Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 135

Similar articles for PubMed (Select 21426022)

1.

The Mycobacterium tuberculosis cytochromes P450: physiology, biochemistry & molecular intervention.

McLean KJ, Belcher J, Driscoll MD, Fernandez CC, Le Van D, Bui S, Golovanova M, Munro AW.

Future Med Chem. 2010 Aug;2(8):1339-53. doi: 10.4155/fmc.10.216. Review.

PMID:
21426022
2.

Cytochromes P450: novel drug targets in the war against multidrug-resistant Mycobacterium tuberculosis.

Munro AW, McLean KJ, Marshall KR, Warman AJ, Lewis G, Roitel O, Sutcliffe MJ, Kemp CA, Modi S, Scrutton NS, Leys D.

Biochem Soc Trans. 2003 Jun;31(Pt 3):625-30. Review.

PMID:
12773169
3.

Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes.

McLean KJ, Marshall KR, Richmond A, Hunter IS, Fowler K, Kieser T, Gurcha SS, Besra GS, Munro AW.

Microbiology. 2002 Oct;148(Pt 10):2937-49.

PMID:
12368427
4.

Structure, function and drug targeting in Mycobacterium tuberculosis cytochrome P450 systems.

McLean KJ, Dunford AJ, Neeli R, Driscoll MD, Munro AW.

Arch Biochem Biophys. 2007 Aug 15;464(2):228-40. Epub 2007 Apr 10. Review.

PMID:
17482138
5.

Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.

McLean KJ, Carroll P, Lewis DG, Dunford AJ, Seward HE, Neeli R, Cheesman MR, Marsollier L, Douglas P, Smith WE, Rosenkrands I, Cole ST, Leys D, Parish T, Munro AW.

J Biol Chem. 2008 Nov 28;283(48):33406-16. doi: 10.1074/jbc.M802115200. Epub 2008 Sep 24.

6.

Structural biology and biochemistry of cytochrome P450 systems in Mycobacterium tuberculosis.

McLean KJ, Munro AW.

Drug Metab Rev. 2008;40(3):427-46. doi: 10.1080/03602530802186389 . Review.

PMID:
18642141
7.

The preponderance of P450s in the Mycobacterium tuberculosis genome.

McLean KJ, Clift D, Lewis DG, Sabri M, Balding PR, Sutcliffe MJ, Leys D, Munro AW.

Trends Microbiol. 2006 May;14(5):220-8. Epub 2006 Apr 3. Review.

PMID:
16581251
8.

Expression and characterization of Mycobacterium tuberculosis CYP144: common themes and lessons learned in the M. tuberculosis P450 enzyme family.

Driscoll MD, McLean KJ, Cheesman MR, Jowitt TA, Howard M, Carroll P, Parish T, Munro AW.

Biochim Biophys Acta. 2011 Jan;1814(1):76-87. doi: 10.1016/j.bbapap.2010.05.015. Epub 2010 Jun 8.

PMID:
20621636
9.

CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen.

McLean KJ, Dunford AJ, Sabri M, Neeli R, Girvan HM, Balding PR, Leys D, Seward HE, Marshall KR, Munro AW.

Biochem Soc Trans. 2006 Dec;34(Pt 6):1178-82. Review.

PMID:
17073780
10.

Mycobacterium tuberculosis cytochrome P450 enzymes: a cohort of novel TB drug targets.

Hudson SA, McLean KJ, Munro AW, Abell C.

Biochem Soc Trans. 2012 Jun 1;40(3):573-9. doi: 10.1042/BST20120062. Review.

PMID:
22616869
12.

Genetic and mass spectrometric tools for elucidating the physiological function(s) of cytochrome P450 enzymes from Mycobacterium tuberculosis.

Ouellet H, Chow ED, Guan S, Cox JS, Burlingame AL, de Montellano PR.

Methods Mol Biol. 2013;987:79-94. doi: 10.1007/978-1-62703-321-3_7.

PMID:
23475669
13.

Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode.

Seward HE, Roujeinikova A, McLean KJ, Munro AW, Leys D.

J Biol Chem. 2006 Dec 22;281(51):39437-43. Epub 2006 Oct 6.

14.

Azole-antifungal binding to a novel cytochrome P450 from Mycobacterium tuberculosis: implications for treatment of tuberculosis.

Guardiola-Diaz HM, Foster LA, Mushrush D, Vaz AD.

Biochem Pharmacol. 2001 Jun 15;61(12):1463-70.

PMID:
11377375
15.

The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection.

McLean KJ, Lafite P, Levy C, Cheesman MR, Mast N, Pikuleva IA, Leys D, Munro AW.

J Biol Chem. 2009 Dec 18;284(51):35524-33. doi: 10.1074/jbc.M109.032706. Epub .

16.

New strategies in fighting TB: targeting Mycobacterium tuberculosis-secreted phosphatases MptpA & MptpB.

Silva AP, Tabernero L.

Future Med Chem. 2010 Aug;2(8):1325-37. doi: 10.4155/fmc.10.214. Review.

PMID:
21426021
17.
18.

The Mycobacterium tuberculosis cytochrome P450 system.

Ouellet H, Johnston JB, Ortiz de Montellano PR.

Arch Biochem Biophys. 2010 Jan 1;493(1):82-95. doi: 10.1016/j.abb.2009.07.011. Epub 2009 Jul 25. Review.

19.

Design, synthesis, and structure-activity relationship studies of tryptanthrins as antitubercular agents.

Hwang JM, Oh T, Kaneko T, Upton AM, Franzblau SG, Ma Z, Cho SN, Kim P.

J Nat Prod. 2013 Mar 22;76(3):354-67. doi: 10.1021/np3007167. Epub 2013 Jan 29.

PMID:
23360475
20.

Discovery of novel acetohydroxyacid synthase inhibitors as active agents against Mycobacterium tuberculosis by virtual screening and bioassay.

Wang D, Zhu X, Cui C, Dong M, Jiang H, Li Z, Liu Z, Zhu W, Wang JG.

J Chem Inf Model. 2013 Feb 25;53(2):343-53. doi: 10.1021/ci3004545. Epub 2013 Jan 30.

PMID:
23316686
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk