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Results: 1 to 20 of 104

1.

Enhanced neutralization potency of botulinum neurotoxin antibodies using a red blood cell-targeting fusion protein.

Adekar SP, Segan AT, Chen C, Bermudez R, Elias MD, Selling BH, Kapadnis BP, Simpson LL, Simon PM, Dessain SK.

PLoS One. 2011 Mar 2;6(3):e17491. doi: 10.1371/journal.pone.0017491.

PMID:
21399689
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mechanisms of enhanced neutralization of botulinum neurotoxin by monoclonal antibodies conjugated to antibodies specific for the erythrocyte complement receptor.

Sharma R, Zhao H, Al-Saleem FH, Ubaid AS, Puligedda RD, Segan AT, Lindorfer MA, Bermudez R, Elias M, Adekar SP, Simpson LL, Taylor RP, Dessain SK.

Mol Immunol. 2014 Feb;57(2):247-54. doi: 10.1016/j.molimm.2013.09.005. Epub 2013 Nov 1.

PMID:
24184879
[PubMed - indexed for MEDLINE]
Free Article
3.

Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralization.

Smith TJ, Lou J, Geren IN, Forsyth CM, Tsai R, Laporte SL, Tepp WH, Bradshaw M, Johnson EA, Smith LA, Marks JD.

Infect Immun. 2005 Sep;73(9):5450-7.

PMID:
16113261
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Botulinum neurotoxin neutralizing activity of immune globulin (IG) purified from clinical volunteers vaccinated with recombinant botulinum vaccine (rBV A/B).

Shearer JD, Vassar ML, Swiderski W, Metcalfe K, Niemuth N, Henderson I.

Vaccine. 2010 Oct 21;28(45):7313-8. doi: 10.1016/j.vaccine.2010.08.076. Epub 2010 Sep 1.

PMID:
20816903
[PubMed - indexed for MEDLINE]
5.

Characterization of the monoclonal antibody response to botulinum neurotoxin type A in the complexed and uncomplexed forms.

Zhao H, Nakamura K, Kohda T, Mukamoto M, Kozaki S.

Jpn J Infect Dis. 2012;65(2):138-45.

PMID:
22446121
[PubMed - indexed for MEDLINE]
Free Article
6.

Efficient serum clearance of botulinum neurotoxin achieved using a pool of small antitoxin binding agents.

Sepulveda J, Mukherjee J, Tzipori S, Simpson LL, Shoemaker CB.

Infect Immun. 2010 Feb;78(2):756-63. doi: 10.1128/IAI.01084-09. Epub 2009 Nov 16.

PMID:
19917718
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Neutralizing antibodies of botulinum neurotoxin serotype A screened from a fully synthetic human antibody phage display library.

Yu R, Wang S, Yu YZ, Du WS, Yang F, Yu WY, Sun ZW.

J Biomol Screen. 2009 Sep;14(8):991-8. doi: 10.1177/1087057109343206. Epub 2009 Sep 2.

PMID:
19726786
[PubMed - indexed for MEDLINE]
8.

Fine and domain-level epitope mapping of botulinum neurotoxin type A neutralizing antibodies by yeast surface display.

Levy R, Forsyth CM, LaPorte SL, Geren IN, Smith LA, Marks JD.

J Mol Biol. 2007 Jan 5;365(1):196-210. Epub 2006 Oct 3.

PMID:
17059824
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The receptor binding domain of botulinum neurotoxin serotype A (BoNT/A) inhibits BoNT/A and BoNT/E intoxications in vivo.

Ben David A, Diamant E, Barnea A, Rosen O, Torgeman A, Zichel R.

Clin Vaccine Immunol. 2013 Aug;20(8):1266-73. doi: 10.1128/CVI.00268-13. Epub 2013 Jun 12.

PMID:
23761665
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Epitope characterization of sero-specific monoclonal antibody to Clostridium botulinum neurotoxin type A.

Corbett CR, Ballegeer E, Weedmark KA, Elias MD, Al-Saleem FH, Ancharski DM, Simpson LL, Berry JD.

