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Results: 1 to 20 of 79

1.

Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.

van Eyk CL, O'Keefe LV, Lawlor KT, Samaraweera SE, McLeod CJ, Price GR, Venter DJ, Richards RI.

Hum Mol Genet. 2011 Jul 15;20(14):2783-94. doi: 10.1093/hmg/ddr177. Epub 2011 Apr 25.

PMID:
21518731
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases.

Lawlor KT, O'Keefe LV, Samaraweera SE, van Eyk CL, McLeod CJ, Maloney CA, Dang TH, Suter CM, Richards RI.

Hum Mol Genet. 2011 Oct 1;20(19):3757-68. doi: 10.1093/hmg/ddr292. Epub 2011 Jun 30.

PMID:
21724553
[PubMed - indexed for MEDLINE]
Free Article
3.

The pathogenic agent in Drosophila models of 'polyglutamine' diseases.

McLeod CJ, O'Keefe LV, Richards RI.

Hum Mol Genet. 2005 Apr 15;14(8):1041-8. Epub 2005 Mar 9.

PMID:
15757976
[PubMed - indexed for MEDLINE]
Free Article
4.

Genes and pathways affected by CAG-repeat RNA-based toxicity in Drosophila.

Shieh SY, Bonini NM.

Hum Mol Genet. 2011 Dec 15;20(24):4810-21. doi: 10.1093/hmg/ddr420. Epub 2011 Sep 20.

PMID:
21933837
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Perturbation of U2AF65/NXF1-mediated RNA nuclear export enhances RNA toxicity in polyQ diseases.

Tsoi H, Lau CK, Lau KF, Chan HY.

Hum Mol Genet. 2011 Oct 1;20(19):3787-97. doi: 10.1093/hmg/ddr297. Epub 2011 Jul 1.

PMID:
21725067
[PubMed - indexed for MEDLINE]
Free Article
6.

The conserved role of the AKT/GSK3 axis in cell survival and glycogen metabolism in Rhipicephalus (Boophilus) microplus embryo tick cell line BME26.

de Abreu LA, Calixto C, Waltero CF, Della Noce BP, Githaka NW, Seixas A, Parizi LF, Konnai S, Vaz Ida S, Ohashi K, Logullo C.

Biochim Biophys Acta. 2013 Mar;1830(3):2574-82.

PMID:
23274741
[PubMed - indexed for MEDLINE]
Free Article
7.

The spinocerebellar ataxia 8 noncoding RNA causes neurodegeneration and associates with staufen in Drosophila.

Mutsuddi M, Marshall CM, Benzow KA, Koob MD, Rebay I.

Curr Biol. 2004 Feb 17;14(4):302-8.

PMID:
14972680
[PubMed - indexed for MEDLINE]
Free Article
8.

Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target.

Krzyzosiak WJ, Sobczak K, Wojciechowska M, Fiszer A, Mykowska A, Kozlowski P.

Nucleic Acids Res. 2012 Jan;40(1):11-26. doi: 10.1093/nar/gkr729. Epub 2011 Sep 9. Review.

PMID:
21908410
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Modeling and analysis of repeat RNA toxicity in Drosophila.

Samaraweera SE, O'Keefe LV, van Eyk CL, Lawlor KT, Humphreys DT, Suter CM, Richards RI.

Methods Mol Biol. 2013;1017:173-92. doi: 10.1007/978-1-62703-438-8_13.

PMID:
23719916
[PubMed - indexed for MEDLINE]
10.

Neurodegeneration: RNA turns number one suspect in polyglutamine diseases.

Birman S.

Curr Biol. 2008 Aug 5;18(15):R659-R661. doi: 10.1016/j.cub.2008.06.023.

PMID:
18682207
[PubMed - indexed for MEDLINE]
Free Article
11.

Distinct roles for Toll and autophagy pathways in double-stranded RNA toxicity in a Drosophila model of expanded repeat neurodegenerative diseases.

Samaraweera SE, O'Keefe LV, Price GR, Venter DJ, Richards RI.

Hum Mol Genet. 2013 Jul 15;22(14):2811-9. doi: 10.1093/hmg/ddt130. Epub 2013 Mar 21.

PMID:
23525903
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ubiquitous expression of CUG or CAG trinucleotide repeat RNA causes common morphological defects in a Drosophila model of RNA-mediated pathology.

Lawlor KT, O'Keefe LV, Samaraweera SE, van Eyk CL, Richards RI.

PLoS One. 2012;7(6):e38516. doi: 10.1371/journal.pone.0038516. Epub 2012 Jun 8.

PMID:
22715390
[PubMed - in process]
Free PMC Article
13.

Muscleblind isoforms are functionally distinct and regulate alpha-actinin splicing.

Vicente M, Monferrer L, Poulos MG, Houseley J, Monckton DG, O'dell KM, Swanson MS, Artero RD.

Differentiation. 2007 Jun;75(5):427-40. Epub 2007 Feb 16.

PMID:
17309604
[PubMed - indexed for MEDLINE]
14.

Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy.

Yu Z, Teng X, Bonini NM.

PLoS Genet. 2011 Mar;7(3):e1001340. doi: 10.1371/journal.pgen.1001340. Epub 2011 Mar 17.

PMID:
21437269
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Repeat associated non-ATG translation initiation: one DNA, two transcripts, seven reading frames, potentially nine toxic entities!

Pearson CE.

PLoS Genet. 2011 Mar;7(3):e1002018. doi: 10.1371/journal.pgen.1002018. Epub 2011 Mar 10. Review.

PMID:
21423665
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Myotonic dystrophy associated expanded CUG repeat muscleblind positive ribonuclear foci are not toxic to Drosophila.

Houseley JM, Wang Z, Brock GJ, Soloway J, Artero R, Perez-Alonso M, O'Dell KM, Monckton DG.

Hum Mol Genet. 2005 Mar 15;14(6):873-83. Epub 2005 Feb 9.

PMID:
15703191
[PubMed - indexed for MEDLINE]
Free Article
17.

Role of non-coding RNAs in neurodegeneration and stress response in Drosophila.

Savvateeva-Popova E, Medvedeva A, Popov A, Evgen'ev M.

Biotechnol J. 2008 Aug;3(8):1010-21. doi: 10.1002/biot.200800120.

PMID:
18702036
[PubMed - indexed for MEDLINE]
18.

Neuronal activity and Wnt signaling act through Gsk3-beta to regulate axonal integrity in mature Drosophila olfactory sensory neurons.

Chiang A, Priya R, Ramaswami M, Vijayraghavan K, Rodrigues V.

Development. 2009 Apr;136(8):1273-82. doi: 10.1242/dev.031377.

PMID:
19304886
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling.

Yang Y, Gehrke S, Haque ME, Imai Y, Kosek J, Yang L, Beal MF, Nishimura I, Wakamatsu K, Ito S, Takahashi R, Lu B.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13670-5. Epub 2005 Sep 9.

PMID:
16155123
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Repeat length and RNA expression level are not primary determinants in CUG expansion toxicity in Drosophila models.

Le Mée G, Ezzeddine N, Capri M, Aït-Ahmed O.

PLoS One. 2008 Jan 23;3(1):e1466. doi: 10.1371/journal.pone.0001466.

PMID:
18213375
[PubMed - indexed for MEDLINE]
Free PMC Article

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