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Results: 1 to 20 of 168

Related Citations for PubMed (Select 21458415)

1.

Topoisomerase I/II inhibition by a novel naphthoquinone containing a modified anthracycline ring system.

Kennedy S, DiCesare JC, Sheaff RJ.

Biochem Biophys Res Commun. 2011 Apr 29;408(1):94-8. doi: 10.1016/j.bbrc.2011.03.126. Epub 2011 Mar 30.

PMID:
21458415
2.

Topoisomerase I inactivation by a novel thiol reactive naphthoquinone.

Kennedy S, Dicesare JC, Sheaff RJ.

Biochem Biophys Res Commun. 2011 Jun 24;410(1):152-8. doi: 10.1016/j.bbrc.2011.05.131. Epub 2011 May 27.

PMID:
21651895
3.

Induction of cell death by a novel naphthoquinone containing a modified anthracycline ring system.

Carvajal D, Kennedy S, Boustani A, Lazar M, Nguyen S, DiCesare JC, Sheaff RJ.

Chem Biol Drug Des. 2011 Nov;78(5):764-77. doi: 10.1111/j.1747-0285.2011.01214.x. Epub 2011 Sep 26.

PMID:
21838760
4.

Recent advances in the development of dual topoisomerase I and II inhibitors as anticancer drugs.

Salerno S, Da Settimo F, Taliani S, Simorini F, La Motta C, Fornaciari G, Marini AM.

Curr Med Chem. 2010;17(35):4270-90. Review.

PMID:
20939813
5.

Luciferase inhibition by a novel naphthoquinone.

Bedford R, LePage D, Hoffmann R, Kennedy S, Gutschenritter T, Bull L, Sujijantarat N, DiCesare JC, Sheaff RJ.

J Photochem Photobiol B. 2012 Feb 6;107:55-64. doi: 10.1016/j.jphotobiol.2011.11.008. Epub 2011 Dec 8.

PMID:
22197716
6.

Synthesis and biological activities of topopyrones.

Zaleski PA, Maini R, Leiris SJ, Elban MA, Hecht SM.

J Nat Prod. 2012 Apr 27;75(4):577-85. doi: 10.1021/np200777z. Epub 2012 Mar 30.

PMID:
22462811
7.

Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.

Zhuo ST, Li CY, Hu MH, Chen SB, Yao PF, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS.

Org Biomol Chem. 2013 Jun 28;11(24):3989-4005. doi: 10.1039/c3ob40325d.

PMID:
23657605
8.

Synthesis and evaluation of novel ellipticines as potential anti-cancer agents.

Deane FM, O'Sullivan EC, Maguire AR, Gilbert J, Sakoff JA, McCluskey A, McCarthy FO.

Org Biomol Chem. 2013 Feb 28;11(8):1334-44. doi: 10.1039/c2ob27186a.

PMID:
23314103
9.

Synthesis, cytotoxicity and topoisomerase inhibition properties of multifarious aminoalkylated indeno[1,2-c]isoquinolin-5,11-diones.

Ahn G, Schifano-Faux N, Goossens JF, Baldeyrou B, Couture A, Grandclaudon P, Lansiaux A, Ryckebusch A.

Bioorg Med Chem Lett. 2011 Apr 15;21(8):2259-63. doi: 10.1016/j.bmcl.2011.02.106. Epub 2011 Mar 1.

PMID:
21439821
10.

Synthesis and biological evaluation of N-substituted benzo[c]phenanthrolines and benzo[c]phenanthrolinones as antiproliferative agents.

Genès C, Lenglet G, Depauw S, Nhili R, Prado S, David-Cordonnier MH, Michel S, Tillequin F, Porée FH.

Eur J Med Chem. 2011 Jun;46(6):2117-31. doi: 10.1016/j.ejmech.2011.02.065. Epub 2011 Mar 23.

PMID:
21435753
11.