Hybridoma (Larchmt). 2011 Dec;30(6):503-10. doi: 10.1089/hyb.2011.0032.

PMID:
22149274
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Characterization of botulinum neurotoxin type A neutralizing monoclonal antibodies and influence of their half-lives on therapeutic activity.

Mazuet C, Dano J, Popoff MR, Créminon C, Volland H.

PLoS One. 2010 Aug 26;5(8):e12416. doi: 10.1371/journal.pone.0012416.

PMID:
20865035
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Antibody protection against botulinum neurotoxin intoxication in mice.

Cheng LW, Stanker LH, Henderson TD 2nd, Lou J, Marks JD.

Infect Immun. 2009 Oct;77(10):4305-13. doi: 10.1128/IAI.00405-09. Epub 2009 Aug 3.

PMID:
19651864
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Purification, potency, and efficacy of the botulinum neurotoxin type A binding domain from Pichia pastoris as a recombinant vaccine candidate.

Byrne MP, Smith TJ, Montgomery VA, Smith LA.

Infect Immun. 1998 Oct;66(10):4817-22.

PMID:
9746584
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Subunit vaccine efficacy against Botulinum neurotoxin subtypes.

Henkel JS, Tepp WH, Przedpelski A, Fritz RB, Johnson EA, Barbieri JT.

Vaccine. 2011 Oct 13;29(44):7688-95. doi: 10.1016/j.vaccine.2011.07.134. Epub 2011 Aug 10.

PMID:
21839134
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin.

Garcia-Rodriguez C, Geren IN, Lou J, Conrad F, Forsyth C, Wen W, Chakraborti S, Zao H, Manzanarez G, Smith TJ, Brown J, Tepp WH, Liu N, Wijesuriya S, Tomic MT, Johnson EA, Smith LA, Marks JD.

Protein Eng Des Sel. 2011 Mar;24(3):321-31. doi: 10.1093/protein/gzq111. Epub 2010 Dec 13.

PMID:
21149386
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Rapid immune responses to a botulinum neurotoxin Hc subunit vaccine through in vivo targeting to antigen-presenting cells.

White DM, Pellett S, Jensen MA, Tepp WH, Johnson EA, Arnason BG.

Infect Immun. 2011 Aug;79(8):3388-96. doi: 10.1128/IAI.00166-11. Epub 2011 May 16.

PMID:
21576339
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Detection of botulinum neurotoxin serotype B at sub mouse LD(50) levels by a sandwich immunoassay and its application to toxin detection in milk.

Scotcher MC, Cheng LW, Stanker LH.

PLoS One. 2010 Jun 10;5(6):e11047. doi: 10.1371/journal.pone.0011047.

PMID:
20548779
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Characterization of neutralizing mouse-human chimeric and shuffling antibodies against botulinum neurotoxin A.

Mukamoto M, Maeda H, Kohda T, Nozaki C, Takahashi M, Kozaki S.

Microbiol Immunol. 2012 Nov;56(11):748-55. doi: 10.1111/j.1348-0421.2012.00503.x.

PMID:
22938032
[PubMed - indexed for MEDLINE]
19.

Sheep monoclonal antibodies prevent systemic effects of botulinum neurotoxin A1.

Mukherjee J, McCann C, Ofori K, Hill J, Baldwin K, Shoemaker CB, Harrison P, Tzipori S.

Toxins (Basel). 2012 Dec;4(12):1565-81.

PMID:
23342681
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Potent neutralization of botulinum neurotoxin/B by synergistic action of antibodies recognizing protein and ganglioside receptor binding domain.

Chen C, Wang S, Wang H, Mao X, Zhang T, Ji G, Shi X, Xia T, Lu W, Zhang D, Dai J, Guo Y.

PLoS One. 2012;7(8):e43845. doi: 10.1371/journal.pone.0043845. Epub 2012 Aug 29.

PMID:
22952786
[PubMed - indexed for MEDLINE]
Free PMC Article

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