Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 110

1.

The utility of hydrogen/deuterium exchange mass spectrometry in biopharmaceutical comparability studies.

Houde D, Berkowitz SA, Engen JR.

J Pharm Sci. 2011 Jun;100(6):2071-86. doi: 10.1002/jps.22432. Epub 2010 Dec 29.

PMID:
21491437
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Characterization of IgG1 conformation and conformational dynamics by hydrogen/deuterium exchange mass spectrometry.

Houde D, Arndt J, Domeier W, Berkowitz S, Engen JR.

Anal Chem. 2009 Apr 1;81(7):2644-51. doi: 10.1021/ac802575y. Erratum in: Anal Chem. 2009 Jul 15;81(14):5966.

PMID:
19265386
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Hydra: software for tailored processing of H/D exchange data from MS or tandem MS analyses.

Slysz GW, Baker CA, Bozsa BM, Dang A, Percy AJ, Bennett M, Schriemer DC.

BMC Bioinformatics. 2009 May 27;10:162. doi: 10.1186/1471-2105-10-162.

PMID:
19473537
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Surrogate H/D detection strategy for protein conformational analysis using MS/MS data.

Percy AJ, Slysz GW, Schriemer DC.

Anal Chem. 2009 Oct 1;81(19):7900-7. doi: 10.1021/ac901148u.

PMID:
19681596
[PubMed - indexed for MEDLINE]
5.

Structural mass spectrometry in biologics discovery: advances and future trends.

Mo J, Tymiak AA, Chen G.

Drug Discov Today. 2012 Dec;17(23-24):1323-30. doi: 10.1016/j.drudis.2012.07.006. Epub 2012 Jul 20. Review.

PMID:
22819924
[PubMed - indexed for MEDLINE]
6.

High-resolution MS for structural characterization of protein therapeutics: advances and future directions.

Wei H, Tymiak AA, Chen G.

Bioanalysis. 2013 May;5(10):1299-313. doi: 10.4155/bio.13.80. Review.

PMID:
23721450
[PubMed - indexed for MEDLINE]
7.

Using hydrogen/deuterium exchange mass spectrometry to study conformational changes in granulocyte colony stimulating factor upon PEGylation.

Wei H, Ahn J, Yu YQ, Tymiak A, Engen JR, Chen G.

J Am Soc Mass Spectrom. 2012 Mar;23(3):498-504. doi: 10.1007/s13361-011-0310-x. Epub 2012 Jan 7.

PMID:
22227798
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Conformation and dynamics of biopharmaceuticals: transition of mass spectrometry-based tools from academe to industry.

Kaltashov IA, Bobst CE, Abzalimov RR, Berkowitz SA, Houde D.

J Am Soc Mass Spectrom. 2010 Mar;21(3):323-37. doi: 10.1016/j.jasms.2009.10.013. Epub 2009 Oct 29.

PMID:
19963397
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Probing protein interactions with hydrogen/deuterium exchange and mass spectrometry-a review.

Percy AJ, Rey M, Burns KM, Schriemer DC.

Anal Chim Acta. 2012 Apr 6;721:7-21. doi: 10.1016/j.aca.2012.01.037. Epub 2012 Jan 31. Review.

PMID:
22405295
[PubMed - indexed for MEDLINE]
10.

Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches.

Bobst CE, Abzalimov RR, Houde D, Kloczewiak M, Mhatre R, Berkowitz SA, Kaltashov IA.

Anal Chem. 2008 Oct 1;80(19):7473-81. doi: 10.1021/ac801214x. Epub 2008 Aug 27.

PMID:
18729476
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Restraining expansion of the peak envelope in H/D exchange-MS and its application in detecting perturbations of protein structure/dynamics.

Slysz GW, Percy AJ, Schriemer DC.

Anal Chem. 2008 Sep 15;80(18):7004-11. doi: 10.1021/ac800897q. Epub 2008 Aug 16.

PMID:
18707134
[PubMed - indexed for MEDLINE]
12.

Internal standards in the quantitative determination of protein biopharmaceuticals using liquid chromatography coupled to mass spectrometry.

Bronsema KJ, Bischoff R, van de Merbel NC.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Apr 15;893-894:1-14. doi: 10.1016/j.jchromb.2012.02.021. Epub 2012 Feb 21. Review.

PMID:
22426285
[PubMed - indexed for MEDLINE]
13.

H/D exchange centroid monitoring is insufficient to show differences in the behavior of protein states.

Zhang J, Ramachandran P, Kumar R, Gross ML.

J Am Soc Mass Spectrom. 2013 Mar;24(3):450-3. doi: 10.1007/s13361-012-0555-z. Epub 2013 Feb 9.

PMID:
23397137
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Quantitative assessment of protein structural models by comparison of H/D exchange MS data with exchange behavior accurately predicted by DXCOREX.

Liu T, Pantazatos D, Li S, Hamuro Y, Hilser VJ, Woods VL Jr.

J Am Soc Mass Spectrom. 2012 Jan;23(1):43-56. doi: 10.1007/s13361-011-0267-9. Epub 2011 Oct 20.

PMID:
22012689
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Probing protein structure and dynamics by hydrogen exchange-mass spectrometry.

Wang L, Smith DL.

Curr Protoc Protein Sci. 2002 Aug;Chapter 17:Unit 17.6. doi: 10.1002/0471140864.ps1706s28.

PMID:
18429224
[PubMed - indexed for MEDLINE]
16.

New developments in protein structure-function analysis by MS and use of hydrogen-deuterium exchange microfluidics.

Landreh M, Astorga-Wells J, Johansson J, Bergman T, J├Ârnvall H.

FEBS J. 2011 Oct;278(20):3815-21. doi: 10.1111/j.1742-4658.2011.08215.x. Epub 2011 Jul 5. Review.

PMID:
21668648
[PubMed - indexed for MEDLINE]
17.

Hydrogen-exchange mass spectrometry for the study of intrinsic disorder in proteins.

Balasubramaniam D, Komives EA.

Biochim Biophys Acta. 2013 Jun;1834(6):1202-9. doi: 10.1016/j.bbapap.2012.10.009. Epub 2012 Oct 22. Review.

PMID:
23099262
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

HDXFinder: automated analysis and data reporting of deuterium/hydrogen exchange mass spectrometry.

Miller DE, Prasannan CB, Villar MT, Fenton AW, Artigues A.

J Am Soc Mass Spectrom. 2012 Feb;23(2):425-9. doi: 10.1007/s13361-011-0234-5. Epub 2011 Nov 15.

PMID:
22083588
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Conformational changes in oxidatively stressed monoclonal antibodies studied by hydrogen exchange mass spectrometry.

Burkitt W, Domann P, O'Connor G.

Protein Sci. 2010 Apr;19(4):826-35. doi: 10.1002/pro.362.

PMID:
20162626
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data.

Pascal BD, Chalmers MJ, Busby SA, Mader CC, Southern MR, Tsinoremas NF, Griffin PR.

BMC Bioinformatics. 2007 May 16;8:156.

PMID:
17506883
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk