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Protein stability by number: high-throughput and statistical approaches to one of protein science's most difficult problems.

Magliery TJ, Lavinder JJ, Sullivan BJ.

Curr Opin Chem Biol. 2011 Jun;15(3):443-51. doi: 10.1016/j.cbpa.2011.03.015. Epub 2011 Apr 15. Review.


Stabilizing proteins from sequence statistics: the interplay of conservation and correlation in triosephosphate isomerase stability.

Sullivan BJ, Nguyen T, Durani V, Mathur D, Rojas S, Thomas M, Syu T, Magliery TJ.

J Mol Biol. 2012 Jul 20;420(4-5):384-99. doi: 10.1016/j.jmb.2012.04.025. Epub 2012 May 1.


Modulation of protein stability and aggregation properties by surface charge engineering.

Raghunathan G, Sokalingam S, Soundrarajan N, Madan B, Munussami G, Lee SG.

Mol Biosyst. 2013 Sep;9(9):2379-89. doi: 10.1039/c3mb70068b.


A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity.

Isom DG, Marguet PR, Oas TG, Hellinga HW.

Proteins. 2011 Apr;79(4):1034-47. doi: 10.1002/prot.22932. Epub 2011 Jan 5.


Engineering proteins with tunable thermodynamic and kinetic stabilities.

Pey AL, Rodriguez-Larrea D, Bomke S, Dammers S, Godoy-Ruiz R, Garcia-Mira MM, Sanchez-Ruiz JM.

Proteins. 2008 Apr;71(1):165-74.


High-throughput thermal scanning: a general, rapid dye-binding thermal shift screen for protein engineering.

Lavinder JJ, Hari SB, Sullivan BJ, Magliery TJ.

J Am Chem Soc. 2009 Mar 25;131(11):3794-5. doi: 10.1021/ja8049063.


Stability effects of mutations and protein evolvability.

Tokuriki N, Tawfik DS.

Curr Opin Struct Biol. 2009 Oct;19(5):596-604. doi: 10.1016/ Epub 2009 Sep 16. Review.


Assessing predictors of changes in protein stability upon mutation using self-consistency.

Thiltgen G, Goldstein RA.

PLoS One. 2012;7(10):e46084. doi: 10.1371/journal.pone.0046084. Epub 2012 Oct 29.


Structure- and sequence-analysis inspired engineering of proteins for enhanced thermostability.

Wijma HJ, Floor RJ, Janssen DB.

Curr Opin Struct Biol. 2013 Aug;23(4):588-94. doi: 10.1016/ Epub 2013 May 15. Review.


A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function.

Araya CL, Fowler DM, Chen W, Muniez I, Kelly JW, Fields S.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16858-63. doi: 10.1073/pnas.1209751109. Epub 2012 Oct 3.


Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details.

Potapov V, Cohen M, Schreiber G.

Protein Eng Des Sel. 2009 Sep;22(9):553-60. doi: 10.1093/protein/gzp030. Epub 2009 Jun 26.


Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity.

Isom DG, Vardy E, Oas TG, Hellinga HW.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4908-13. doi: 10.1073/pnas.0910421107. Epub 2010 Mar 1.


A method for direct measurement of protein stability in vivo.

Ignatova Z, Gierasch LM.

Methods Mol Biol. 2009;490:165-78. doi: 10.1007/978-1-59745-367-7_7.


Improving the stability of an antibody variable fragment by a combination of knowledge-based approaches: validation and mechanisms.

Monsellier E, Bedouelle H.

J Mol Biol. 2006 Sep 22;362(3):580-93. Epub 2006 Jul 28.


Consensus protein design without phylogenetic bias.

Jäckel C, Bloom JD, Kast P, Arnold FH, Hilvert D.

J Mol Biol. 2010 Jun 18;399(4):541-6. doi: 10.1016/j.jmb.2010.04.039. Epub 2010 Apr 28.


Automated, high-throughput platform for protein solubility screening using a split-GFP system.

Listwan P, Terwilliger TC, Waldo GS.

J Struct Funct Genomics. 2009 Mar;10(1):47-55. doi: 10.1007/s10969-008-9049-4. Epub 2008 Nov 28.


Robust prediction of mutation-induced protein stability change by property encoding of amino acids.

Kang S, Chen G, Xiao G.

Protein Eng Des Sel. 2009 Feb;22(2):75-83. doi: 10.1093/protein/gzn063. Epub 2008 Dec 2.


Local and long-range stability in tandemly arrayed tetratricopeptide repeats.

Main ER, Stott K, Jackson SE, Regan L.

Proc Natl Acad Sci U S A. 2005 Apr 19;102(16):5721-6. Epub 2005 Apr 11.

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