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Results: 1 to 20 of 144

1.

siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo.

Khairuddin N, Gantier MP, Blake SJ, Wu SY, Behlke MA, Williams BR, McMillan NA.

Immunol Cell Biol. 2012 Feb;90(2):187-96. doi: 10.1038/icb.2011.19. Epub 2011 Mar 22.

PMID:
21423261
[PubMed - indexed for MEDLINE]
2.

Transcriptional gene silencing of HPV16 E6/E7 induces growth inhibition via apoptosis in vitro and in vivo.

Zhou J, Peng C, Li B, Wang F, Zhou C, Hong D, Ye F, Cheng X, Lü W, Xie X.

Gynecol Oncol. 2012 Feb;124(2):296-302. doi: 10.1016/j.ygyno.2011.10.028. Epub 2011 Nov 3.

PMID:
22056554
[PubMed - indexed for MEDLINE]
3.

Highly potent and specific siRNAs against E6 or E7 genes of HPV16- or HPV18-infected cervical cancers.

Chang JT, Kuo TF, Chen YJ, Chiu CC, Lu YC, Li HF, Shen CR, Cheng AJ.

Cancer Gene Ther. 2010 Dec;17(12):827-36. doi: 10.1038/cgt.2010.38. Epub 2010 Oct 1.

PMID:
20885450
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The synergistic therapeutic effect of cisplatin with Human papillomavirus E6/E7 short interfering RNA on cervical cancer cell lines in vitro and in vivo.

Jung HS, Erkin OC, Kwon MJ, Kim SH, Jung JI, Oh YK, Her SW, Ju W, Choi YL, Song SY, Kim JK, Kim YD, Shim GY, Shin YK.

Int J Cancer. 2012 Apr 15;130(8):1925-36. doi: 10.1002/ijc.26197. Epub 2011 Aug 8.

PMID:
21630254
[PubMed - indexed for MEDLINE]
5.
6.

Gene silencing with siRNA targeting E6/E7 as a therapeutic intervention in a mouse model of cervical cancer.

Jonson AL, Rogers LM, Ramakrishnan S, Downs LS Jr.

Gynecol Oncol. 2008 Nov;111(2):356-64. doi: 10.1016/j.ygyno.2008.06.033. Epub 2008 Aug 27.

PMID:
18755502
[PubMed - indexed for MEDLINE]
7.

Human papillomavirus type 16 (HPV-16) virus-like particle L1-specific CD8+ cytotoxic T lymphocytes (CTLs) are equally effective as E7-specific CD8+ CTLs in killing autologous HPV-16-positive tumor cells in cervical cancer patients: implications for L1 dendritic cell-based therapeutic vaccines.

Bellone S, El-Sahwi K, Cocco E, Casagrande F, Cargnelutti M, Palmieri M, Bignotti E, Romani C, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S, Santin AD.

J Virol. 2009 Jul;83(13):6779-89. doi: 10.1128/JVI.02443-08. Epub 2009 Apr 22.

PMID:
19386711
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Silencing of integrated human papillomavirus-16 oncogenes by small interfering RNA-mediated heterochromatization.

Palanichamy JK, Mehndiratta M, Bhagat M, Ramalingam P, Das B, Das P, Sinha S, Chattopadhyay P.

Mol Cancer Ther. 2010 Jul;9(7):2114-22. doi: 10.1158/1535-7163.MCT-09-0977. Epub 2010 Jun 29.

PMID:
20587668
[PubMed - indexed for MEDLINE]
Free Article
9.

Inhibition of cervical cancer cell growth in vitro and in vivo by lentiviral-vector mediated shRNA targeting the common promoter of HPV16 E6 and E7 oncogenes.

Zhou J, Li B, Peng C, Wang F, Fu Z, Zhou C, Hong D, Ye F, Lü W, Xie X.

Antiviral Res. 2013 May;98(2):305-13. doi: 10.1016/j.antiviral.2013.03.010. Epub 2013 Mar 21.

PMID:
23523766
[PubMed - indexed for MEDLINE]
10.

Optimal induction of HPV DNA vaccine-induced CD8+ T cell responses and therapeutic antitumor effect by antigen engineering and electroporation.

Seo SH, Jin HT, Park SH, Youn JI, Sung YC.

Vaccine. 2009 Sep 25;27(42):5906-12. doi: 10.1016/j.vaccine.2009.07.033. Epub 2009 Aug 3.

