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Results: 1 to 20 of 103

1.

CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates.

Thompson P, Cardona K, Russell M, Badell IR, Shaffer V, Korbutt G, Rayat GR, Cano J, Song M, Jiang W, Strobert E, Rajotte R, Pearson T, Kirk AD, Larsen CP.

Am J Transplant. 2011 May;11(5):947-57. doi: 10.1111/j.1600-6143.2011.03509.x.

PMID:
21521467
[PubMed - indexed for MEDLINE]
Free Article
2.

Alternative immunomodulatory strategies for xenotransplantation: CD40/154 pathway-sparing regimens promote xenograft survival.

Thompson P, Badell IR, Lowe M, Turner A, Cano J, Avila J, Azimzadeh A, Cheng X, Pierson RN 3rd, Johnson B, Robertson J, Song M, Leopardi F, Strobert E, Korbutt G, Rayat G, Rajotte R, Larsen CP, Kirk AD.

Am J Transplant. 2012 Jul;12(7):1765-75. doi: 10.1111/j.1600-6143.2012.04031.x. Epub 2012 Mar 28.

PMID:
22458586
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Combination of anti-CD4 with anti-LFA-1 and anti-CD154 monoclonal antibodies promotes long-term survival and function of neonatal porcine islet xenografts in spontaneously diabetic NOD mice.

Arefanian H, Tredget EB, Rajotte RV, Korbutt GS, Gill RG, Rayat GR.

Cell Transplant. 2007;16(8):787-98.

PMID:
18087999
[PubMed - indexed for MEDLINE]
4.

Engraftment of adult porcine islet xenografts in diabetic nonhuman primates through targeting of costimulation pathways.

Cardona K, Milas Z, Strobert E, Cano J, Jiang W, Safley SA, Gangappa S, Hering BJ, Weber CJ, Pearson TC, Larsen CP.

Am J Transplant. 2007 Oct;7(10):2260-8.

PMID:
17845561
[PubMed - indexed for MEDLINE]
Free Article
5.

CTLA4Ig prevents alloantibody formation following nonhuman primate islet transplantation using the CD40-specific antibody 3A8.

Badell IR, Russell MC, Cardona K, Shaffer VO, Turner AP, Avila JG, Cano JA, Leopardi FV, Song M, Strobert EA, Ford ML, Pearson TC, Kirk AD, Larsen CP.

Am J Transplant. 2012 Jul;12(7):1918-23. doi: 10.1111/j.1600-6143.2012.04029.x. Epub 2012 Mar 28.

PMID:
22458552
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A novel monoclonal antibody to CD40 prolongs islet allograft survival.

Lowe M, Badell IR, Thompson P, Martin B, Leopardi F, Strobert E, Price AA, Abdulkerim HS, Wang R, Iwakoshi NN, Adams AB, Kirk AD, Larsen CP, Reimann KA.

Am J Transplant. 2012 Aug;12(8):2079-87. doi: 10.1111/j.1600-6143.2012.04054.x. Epub 2012 May 8.

PMID:
22845909
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Nondepleting anti-CD40-based therapy prolongs allograft survival in nonhuman primates.

Badell IR, Thompson PW, Turner AP, Russell MC, Avila JG, Cano JA, Robertson JM, Leopardi FV, Strobert EA, Iwakoshi NN, Reimann KA, Ford ML, Kirk AD, Larsen CP.

Am J Transplant. 2012 Jan;12(1):126-35. doi: 10.1111/j.1600-6143.2011.03736.x. Epub 2011 Sep 15.

PMID:
21920020
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Co-stimulatory molecules in islet xenotransplantation: CTLA4Ig treatment in CD40 ligand-deficient mice.

Benda B, Ljunggren HG, Peach R, Sandberg JO, Korsgren O.

Cell Transplant. 2002;11(7):715-20.

PMID:
12518898
[PubMed - indexed for MEDLINE]
9.

Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival.

Adams AB, Shirasugi N, Jones TR, Durham MM, Strobert EA, Cowan S, Rees P, Hendrix R, Price K, Kenyon NS, Hagerty D, Townsend R, Hollenbaugh D, Pearson TC, Larsen CP.

J Immunol. 2005 Jan 1;174(1):542-50.

PMID:
15611281
[PubMed - indexed for MEDLINE]
Free Article
10.

The efficacy of CD40 ligand blockade in discordant pig-to-rat islet xenotransplantation is correlated with an immunosuppressive effect of immunoglobulin.

Wennberg L, Goto M, Maeda A, Song Z, Benjamin C, Groth CG, Korsgren O.

