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Similar articles for PubMed (Select 21469089)


Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses.

Wu GF, Corbo E, Schmidt M, Smith-Garvin JE, Riese MJ, Jordan MS, Laufer TM, Brown EJ, Maltzman JS.

Eur J Immunol. 2011 Jul;41(7):2064-73. doi: 10.1002/eji.201040809. Epub 2011 Jun 7.


Ablation of SLP-76 signaling after T cell priming generates memory CD4 T cells impaired in steady-state and cytokine-driven homeostasis.

Bushar ND, Corbo E, Schmidt M, Maltzman JS, Farber DL.

Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):827-31. doi: 10.1073/pnas.0908126107. Epub 2009 Dec 22.


The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells.

Baker RG, Hsu CJ, Lee D, Jordan MS, Maltzman JS, Hammer DA, Baumgart T, Koretzky GA.

Mol Cell Biol. 2009 Oct;29(20):5578-89. doi: 10.1128/MCB.00283-09. Epub 2009 Aug 10.


Conditional deletion reveals a cell-autonomous requirement of SLP-76 for thymocyte selection.

Maltzman JS, Kovoor L, Clements JL, Koretzky GA.

J Exp Med. 2005 Oct 3;202(7):893-900. Epub 2005 Sep 26.


The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in thymic selection and T-cell activation.

Shen S, Lau J, Zhu M, Zou J, Fuller D, Li QJ, Zhang W.

Blood. 2009 Jul 2;114(1):74-84. doi: 10.1182/blood-2008-09-177832. Epub 2009 Apr 28.


The SLP-76 Src homology 2 domain is required for T cell development and activation.

Burns JC, Corbo E, Degen J, Gohil M, Anterasian C, Schraven B, Koretzky GA, Kliche S, Jordan MS.

J Immunol. 2011 Nov 1;187(9):4459-66. doi: 10.4049/jimmunol.0903379. Epub 2011 Sep 26.


Quantitative phosphoproteomics reveals SLP-76 dependent regulation of PAG and Src family kinases in T cells.

Cao L, Ding Y, Hung N, Yu K, Ritz A, Raphael BJ, Salomon AR.

PLoS One. 2012;7(10):e46725. doi: 10.1371/journal.pone.0046725. Epub 2012 Oct 11.


Impaired thymic selection in mice expressing altered levels of the SLP-76 adaptor protein.

Ramsey K, Luckashenak N, Koretzky GA, Clements JL.

J Leukoc Biol. 2008 Feb;83(2):419-29. Epub 2007 Oct 26.


Homeostatic division is not necessary for antigen-specific CD4+ memory T cell persistence.

Corbo-Rodgers E, Wiehagen KR, Staub ES, Maltzman JS.

J Immunol. 2012 Oct 1;189(7):3378-85. Epub 2012 Sep 5.


Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells.

Wiehagen KR, Corbo E, Schmidt M, Shin H, Wherry EJ, Maltzman JS.

Blood. 2010 Dec 16;116(25):5560-70. doi: 10.1182/blood-2010-06-292458. Epub 2010 Sep 30.


Cutting edge: rescue of pre-TCR but not mature TCR signaling in mice expressing membrane-targeted SLP-76.

Bezman NA, Baker RG, Lenox LE, Jordan MS, Koretzky GA.

J Immunol. 2009 May 1;182(9):5183-7. doi: 10.4049/jimmunol.0802176.


HIV-1 Nef limits communication between linker of activated T cells and SLP-76 to reduce formation of SLP-76-signaling microclusters following TCR stimulation.

Abraham L, Bankhead P, Pan X, Engel U, Fackler OT.

J Immunol. 2012 Aug 15;189(4):1898-910. doi: 10.4049/jimmunol.1200652. Epub 2012 Jul 16.


The chemokine CXCL12 generates costimulatory signals in T cells to enhance phosphorylation and clustering of the adaptor protein SLP-76.

Smith X, Schneider H, Köhler K, Liu H, Lu Y, Rudd CE.

Sci Signal. 2013 Jul 30;6(286):ra65. doi: 10.1126/scisignal.2004018.


Differential requirement for SLP-76 domains in T cell development and function.

Myung PS, Derimanov GS, Jordan MS, Punt JA, Liu QH, Judd BA, Meyers EE, Sigmund CD, Freedman BD, Koretzky GA.

Immunity. 2001 Dec;15(6):1011-26.


Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses.

Shui JW, Boomer JS, Han J, Xu J, Dement GA, Zhou G, Tan TH.

Nat Immunol. 2007 Jan;8(1):84-91. Epub 2006 Nov 19.


Differential SLP-76 expression and TCR-mediated signaling in effector and memory CD4 T cells.

Hussain SF, Anderson CF, Farber DL.

J Immunol. 2002 Feb 15;168(4):1557-65.


HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion.

Patzak IM, Königsberger S, Suzuki A, Mak TW, Kiefer F.

Eur J Immunol. 2010 Nov;40(11):3220-5. doi: 10.1002/eji.201040313.


In vivo disruption of T cell development by expression of a dominant-negative polypeptide designed to abolish the SLP-76/Gads interaction.

Jordan MS, Maltzman JS, Kliche S, Shabason J, Smith JE, Obstfeld A, Schraven B, Koretzky GA.

Eur J Immunol. 2007 Oct;37(10):2961-72.


Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody production.

Sonnenberg GF, Mangan PR, Bezman NA, Sekiguchi DR, Luning Prak ET, Erikson J, Maltzman JS, Jordan MS, Koretzky GA.

Blood. 2010 Mar 18;115(11):2186-95. doi: 10.1182/blood-2009-08-237438. Epub 2009 Dec 22.

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