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Results: 1 to 20 of 142

1.

Flow cytometric analysis of mammalian glial cultures treated with methotrexate.

Serrano EE, Schimke RT.

Glia. 1990;3(6):539-49.

PMID:
2148556
[PubMed - indexed for MEDLINE]
2.

Selective overproduction of human dihydrofolate reductase in a methotrexate-resistant human-mouse somatic cell hybrid.

Sastry KJ, Chan TS, Rodriguez LV.

Biochem Biophys Res Commun. 1985 Oct 30;132(2):795-803.

PMID:
4062946
[PubMed - indexed for MEDLINE]
3.

A comparison of the propensity for gene amplification between near-tetraploid and near-diploid V79 clones resistant to 150 nM methotrexate.

Hashimoto MW, Nikaido O, Kobayashi N, Chang CC, Trosko JE, Mori T.

Carcinogenesis. 1996 Mar;17(3):389-94.

PMID:
8631121
[PubMed - indexed for MEDLINE]
Free Article
4.

Amplification of a polymorphic dihydrofolate reductase gene expressing an enzyme with decreased binding to methotrexate in a human colon carcinoma cell line, HCT-8R4, resistant to this drug.

Srimatkandada S, Schweitzer BI, Moroson BA, Dube S, Bertino JR.

J Biol Chem. 1989 Feb 25;264(6):3524-8.

PMID:
2914962
[PubMed - indexed for MEDLINE]
Free Article
5.
6.
7.

Mechanism of methotrexate-sensitivity of choriocarcinoma cells in culture.

Inoue T, Nagura E, Toyoda T, Ishizuka T, Gotoh S, Kawashima K, Tomoda Y, Nagai Y.

Jpn J Cancer Res. 1988 Mar;79(3):400-5.

PMID:
2836349
[PubMed - indexed for MEDLINE]
8.
9.

Transgenic mice expressing the tyr22 variant of murine DHFR: protection of transgenic marrow transplant recipients from lethal doses of methotrexate.

James RI, May C, Vagt MD, Studebaker R, McIvor RS.

Exp Hematol. 1997 Nov;25(12):1286-95.

PMID:
9357973
[PubMed - indexed for MEDLINE]
10.

[Mechanisms of development of resistance to methotrexate in choriocarcinoma cells].

Sakai K.

Hokkaido Igaku Zasshi. 1986 Sep;61(5):649-61. Japanese.

PMID:
3781466
[PubMed - indexed for MEDLINE]
12.

Transient inhibition of DNA synthesis by 5-fluorodeoxyuridine leads to overexpression of dihydrofolate reductase with increased frequency of methotrexate resistance.

Schuetz JD, Gorse KM, Goldman ID, Westin EH.

J Biol Chem. 1988 Jun 5;263(16):7708-12.

PMID:
2967290
[PubMed - indexed for MEDLINE]
Free Article
13.

Dihydrofolate reductase amplification and sensitization to methotrexate of methotrexate-resistant colon cancer cells.

Morales C, García MJ, Ribas M, Miró R, Muñoz M, Caldas C, Peinado MA.

Mol Cancer Ther. 2009 Feb;8(2):424-32. doi: 10.1158/1535-7163.MCT-08-0759. Epub 2009 Feb 3.

PMID:
19190117
[PubMed - indexed for MEDLINE]
Free Article
14.
15.

Modulation of dihydrofolate reductase gene expression in methotrexate-resistant human leukemia CCRF-CEM/E cells by antisense oligonucleotides.

Morganti M, Coronnello M, Caciagli B, Biondi C, Quattrone A, Capaccioli S, Mazzei T, Mini E.

Anticancer Drugs. 2000 Apr;11(4):285-94.

PMID:
10898545
[PubMed - indexed for MEDLINE]
16.
17.

Methotrexate exacerbates tumor progression in a murine model of chronic myeloid leukemia.

Sweeney CL, Diers MD, Frandsen JL, Gunther R, Verfaillie CM, McIvor RS.

J Pharmacol Exp Ther. 2002 Mar;300(3):1075-84.

PMID:
11861818
[PubMed - indexed for MEDLINE]
Free Article
18.

Efficient protection from methotrexate toxicity and selection of transduced human hematopoietic cells following gene transfer of dihydrofolate reductase mutants.

Meisel R, Bardenheuer W, Strehblow C, Sorg UR, Elmaagacli A, Seeber S, Flasshove M, Moritz T.

Exp Hematol. 2003 Dec;31(12):1215-22.

PMID:
14662327
[PubMed - indexed for MEDLINE]
19.

Methotrexate accumulates to similar levels in animals transplanted with normal versus drug-resistant transgenic marrow.

Belur LR, Boelk-Galvan D, Diers MD, McIvor RS, Zimmerman CL.

Cancer Res. 2001 Feb 15;61(4):1522-6.

PMID:
11245460
[PubMed - indexed for MEDLINE]
Free Article
20.

Phenotypic heterogeneity in cultured human head and neck squamous cell carcinoma lines with low-level methotrexate resistance.

Rosowsky A, Wright JE, Cucchi CA, Lippke JA, Tantravahi R, Ervin TJ, Frei E 3rd.

Cancer Res. 1985 Dec;45(12 Pt 1):6205-12.

PMID:
2415240
[PubMed - indexed for MEDLINE]
Free Article

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