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Items: 1 to 20 of 134

1.

Premature aging with impaired oxidative stress defense in mice lacking TR4.

Lee YF, Liu S, Liu NC, Wang RS, Chen LM, Lin WJ, Ting HJ, Ho HC, Li G, Puzas EJ, Wu Q, Chang C.

Am J Physiol Endocrinol Metab. 2011 Jul;301(1):E91-8. doi: 10.1152/ajpendo.00701.2010. Epub 2011 Apr 26.

2.

Oxidative DNA damage causes premature senescence in mouse embryonic fibroblasts deficient for Krüppel-like factor 4.

Liu C, La Rosa S, Hagos EG.

Mol Carcinog. 2015 Sep;54(9):889-99. doi: 10.1002/mc.22161. Epub 2014 Apr 30.

PMID:
24788960
3.

Oxidative stress stimulates testicular orphan receptor 4 through forkhead transcription factor forkhead box O3a.

Li G, Lee YF, Liu S, Cai Y, Xie S, Liu NC, Bao BY, Chen Z, Chang C.

Endocrinology. 2008 Jul;149(7):3490-9. doi: 10.1210/en.2008-0121. Epub 2008 Apr 3.

4.
5.

Growth retardation and abnormal maternal behavior in mice lacking testicular orphan nuclear receptor 4.

Collins LL, Lee YF, Heinlein CA, Liu NC, Chen YT, Shyr CR, Meshul CK, Uno H, Platt KA, Chang C.

Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15058-63. Epub 2004 Oct 11.

6.

Genomic instability in laminopathy-based premature aging.

Liu B, Wang J, Chan KM, Tjia WM, Deng W, Guan X, Huang JD, Li KM, Chau PY, Chen DJ, Pei D, Pendas AM, Cadiñanos J, López-Otín C, Tse HF, Hutchison C, Chen J, Cao Y, Cheah KS, Tryggvason K, Zhou Z.

Nat Med. 2005 Jul;11(7):780-5. Epub 2005 Jun 26.

PMID:
15980864
7.

Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice.

Shalini S, Dorstyn L, Wilson C, Puccini J, Ho L, Kumar S.

Cell Death Differ. 2012 Aug;19(8):1370-80. doi: 10.1038/cdd.2012.13. Epub 2012 Feb 17.

8.

DNA repair, genome stability, and aging.

Lombard DB, Chua KF, Mostoslavsky R, Franco S, Gostissa M, Alt FW.

Cell. 2005 Feb 25;120(4):497-512. Review.

9.

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production.

Trifunovic A, Hansson A, Wredenberg A, Rovio AT, Dufour E, Khvorostov I, Spelbrink JN, Wibom R, Jacobs HT, Larsson NG.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):17993-8. Epub 2005 Dec 6.

10.

Roles of testicular orphan nuclear receptors 2 and 4 in early embryonic development and embryonic stem cells.

Shyr CR, Kang HY, Tsai MY, Liu NC, Ku PY, Huang KE, Chang C.

Endocrinology. 2009 May;150(5):2454-62. doi: 10.1210/en.2008-1165. Epub 2009 Jan 8.

PMID:
19131575
11.

PTEN deletion leads to deregulation of antioxidants and increased oxidative damage in mouse embryonic fibroblasts.

Huo YY, Li G, Duan RF, Gou Q, Fu CL, Hu YC, Song BQ, Yang ZH, Wu DC, Zhou PK.

Free Radic Biol Med. 2008 Apr 15;44(8):1578-91. doi: 10.1016/j.freeradbiomed.2008.01.013. Epub 2008 Jan 26.

PMID:
18275859
12.

High oxidative damage levels in the longest-living rodent, the naked mole-rat.

Andziak B, O'Connor TP, Qi W, DeWaal EM, Pierce A, Chaudhuri AR, Van Remmen H, Buffenstein R.

Aging Cell. 2006 Dec;5(6):463-71. Epub 2006 Oct 27.

13.
14.

The roles of testicular orphan nuclear receptor 4 (TR4) in cerebellar development.

Chen YT, Collins LL, Chang SS, Chang C.

Cerebellum. 2008;7(1):9-17. doi: 10.1007/s12311-008-0006-3.

PMID:
18418664
15.

Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1.

Kondratov RV, Vykhovanets O, Kondratova AA, Antoch MP.

Aging (Albany NY). 2009 Dec 30;1(12):979-87.

16.

DDB2, an essential mediator of premature senescence.

Roy N, Stoyanova T, Dominguez-Brauer C, Park HJ, Bagchi S, Raychaudhuri P.

Mol Cell Biol. 2010 Jun;30(11):2681-92. doi: 10.1128/MCB.01480-09. Epub 2010 Mar 29.

17.

Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice.

Krishnan V, Chow MZ, Wang Z, Zhang L, Liu B, Liu X, Zhou Z.

Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12325-30. doi: 10.1073/pnas.1102789108. Epub 2011 Jul 11.

18.

Metformin inhibits nuclear receptor TR4-mediated hepatic stearoyl-CoA desaturase 1 gene expression with altered insulin sensitivity.

Kim E, Liu NC, Yu IC, Lin HY, Lee YF, Sparks JD, Chen LM, Chang C.

Diabetes. 2011 May;60(5):1493-503. doi: 10.2337/db10-0393. Epub 2011 Apr 8.

19.

Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence.

Zhan H, Suzuki T, Aizawa K, Miyagawa K, Nagai R.

J Biol Chem. 2010 Sep 17;285(38):29662-70. doi: 10.1074/jbc.M110.125138. Epub 2010 Jul 16.

20.
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