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Results: 1 to 20 of 525

1.

Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.

Bleasdale JE, Thakur NR, Gremban RS, Bundy GL, Fitzpatrick FA, Smith RJ, Bunting S.

J Pharmacol Exp Ther. 1990 Nov;255(2):756-68.

PMID:
2147038
[PubMed - indexed for MEDLINE]
2.

Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness.

Smith RJ, Sam LM, Justen JM, Bundy GL, Bala GA, Bleasdale JE.

J Pharmacol Exp Ther. 1990 May;253(2):688-97.

PMID:
2338654
[PubMed - indexed for MEDLINE]
3.

U-73122, an aminosteroid phospholipase C inhibitor, may also block Ca2+ influx through phospholipase C-independent mechanism in neutrophil activation.

Wang JP.

Naunyn Schmiedebergs Arch Pharmacol. 1996 May;353(6):599-605.

PMID:
8738291
[PubMed - indexed for MEDLINE]
4.

7-[(1R,2S,3S,5R)-6,6-dimethyl-3-(4- iodobenzenesulfonylamino)bicyclo[3.1.1]hept-2-yl]-5(Z)-heptenoic acid: a novel high-affinity radiolabeled antagonist for platelet thromboxane A2/prostaglandin H2 receptors.

Naka M, Mais DE, Morinelli TA, Hamanaka N, Oatis JE Jr, Halushka PV.

J Pharmacol Exp Ther. 1992 Aug;262(2):632-7.

PMID:
1386885
[PubMed - indexed for MEDLINE]
5.

Characterization of the inhibition of U46619-mediated human platelet activation by the trimetoquinol isomers. Evidence for endoperoxide/thromboxane A2 receptor blockade.

Ahn CH, Romstedt KJ, Wallace LJ, Miller DD, Feller DR.

Biochem Pharmacol. 1988 Aug 1;37(15):3023-33.

PMID:
3134894
[PubMed - indexed for MEDLINE]
6.

Mechanism of inositol 1,4,5-trisphosphate-induced aggregation in saponin-permeabilized platelets.

Knezevic I, Dieter JP, Le Breton GC.

J Pharmacol Exp Ther. 1992 Mar;260(3):947-55.

PMID:
1545407
[PubMed - indexed for MEDLINE]
7.
8.

Labeling of human platelet plasma membrane thromboxane A2/prostaglandin H2 receptors using SQB, a novel biotinylated receptor probe.

Komiotis D, Wencel-Drake JD, Dieter JP, Lim CT, Le Breton GC.

Biochem Pharmacol. 1996 Sep 13;52(5):763-70.

PMID:
8765474
[PubMed - indexed for MEDLINE]
9.

Thromboxane A2-mediated shape change: independent of Gq-phospholipase C--Ca2+ pathway in rabbit platelets.

Ohkubo S, Nakahata N, Ohizumi Y.

Br J Pharmacol. 1996 Mar;117(6):1095-104.

PMID:
8882602
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The response to thromboxane A2 analogues in human platelets. Discrimination of two binding sites linked to distinct effector systems.

Takahara K, Murray R, FitzGerald GA, Fitzgerald DJ.

J Biol Chem. 1990 Apr 25;265(12):6836-44.

PMID:
2139029
[PubMed - indexed for MEDLINE]
Free Article
11.

Human platelet activation by bacterial phospholipase C is mediated by phosphatidylinositol hydrolysis but not generation of phosphatidic acid: inhibition by a selective inhibitor of phospholipase C.

Navran SS, Romstedt K, Chang J, Miller DD, Feller DR, Huzoor-Akbar.

Thromb Res. 1984 Mar 1;33(5):499-510.

PMID:
6372157
[PubMed - indexed for MEDLINE]
12.

Synthesis and in vitro activity of various derivatives of a novel thromboxane receptor antagonist, (+/-)-(5Z)-7-[3-endo-[(phenylsulfonyl)amino]bicyclo[2.2.1] hept-2-exo-yl]heptenoic acid.

Narisada M, Ohtani M, Watanabe F, Uchida K, Arita H, Doteuchi M, Hanasaki K, Kakushi H, Otani K, Hara S.

J Med Chem. 1988 Sep;31(9):1847-54.

PMID:
2970551
[PubMed - indexed for MEDLINE]
13.

Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.

Yu SM, Wu TS, Teng CM.

Br J Pharmacol. 1994 Mar;111(3):906-12.

PMID:
8019768
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Phenol red is a thromboxane A2/prostaglandin H2 receptor antagonist in canine lingual arteries and human platelets.

Greenberg SS, Johns A, Kleha J, Xie J, Wang Y, Bianchi J, Conley K.

J Pharmacol Exp Ther. 1994 Mar;268(3):1352-61.

PMID:
8138950
[PubMed - indexed for MEDLINE]
16.

The phospholipase C inhibitor U73122 inhibits phorbol ester-induced platelet activation.

Lockhart LK, McNicol A.

J Pharmacol Exp Ther. 1999 May;289(2):721-8.

PMID:
10215645
[PubMed - indexed for MEDLINE]
Free Article
17.

U-73122: a potent inhibitor of human polymorphonuclear neutrophil adhesion on biological surfaces and adhesion-related effector functions.

Smith RJ, Justen JM, McNab AR, Rosenbloom CL, Steele AN, Detmers PA, Anderson DC, Manning AM.

J Pharmacol Exp Ther. 1996 Jul;278(1):320-9.

PMID:
8764366
[PubMed - indexed for MEDLINE]
18.

Inhibition of human platelets and polymorphonuclear neutrophils by the potent and metabolically stable prostaglandin D2 analog ZK 118.182.

Darius H, Michael-Hepp J, Thierauch KH, Fisch A.

Eur J Pharmacol. 1994 Jun 13;258(3):207-13.

PMID:
7522176
[PubMed - indexed for MEDLINE]
19.
20.

Platelet desensitization by arachidonic acid is associated with the suppression of endoperoxide/thromboxane A2 binding to the membrane receptor.

Sato T, Hashizume T, Nakao K, Akiba S, Fujii T.

Biochim Biophys Acta. 1989 Aug 18;992(2):168-73.

PMID:
2503041
[PubMed - indexed for MEDLINE]

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