2,4-Diaryl-5,6-dihydro-1,10-phenanthroline and 2,4-diaryl-5,6-dihydrothieno[2,3-h] quinoline derivatives for topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.

Thapa P, Karki R, Yoo HY, Park PH, Lee E, Jeon KH, Na Y, Cho WJ, Kwon Y, Lee ES.

Bioorg Chem. 2012 Feb;40(1):67-78. doi: 10.1016/j.bioorg.2011.09.001. Epub 2011 Sep 8.

PMID:
22000119
12.

Pyrroloquinolinone-based dual topoisomerase I/II inhibitor.

Dalla Via L, Marzaro G, Ferrarese A, Gia O, Chilin A.

Eur J Med Chem. 2014 Apr 22;77:103-9. doi: 10.1016/j.ejmech.2014.02.064. Epub 2014 Mar 1.

PMID:
24631729
13.

Design and synthesis of heterobimetallic topoisomerase I and II inhibitor complexes: in vitro DNA binding, interaction with 5'-GMP and 5'-TMP and cleavage studies.

Arjmand F, Muddassir M.

J Photochem Photobiol B. 2010 Oct 5;101(1):37-46. doi: 10.1016/j.jphotobiol.2010.06.009. Epub 2010 Jun 30.

PMID:
20638859
14.

Chiral ruthenium(II) anthraquinone complexes as dual inhibitors of topoisomerases I and II.

Kou JF, Qian C, Wang JQ, Chen X, Wang LL, Chao H, Ji LN.

J Biol Inorg Chem. 2012 Jan;17(1):81-96. doi: 10.1007/s00775-011-0831-6. Epub 2011 Aug 21.

PMID:
21858685
15.

Synthesis of benzo-annulated tryptanthrins and their biological properties.

Liang JL, Park SE, Kwon Y, Jahng Y.

Bioorg Med Chem. 2012 Aug 15;20(16):4962-7. doi: 10.1016/j.bmc.2012.06.034. Epub 2012 Jul 2.

PMID:
22819942
16.

Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.

Thapa U, Thapa P, Karki R, Yun M, Choi JH, Jahng Y, Lee E, Jeon KH, Na Y, Ha EM, Cho WJ, Kwon Y, Lee ES.

Eur J Med Chem. 2011 Aug;46(8):3201-9. doi: 10.1016/j.ejmech.2011.04.029. Epub 2011 Apr 29.

PMID:
21601964
17.

New topoisomerases inhibitors: synthesis of rutaecarpine derivatives and their inhibitory activity against topoisomerases.

Kim SI, Lee SH, Lee ES, Lee CS, Jahng Y.

Arch Pharm Res. 2012 May;35(5):785-9. doi: 10.1007/s12272-012-0504-1. Epub 2012 May 29.

PMID:
22644846
18.

Inhibition of human topoisomerases I and II by simocyclinone D8.

Oppegard LM, Nguyen T, Ellis KC, Hiasa H.

J Nat Prod. 2012 Aug 24;75(8):1485-9. doi: 10.1021/np300299y. Epub 2012 Aug 6.

PMID:
22867097
19.

Synthesis and biological evaluation of novel naphthoquinone fused cyclic aminoalkylphosphonates and aminoalkylphosphonic monoester.

Wang B, Miao ZW, Wang J, Chen RY, Zhang XD.

Amino Acids. 2008 Aug;35(2):463-8. Epub 2007 Jul 31.

PMID:
17665273
20.

Novel N-4-piperazinyl-ciprofloxacin-chalcone hybrids: synthesis, physicochemical properties, anticancer and topoisomerase I and II inhibitory activity.

Abdel-Aziz M, Park SE, Abuo-Rahma Gel-D, Sayed MA, Kwon Y.

Eur J Med Chem. 2013 Nov;69:427-38. doi: 10.1016/j.ejmech.2013.08.040. Epub 2013 Sep 12.

PMID:
24090914
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