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Items: 1 to 20 of 110

1.

Global phosphoproteomics reveals crosstalk between Bcr-Abl and negative feedback mechanisms controlling Src signaling.

Rubbi L, Titz B, Brown L, Galvan E, Komisopoulou E, Chen SS, Low T, Tahmasian M, Skaggs B, Müschen M, Pellegrini M, Graeber TG.

Sci Signal. 2011 Mar 29;4(166):ra18. doi: 10.1126/scisignal.2001314.

2.

Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells.

Wu J, Meng F, Lu H, Kong L, Bornmann W, Peng Z, Talpaz M, Donato NJ.

Blood. 2008 Apr 1;111(7):3821-9. doi: 10.1182/blood-2007-08-109330. Epub 2008 Jan 30.

3.

Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells.

Gioia R, Leroy C, Drullion C, Lagarde V, Etienne G, Dulucq S, Lippert E, Roche S, Mahon FX, Pasquet JM.

Blood. 2011 Aug 25;118(8):2211-21. doi: 10.1182/blood-2010-10-313692. Epub 2011 Jul 5.

4.

An inhibitor-resistant mutant of Hck protects CML cells against the antiproliferative and apoptotic effects of the broad-spectrum Src family kinase inhibitor A-419259.

Pene-Dumitrescu T, Peterson LF, Donato NJ, Smithgall TE.

Oncogene. 2008 Nov 27;27(56):7055-69. doi: 10.1038/onc.2008.330. Epub 2008 Sep 15.

5.

The Src family kinase Hck interacts with Bcr-Abl by a kinase-independent mechanism and phosphorylates the Grb2-binding site of Bcr.

Warmuth M, Bergmann M, Priess A, Häuslmann K, Emmerich B, Hallek M.

J Biol Chem. 1997 Dec 26;272(52):33260-70.

6.

Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells.

Chatain N, Ziegler P, Fahrenkamp D, Jost E, Moriggl R, Schmitz-Van de Leur H, Müller-Newen G.

Oncogene. 2013 Aug 1;32(31):3587-97. doi: 10.1038/onc.2012.369. Epub 2012 Aug 27.

PMID:
22926520
7.

Association between imatinib-resistant BCR-ABL mutation-negative leukemia and persistent activation of LYN kinase.

Wu J, Meng F, Kong LY, Peng Z, Ying Y, Bornmann WG, Darnay BG, Lamothe B, Sun H, Talpaz M, Donato NJ.

J Natl Cancer Inst. 2008 Jul 2;100(13):926-39. doi: 10.1093/jnci/djn188. Epub 2008 Jun 24.

8.

A computational model for early events in B cell antigen receptor signaling: analysis of the roles of Lyn and Fyn.

Barua D, Hlavacek WS, Lipniacki T.

J Immunol. 2012 Jul 15;189(2):646-58. doi: 10.4049/jimmunol.1102003. Epub 2012 Jun 18.

9.

Crosstalk between BCR/ABL oncoprotein and CXCR4 signaling through a Src family kinase in human leukemia cells.

Ptasznik A, Urbanowska E, Chinta S, Costa MA, Katz BA, Stanislaus MA, Demir G, Linnekin D, Pan ZK, Gewirtz AM.

J Exp Med. 2002 Sep 2;196(5):667-78.

11.

Effects of dasatinib on SRC kinase activity and downstream intracellular signaling in primitive chronic myelogenous leukemia hematopoietic cells.

Konig H, Copland M, Chu S, Jove R, Holyoake TL, Bhatia R.

Cancer Res. 2008 Dec 1;68(23):9624-33. doi: 10.1158/0008-5472.CAN-08-1131.

12.

Detection of a rare BCR-ABL tyrosine kinase fusion protein in H929 multiple myeloma cells using immunoprecipitation (IP)-tandem mass spectrometry (MS/MS).

Breitkopf SB, Yuan M, Pihan GA, Asara JM.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16190-5. doi: 10.1073/pnas.1212759109. Epub 2012 Sep 17.

13.
14.

Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.

Wilson MB, Schreiner SJ, Choi HJ, Kamens J, Smithgall TE.

Oncogene. 2002 Nov 21;21(53):8075-88.

15.

Protein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor Kinase.

Fan G, Aleem S, Yang M, Miller WT, Tonks NK.

J Biol Chem. 2015 Jun 26;290(26):15934-47. doi: 10.1074/jbc.M115.651703. Epub 2015 Apr 20.

16.

Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation.

Gishizky ML, Cortez D, Pendergast AM.

Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):10889-93.

17.
18.

Progressive changes in the leukemogenic signaling in BCR/ABL-transformed cells.

Nieborowska-Skorska M, Slupianek A, Skorski T.

Oncogene. 2000 Aug 24;19(36):4117-24.

19.

The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells.

Klejman A, Schreiner SJ, Nieborowska-Skorska M, Slupianek A, Wilson M, Smithgall TE, Skorski T.

EMBO J. 2002 Nov 1;21(21):5766-74.

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