Transplantation. 2005 Jan 27;79(2):157-64.

PMID:
15665763
[PubMed - indexed for MEDLINE]
11.

Inhibition of cellular immune responses to encapsulated porcine islet xenografts by simultaneous blockade of two different costimulatory pathways.

Safley SA, Kapp LM, Tucker-Burden C, Hering B, Kapp JA, Weber CJ.

Transplantation. 2005 Feb 27;79(4):409-18.

PMID:
15729166
[PubMed - indexed for MEDLINE]
12.

Protection of porcine islet xenografts in mice using sertoli cells and monoclonal antibodies.

Ramji QA, Bayrack K, Arefanian H, Marcet-Palacios M, Bleackley RC, Rajotte RV, Rayat GR.

Transplantation. 2011 Dec 27;92(12):1309-15. doi: 10.1097/TP.0b013e3182384ab0.

PMID:
22037619
[PubMed - indexed for MEDLINE]
13.

Adult porcine islet transplantation in baboons treated with conventional immunosuppression or a non-myeloablative regimen and CD154 blockade.

Bühler L, Deng S, O'Neil J, Kitamura H, Koulmanda M, Baldi A, Rahier J, Alwayn IP, Appel JZ, Awwad M, Sachs DH, Weir G, Squifflet JP, Cooper DK, Morel P.

Xenotransplantation. 2002 Jan;9(1):3-13.

PMID:
12005102
[PubMed - indexed for MEDLINE]
14.

Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody.

Appel MC, Banuelos SJ, Greiner DL, Shultz LD, Mordes JP, Rossini AA.

Transplantation. 2004 May 15;77(9):1341-9.

PMID:
15167588
[PubMed - indexed for MEDLINE]
15.

Anti-CD154 mAb treatment but not recipient CD154 deficiency leads to long-term survival of xenogeneic islet grafts.

Mai G, Bucher P, Morel P, Mei J, Bosco D, Andres A, Mathe Z, Wekerle T, Berney T, Bühler LH.

Am J Transplant. 2005 May;5(5):1021-31.

PMID:
15816882
[PubMed - indexed for MEDLINE]
Free Article
16.

Belatacept and sirolimus prolong nonhuman primate islet allograft survival: adverse consequences of concomitant alefacept therapy.

Lowe MC, Badell IR, Turner AP, Thompson PW, Leopardi FV, Strobert EA, Larsen CP, Kirk AD.

Am J Transplant. 2013 Feb;13(2):312-9. doi: 10.1111/j.1600-6143.2012.04341.x. Epub 2012 Dec 27.

PMID:
23279640
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Prolonged islet graft survival in NOD mice by blockade of the CD40-CD154 pathway of T-cell costimulation.

Molano RD, Berney T, Li H, Cattan P, Pileggi A, Vizzardelli C, Kenyon NS, Ricordi C, Burkly LC, Inverardi L.

Diabetes. 2001 Feb;50(2):270-6.

PMID:
11272136
[PubMed - indexed for MEDLINE]
Free Article
18.

Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways.

Cardona K, Korbutt GS, Milas Z, Lyon J, Cano J, Jiang W, Bello-Laborn H, Hacquoil B, Strobert E, Gangappa S, Weber CJ, Pearson TC, Rajotte RV, Larsen CP.

Nat Med. 2006 Mar;12(3):304-6. Epub 2006 Feb 26.

PMID:
16501570
[PubMed - indexed for MEDLINE]
19.

Anti-CD40 therapy extends renal allograft survival in rhesus macaques.

Pearson TC, Trambley J, Odom K, Anderson DC, Cowan S, Bray R, Lin A, Hollenbaugh D, Aruffo A, Siadak AW, Strobert E, Hennigar R, Larsen CP.

Transplantation. 2002 Oct 15;74(7):933-40.

PMID:
12394833
[PubMed - indexed for MEDLINE]
20.

ASKP1240, a fully human anti-CD40 monoclonal antibody, prolongs pancreatic islet allograft survival in nonhuman primates.

Watanabe M, Yamashita K, Suzuki T, Kamachi H, Kuraya D, Koshizuka Y, Ogura M, Yoshida T, Aoyagi T, Fukumori D, Shimamura T, Okimura K, Maeta K, Miura T, Sakai F, Todo S.

Am J Transplant. 2013 Aug;13(8):1976-88. doi: 10.1111/ajt.12330. Epub 2013 Jul 10.

PMID:
23841873
[PubMed - indexed for MEDLINE]
Free Article

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