PMID:
19651174
[PubMed - indexed for MEDLINE]
11.

RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53.

Sima N, Wang W, Kong D, Deng D, Xu Q, Zhou J, Xu G, Meng L, Lu Y, Wang S, Ma D.

Apoptosis. 2008 Feb;13(2):273-81.

PMID:
18060502
[PubMed - indexed for MEDLINE]
12.

Inhibition of cervical cancer cell growth by human papillomavirus virus-like particles packaged with human papillomavirus oncoprotein short hairpin RNAs.

Bousarghin L, Touze A, Gaud G, Iochmann S, Alvarez E, Reverdiau P, Gaitan J, Jourdan ML, Sizaret PY, Coursaget PL.

Mol Cancer Ther. 2009 Feb;8(2):357-65. doi: 10.1158/1535-7163.MCT-08-0626. Epub 2009 Jan 27.

PMID:
19174559
[PubMed - indexed for MEDLINE]
Free Article
13.

Inhibition of HPV 16 E6 oncogene expression by RNA interference in vitro and in vivo.

Niu XY, Peng ZL, Duan WQ, Wang H, Wang P.

Int J Gynecol Cancer. 2006 Mar-Apr;16(2):743-51.

PMID:
16681755
[PubMed - indexed for MEDLINE]
14.

Paclitaxel combined with siRNA targeting HPV16 oncogenes improves cytotoxicity for cervical carcinoma.

Liu WL, Green N, Seymour LW, Stevenson M.

Cancer Gene Ther. 2009 Oct;16(10):764-75. doi: 10.1038/cgt.2009.24. Epub 2009 Apr 10.

PMID:
19363466
[PubMed - indexed for MEDLINE]
15.

New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer.

Yamato K, Yamada T, Kizaki M, Ui-Tei K, Natori Y, Fujino M, Nishihara T, Ikeda Y, Nasu Y, Saigo K, Yoshinouchi M.

Cancer Gene Ther. 2008 Mar;15(3):140-53. Epub 2007 Dec 21.

PMID:
18157144
[PubMed - indexed for MEDLINE]
16.

Antisense targeting human papillomavirus type 16 E6 and E7 genes contributes to apoptosis and senescence in SiHa cervical carcinoma cells.

Sima N, Wang S, Wang W, Kong D, Xu Q, Tian X, Luo A, Zhou J, Xu G, Meng L, Lu Y, Ma D.

Gynecol Oncol. 2007 Aug;106(2):299-304. Epub 2007 Jun 21.

PMID:
17586029
[PubMed - indexed for MEDLINE]
17.

The PEI-introduced CS shell/PMMA core nanoparticle for silencing the expression of E6/E7 oncogenes in human cervical cells.

Saengkrit N, Sanitrum P, Woramongkolchai N, Saesoo S, Pimpha N, Chaleawlert-Umpon S, Tencomnao T, Puttipipatkhachorn S.

Carbohydr Polym. 2012 Oct 15;90(3):1323-9. doi: 10.1016/j.carbpol.2012.06.079. Epub 2012 Jul 6.

PMID:
22939347
[PubMed - indexed for MEDLINE]
18.

Gene silencing of HPV16 E6/E7 induced by promoter-targeting siRNA in SiHa cells.

Hong D, Lu W, Ye F, Hu Y, Xie X.

Br J Cancer. 2009 Nov 17;101(10):1798-804. doi: 10.1038/sj.bjc.6605344. Epub 2009 Oct 13.

PMID:
19826423
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

[RNA interference: biogenesis molecular mechanisms and its applications in cervical cancer].

Peralta-Zaragoza O, Bermúdez-Morales VH, Madrid-Marina V.

Rev Invest Clin. 2010 Jan-Feb;62(1):63-80. Review. Spanish.

PMID:
20415061
[PubMed - indexed for MEDLINE]
20.

Enhanced specificity of HPV16 E6E7 siRNA by RNA-DNA chimera modification.

Yamato K, Egawa N, Endo S, Ui-Tei K, Yamada T, Saigo K, Hyodo I, Kiyono T, Nakagawa I.

Cancer Gene Ther. 2011 Aug;18(8):587-97. doi: 10.1038/cgt.2011.28. Epub 2011 Jun 10.

PMID:
21660064
[PubMed - indexed for MEDLINE]

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