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Results: 1 to 20 of 192

1.

Inhibition of the p38 MAPK pathway sensitises human colon cancer cells to 5-fluorouracil treatment.

Yang SY, Miah A, Sales KM, Fuller B, Seifalian AM, Winslet M.

Int J Oncol. 2011 Jun;38(6):1695-702. doi: 10.3892/ijo.2011.982. Epub 2011 Mar 21.

PMID:
21424124
[PubMed - indexed for MEDLINE]
2.

Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53.

Borralho PM, Moreira da Silva IB, Aranha MM, Albuquerque C, Nobre Leitão C, Steer CJ, Rodrigues CM.

Biochim Biophys Acta. 2007 Jan;1772(1):40-7. Epub 2006 Sep 16.

PMID:
17056233
[PubMed - indexed for MEDLINE]
Free Article
3.

Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.

Park MT, Choi JA, Kim MJ, Um HD, Bae S, Kang CM, Cho CK, Kang S, Chung HY, Lee YS, Lee SJ.

J Biol Chem. 2003 Dec 12;278(50):50624-34. Epub 2003 Sep 30.

PMID:
14522966
[PubMed - indexed for MEDLINE]
Free Article
4.

P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance.

de la Cruz-Morcillo MA, Valero ML, Callejas-Valera JL, Arias-González L, Melgar-Rojas P, Galán-Moya EM, García-Gil E, García-Cano J, Sánchez-Prieto R.

Oncogene. 2012 Mar 1;31(9):1073-85. doi: 10.1038/onc.2011.321. Epub 2011 Aug 15.

PMID:
21841826
[PubMed - indexed for MEDLINE]
5.

Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells.

Nakagami H, Morishita R, Yamamoto K, Yoshimura SI, Taniyama Y, Aoki M, Matsubara H, Kim S, Kaneda Y, Ogihara T.

Diabetes. 2001 Jun;50(6):1472-81.

PMID:
11375350
[PubMed - indexed for MEDLINE]
Free Article
6.

Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells.

Choi SY, Kim MJ, Kang CM, Bae S, Cho CK, Soh JW, Kim JH, Kang S, Chung HY, Lee YS, Lee SJ.

J Biol Chem. 2006 Mar 17;281(11):7049-59. Epub 2006 Jan 12.

PMID:
16410245
[PubMed - indexed for MEDLINE]
Free Article
7.

Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status.

Violette S, Poulain L, Dussaulx E, Pepin D, Faussat AM, Chambaz J, Lacorte JM, Staedel C, Lesuffleur T.

Int J Cancer. 2002 Apr 1;98(4):498-504.

PMID:
11920608
[PubMed - indexed for MEDLINE]
8.

The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.

Kang YH, Lee SJ.

J Cell Physiol. 2008 Oct;217(1):23-33. doi: 10.1002/jcp.21470.

PMID:
18412143
[PubMed - indexed for MEDLINE]
9.

The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells.

Zhou QM, Wang S, Zhang H, Lu YY, Wang XF, Motoo Y, Su SB.

Acta Pharmacol Sin. 2009 Dec;30(12):1648-58. doi: 10.1038/aps.2009.166.

PMID:
19960010
[PubMed - indexed for MEDLINE]
Free Article
10.

Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells.

Kodach LL, Bos CL, Durán N, Peppelenbosch MP, Ferreira CV, Hardwick JC.

Carcinogenesis. 2006 Mar;27(3):508-16. Epub 2005 Dec 12.

PMID:
16344270
[PubMed - indexed for MEDLINE]
Free Article
11.

Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.

Eur J Pharmacol. 2007 Jun 1;563(1-3):49-60. Epub 2007 Feb 8.

PMID:
17341418
[PubMed - indexed for MEDLINE]
12.

Inhibition of p38 MAPK enhances ABT-737-induced cell death in melanoma cell lines: novel regulation of PUMA.

Keuling AM, Andrew SE, Tron VA.

Pigment Cell Melanoma Res. 2010 Jun;23(3):430-40. doi: 10.1111/j.1755-148X.2010.00698.x. Epub 2010 Mar 22.

PMID:
20337986
[PubMed - indexed for MEDLINE]
13.

Sensitization of apoptotically-resistant breast carcinoma cells to TNF and TRAIL by inhibition of p38 mitogen-activated protein kinase signaling.

Weldon CB, Parker AP, Patten D, Elliott S, Tang Y, Frigo DE, Dugan CM, Coakley EL, Butler NN, Clayton JL, Alam J, Curiel TJ, Beckman BS, Jaffe BM, Burow ME.

Int J Oncol. 2004 Jun;24(6):1473-80.

PMID:
15138590
[PubMed - indexed for MEDLINE]
14.

Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-fluorouracil.

Zhao HY, Ooyama A, Yamamoto M, Ikeda R, Haraguchi M, Tabata S, Furukawa T, Che XF, Zhang S, Oka T, Fukushima M, Nakagawa M, Ono M, Kuwano M, Akiyama S.

Cancer Res. 2008 Sep 1;68(17):7035-41. doi: 10.1158/0008-5472.CAN-07-6496.

PMID:
18757417
[PubMed - indexed for MEDLINE]
Free Article
15.

5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells.

Uchida H, Shinoura N, Kitayama J, Watanabe T, Nagawa H, Hamada H.

J Gene Med. 2003 Apr;5(4):287-99.

PMID:
12692863
[PubMed - indexed for MEDLINE]
16.

Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells.

Li J, Hou N, Faried A, Tsutsumi S, Takeuchi T, Kuwano H.

Ann Surg Oncol. 2009 Mar;16(3):761-71. doi: 10.1245/s10434-008-0260-0. Epub 2008 Dec 31.

PMID:
19116755
[PubMed - indexed for MEDLINE]
17.

Bcl-XL small interfering RNA suppresses the proliferation of 5-fluorouracil-resistant human colon cancer cells.

Zhu H, Guo W, Zhang L, Davis JJ, Teraishi F, Wu S, Cao X, Daniel J, Smythe WR, Fang B.

Mol Cancer Ther. 2005 Mar;4(3):451-6.

PMID:
15767554
[PubMed - indexed for MEDLINE]
Free Article
18.

Phenethyl isothiocyanate (PEITC) inhibits growth of ovarian cancer cells by inducing apoptosis: role of caspase and MAPK activation.

Satyan KS, Swamy N, Dizon DS, Singh R, Granai CO, Brard L.

Gynecol Oncol. 2006 Oct;103(1):261-70. Epub 2006 Apr 19.

PMID:
16624391
[PubMed - indexed for MEDLINE]
19.

Synergistic cytotoxicity and apoptosis of JTE-522, a selective cyclooxygenase-2 inhibitor, and 5-fluorouracil against bladder cancer.

Mizutani Y, Kamoi K, Ukimura O, Kawauchi A, Miki T.

J Urol. 2002 Dec;168(6):2650-4.

PMID:
12442003
[PubMed - indexed for MEDLINE]
20.

Ceramide induces p38 MAPK-dependent apoptosis and Bax translocation via inhibition of Akt in HL-60 cells.

Kim HJ, Oh JE, Kim SW, Chun YJ, Kim MY.

Cancer Lett. 2008 Feb 18;260(1-2):88-95. Epub 2007 Nov 28.

PMID:
18054155
[PubMed - indexed for MEDLINE]

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