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Items: 1 to 20 of 107


Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling.

Tan CL, Kwok JC, Patani R, Ffrench-Constant C, Chandran S, Fawcett JW.

J Neurosci. 2011 Apr 27;31(17):6289-95. doi: 10.1523/JNEUROSCI.0008-11.2011.


Kindlin-1 enhances axon growth on inhibitory chondroitin sulfate proteoglycans and promotes sensory axon regeneration.

Tan CL, Andrews MR, Kwok JC, Heintz TG, Gumy LF, Fässler R, Fawcett JW.

J Neurosci. 2012 May 23;32(21):7325-35. doi: 10.1523/JNEUROSCI.5472-11.2012.


Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ.

Pendleton JC, Shamblott MJ, Gary DS, Belegu V, Hurtado A, Malone ML, McDonald JW.

Exp Neurol. 2013 Sep;247:113-21. doi: 10.1016/j.expneurol.2013.04.003. Epub 2013 Apr 12.


Embryonic neurons adapt to the inhibitory proteoglycan aggrecan by increasing integrin expression.

Condic ML, Snow DM, Letourneau PC.

J Neurosci. 1999 Nov 15;19(22):10036-43.


Neurotrophins support regenerative axon assembly over CSPGs by an ECM-integrin-independent mechanism.

Zhou FQ, Walzer M, Wu YH, Zhou J, Dedhar S, Snider WD.

J Cell Sci. 2006 Jul 1;119(Pt 13):2787-96. Epub 2006 Jun 13.


Activation of PI3K and R-Ras signaling promotes the extension of sensory axons on inhibitory chondroitin sulfate proteoglycans.

Silver L, Michael JV, Goldfinger LE, Gallo G.

Dev Neurobiol. 2014 Sep;74(9):918-33. doi: 10.1002/dneu.22174. Epub 2014 Mar 27.


Benefit of chondroitinase ABC on sensory axon regeneration in a laceration model of spinal cord injury in the rat.

Shields LB, Zhang YP, Burke DA, Gray R, Shields CB.

Surg Neurol. 2008 Jun;69(6):568-77; discussion 577. doi: 10.1016/j.surneu.2008.02.009.


ARF6 directs axon transport and traffic of integrins and regulates axon growth in adult DRG neurons.

Eva R, Crisp S, Marland JR, Norman JC, Kanamarlapudi V, ffrench-Constant C, Fawcett JW.

J Neurosci. 2012 Jul 25;32(30):10352-64.


Adaptation of sensory neurons to hyalectin and decorin proteoglycans.

Lemons ML, Barua S, Abanto ML, Halfter W, Condic ML.

J Neurosci. 2005 May 18;25(20):4964-73.


The unusual response of serotonergic neurons after CNS Injury: lack of axonal dieback and enhanced sprouting within the inhibitory environment of the glial scar.

Hawthorne AL, Hu H, Kundu B, Steinmetz MP, Wylie CJ, Deneris ES, Silver J.

J Neurosci. 2011 Apr 13;31(15):5605-16. doi: 10.1523/JNEUROSCI.6663-10.2011.


Limited growth of severed CNS axons after treatment of adult rat brain with hyaluronidase.

Moon LD, Asher RA, Fawcett JW.

J Neurosci Res. 2003 Jan 1;71(1):23-37.


Scar-mediated inhibition and CSPG receptors in the CNS.

Sharma K, Selzer ME, Li S.

Exp Neurol. 2012 Oct;237(2):370-8. doi: 10.1016/j.expneurol.2012.07.009. Epub 2012 Jul 24. Review.


Role of chondroitin sulfate proteoglycans in axonal conduction in Mammalian spinal cord.

Hunanyan AS, García-Alías G, Alessi V, Levine JM, Fawcett JW, Mendell LM, Arvanian VL.

J Neurosci. 2010 Jun 9;30(23):7761-9. doi: 10.1523/JNEUROSCI.4659-09.2010.


Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3.

Massey JM, Amps J, Viapiano MS, Matthews RT, Wagoner MR, Whitaker CM, Alilain W, Yonkof AL, Khalyfa A, Cooper NG, Silver J, Onifer SM.

Exp Neurol. 2008 Feb;209(2):426-45. Epub 2007 Apr 12.


PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration.

Shen Y, Tenney AP, Busch SA, Horn KP, Cuascut FX, Liu K, He Z, Silver J, Flanagan JG.

Science. 2009 Oct 23;326(5952):592-6. doi: 10.1126/science.1178310. Epub 2009 Oct 15.


Atypical protein kinase C and Par3 are required for proteoglycan-induced axon growth inhibition.

Lee SI, Zhang W, Ravi M, Weschenfelder M, Bastmeyer M, Levine JM.

J Neurosci. 2013 Feb 6;33(6):2541-54. doi: 10.1523/JNEUROSCI.3154-12.2013.


Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors.

Fisher D, Xing B, Dill J, Li H, Hoang HH, Zhao Z, Yang XL, Bachoo R, Cannon S, Longo FM, Sheng M, Silver J, Li S.

J Neurosci. 2011 Oct 5;31(40):14051-66. doi: 10.1523/JNEUROSCI.1737-11.2011.


Decorin promotes robust axon growth on inhibitory CSPGs and myelin via a direct effect on neurons.

Minor K, Tang X, Kahrilas G, Archibald SJ, Davies JE, Davies SJ.

Neurobiol Dis. 2008 Oct;32(1):88-95. doi: 10.1016/j.nbd.2008.06.009. Epub 2008 Jun 26.


Axon behaviour at Schwann cell - astrocyte boundaries: manipulation of axon signalling pathways and the neural adhesion molecule L1 can enable axons to cross.

Adcock KH, Brown DJ, Shearer MC, Shewan D, Schachner M, Smith GM, Geller HM, Fawcett JW.

Eur J Neurosci. 2004 Sep;20(6):1425-35.

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