.

PMID:
22434522
[PubMed - indexed for MEDLINE]
19.

Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling.

Voloshenyuk TG, Landesman ES, Khoutorova E, Hart AD, Gardner JD.

Cytokine. 2011 Jul;55(1):90-7. doi: 10.1016/j.cyto.2011.03.024. Epub 2011 Apr 17.

PMID:
21498085
[PubMed - indexed for MEDLINE]
20.

HER-2 overexpression differentially alters transforming growth factor-beta responses in luminal versus mesenchymal human breast cancer cells.

Wilson CA, Cajulis EE, Green JL, Olsen TM, Chung YA, Damore MA, Dering J, Calzone FJ, Slamon DJ.

Breast Cancer Res. 2005;7(6):R1058-79. Epub 2005 Nov 8.

PMID:
16457687
[PubMed - indexed for MEDLINE]
Free PMC Article

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