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Results: 1 to 20 of 151

1.

α-Mangostin induces apoptosis in human chondrosarcoma cells through downregulation of ERK/JNK and Akt signaling pathway.

Krajarng A, Nakamura Y, Suksamrarn S, Watanapokasin R.

J Agric Food Chem. 2011 May 25;59(10):5746-54. doi: 10.1021/jf200620n. Epub 2011 Apr 11.

PMID:
21446759
[PubMed - indexed for MEDLINE]
2.

Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells.

Nakagawa Y, Iinuma M, Naoe T, Nozawa Y, Akao Y.

Bioorg Med Chem. 2007 Aug 15;15(16):5620-8. Epub 2007 May 18.

PMID:
17553685
[PubMed - indexed for MEDLINE]
3.

Alpha-mangostin suppresses PC-3 human prostate carcinoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen expression through the JNK signaling pathway.

Hung SH, Shen KH, Wu CH, Liu CL, Shih YW.

J Agric Food Chem. 2009 Feb 25;57(4):1291-8. doi: 10.1021/jf8032683.

PMID:
19178296
[PubMed - indexed for MEDLINE]
4.

Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.

Eur J Pharmacol. 2007 Jun 1;563(1-3):49-60. Epub 2007 Feb 8.

PMID:
17341418
[PubMed - indexed for MEDLINE]
6.

Alpha-mangostin induces Ca2+-ATPase-dependent apoptosis via mitochondrial pathway in PC12 cells.

Sato A, Fujiwara H, Oku H, Ishiguro K, Ohizumi Y.

J Pharmacol Sci. 2004 May;95(1):33-40.

PMID:
15153648
[PubMed - indexed for MEDLINE]
Free Article
7.

Antiproliferative effect of α-mangostin on canine osteosarcoma cells.

Krajarng A, Nilwarankoon S, Suksamrarn S, Watanapokasin R.

Res Vet Sci. 2012 Oct;93(2):788-94. doi: 10.1016/j.rvsc.2012.01.015. Epub 2012 Feb 17.

PMID:
22342127
[PubMed - indexed for MEDLINE]
8.

α-Mangostin induces mitochondrial dependent apoptosis in human hepatoma SK-Hep-1 cells through inhibition of p38 MAPK pathway.

Hsieh SC, Huang MH, Cheng CW, Hung JH, Yang SF, Hsieh YH.

Apoptosis. 2013 Dec;18(12):1548-60. doi: 10.1007/s10495-013-0888-5.

PMID:
23912717
[PubMed - indexed for MEDLINE]
9.

Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt.

Moon DO, Park SY, Heo MS, Kim KC, Park C, Ko WS, Choi YH, Kim GY.

Int Immunopharmacol. 2006 Dec 5;6(12):1796-807. Epub 2006 Aug 22.

PMID:
17052670
[PubMed - indexed for MEDLINE]
10.

Sorafenib induces growth inhibition and apoptosis of human chondrosarcoma cells by blocking the RAF/ERK/MEK pathway.

Lu X, Tang X, Guo W, Ren T, Zhao H.

J Surg Oncol. 2010 Dec 1;102(7):821-6. doi: 10.1002/jso.21661.

PMID:
20812347
[PubMed - indexed for MEDLINE]
11.

Selenocystine induces S-phase arrest and apoptosis in human breast adenocarcinoma MCF-7 cells by modulating ERK and Akt phosphorylation.

Chen T, Wong YS.

J Agric Food Chem. 2008 Nov 26;56(22):10574-81. doi: 10.1021/jf802125t.

PMID:
18959417
[PubMed - indexed for MEDLINE]
12.

JNK and ERK mitogen-activated protein kinases mediate THDA-induced apoptosis in K562 cells.

Yang SH, Wu ZZ, Chien CM, Lo YH, Wu MJ, Chang LS, Lin SR.

Cell Biol Toxicol. 2008 Aug;24(4):291-302. Epub 2007 Oct 13.

PMID:
17934787
[PubMed - indexed for MEDLINE]
13.

The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells.

Nguyen TT, Tran E, Nguyen TH, Do PT, Huynh TH, Huynh H.

Carcinogenesis. 2004 May;25(5):647-59. Epub 2003 Dec 19.

PMID:
14688022
[PubMed - indexed for MEDLINE]
Free Article
14.

Ketoconazole-induced JNK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells.

Lin KL, Huang CC, Cheng JS, Tsai JY, Lu YC, Chang HT, Jan CR.

Toxicol In Vitro. 2009 Oct;23(7):1268-76. doi: 10.1016/j.tiv.2009.07.025. Epub 2009 Jul 23.

PMID:
19631732
[PubMed - indexed for MEDLINE]
15.

Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt.

Sunters A, Madureira PA, Pomeranz KM, Aubert M, Brosens JJ, Cook SJ, Burgering BM, Coombes RC, Lam EW.

Cancer Res. 2006 Jan 1;66(1):212-20.

PMID:
16397234
[PubMed - indexed for MEDLINE]
Free Article
16.

Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells.

Moon DO, Lee KJ, Choi YH, Kim GY.

Int Immunopharmacol. 2007 Aug;7(8):1044-53. Epub 2007 Apr 26.

PMID:
17570321
[PubMed - indexed for MEDLINE]
18.

Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.

Yang R, Piperdi S, Gorlick R.

Clin Cancer Res. 2008 Oct 15;14(20):6396-404. doi: 10.1158/1078-0432.CCR-07-5113.

PMID:
18927278
[PubMed - indexed for MEDLINE]
Free Article
19.

Eriocalyxin B induces apoptosis in lymphoma cells through multiple cellular signaling pathways.

Zhang YW, Jiang XX, Chen QS, Shi WY, Wang L, Sun HD, Shen ZX, Chen Z, Chen SJ, Zhao WL.

Exp Hematol. 2010 Mar;38(3):191-201. doi: 10.1016/j.exphem.2009.12.005. Epub 2010 Jan 4.

PMID:
20045442
[PubMed - indexed for MEDLINE]
20.

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