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Items: 1 to 20 of 117

1.

Recovery from mu-opioid receptor desensitization after chronic treatment with morphine and methadone.

Quillinan N, Lau EK, Virk M, von Zastrow M, Williams JT.

J Neurosci. 2011 Mar 23;31(12):4434-43. doi: 10.1523/JNEUROSCI.4874-10.2011.

2.

Cellular morphine tolerance produced by βarrestin-2-dependent impairment of μ-opioid receptor resensitization.

Dang VC, Chieng B, Azriel Y, Christie MJ.

J Neurosci. 2011 May 11;31(19):7122-30. doi: 10.1523/JNEUROSCI.5999-10.2011.

3.

Remifentanil produces cross-desensitization and tolerance with morphine on the mu-opioid receptor.

Nowoczyn M, Marie N, Coulbault L, Hervault M, Davis A, Hanouz JL, Allouche S.

Neuropharmacology. 2013 Oct;73:368-79. doi: 10.1016/j.neuropharm.2013.06.010. Epub 2013 Jun 21.

PMID:
23792280
4.

Opioid agonists have different efficacy profiles for G protein activation, rapid desensitization, and endocytosis of mu-opioid receptors.

Borgland SL, Connor M, Osborne PB, Furness JB, Christie MJ.

J Biol Chem. 2003 May 23;278(21):18776-84. Epub 2003 Mar 17.

6.

Chronic morphine treatment inhibits opioid receptor desensitization and internalization.

Eisinger DA, Ammer H, Schulz R.

J Neurosci. 2002 Dec 1;22(23):10192-200.

7.

Chronic morphine treatment reduces recovery from opioid desensitization.

Dang VC, Williams JT.

J Neurosci. 2004 Sep 1;24(35):7699-706.

8.

Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons.

Bailey CP, Oldfield S, Llorente J, Caunt CJ, Teschemacher AG, Roberts L, McArdle CA, Smith FL, Dewey WL, Kelly E, Henderson G.

Br J Pharmacol. 2009 Sep;158(1):157-64. doi: 10.1111/j.1476-5381.2009.00140.x. Epub 2009 Mar 20.

9.

Differential activation and trafficking of micro-opioid receptors in brain slices.

Arttamangkul S, Quillinan N, Low MJ, von Zastrow M, Pintar J, Williams JT.

Mol Pharmacol. 2008 Oct;74(4):972-9. doi: 10.1124/mol.108.048512. Epub 2008 Jul 8.

11.
12.

Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice.

Morinville A, Cahill CM, Esdaile MJ, Aibak H, Collier B, Kieffer BL, Beaudet A.

J Neurosci. 2003 Jun 15;23(12):4888-98.

13.

Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons.

Yu YJ, Arttamangkul S, Evans CJ, Williams JT, von Zastrow M.

J Neurosci. 2009 Jan 7;29(1):222-33. doi: 10.1523/JNEUROSCI.4315-08.2009.

14.

Mu-opioid receptor desensitization in mature rat neurons: lack of interaction between DAMGO and morphine.

Bailey CP, Couch D, Johnson E, Griffiths K, Kelly E, Henderson G.

J Neurosci. 2003 Nov 19;23(33):10515-20.

15.

Two distinct mechanisms mediate acute mu-opioid receptor desensitization in native neurons.

Dang VC, Napier IA, Christie MJ.

J Neurosci. 2009 Mar 11;29(10):3322-7. doi: 10.1523/JNEUROSCI.4749-08.2009.

16.

mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin.

Lowe JD, Celver JP, Gurevich VV, Chavkin C.

J Biol Chem. 2002 May 3;277(18):15729-35. Epub 2002 Feb 22.

17.

Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness.

Zhang J, Ferguson SS, Barak LS, Bodduluri SR, Laporte SA, Law PY, Caron MG.

Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7157-62.

18.

Prolonged stimulation of μ-opioid receptors produces β-arrestin-2-mediated heterologous desensitization of α(2)-adrenoceptor function in locus ceruleus neurons.

Dang VC, Chieng BC, Christie MJ.

Mol Pharmacol. 2012 Sep;82(3):473-80. doi: 10.1124/mol.112.079350. Epub 2012 Jun 11.

19.

Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization.

Lowe JD, Sanderson HS, Cooke AE, Ostovar M, Tsisanova E, Withey SL, Chavkin C, Husbands SM, Kelly E, Henderson G, Bailey CP.

Mol Pharmacol. 2015 Aug;88(2):347-56. doi: 10.1124/mol.115.098293. Epub 2015 May 26.

PMID:
26013542
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