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Results: 1 to 20 of 91

1.

Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis.

So EY, Ausman M, Saeki T, Ouchi T.

Cell Death Dis. 2011 Mar 10;2:e128. doi: 10.1038/cddis.2011.9.

PMID:
21390062
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition.

Horton JK, Stefanick DF, Zeng JY, Carrozza MJ, Wilson SH.

DNA Repair (Amst). 2011 Feb 7;10(2):225-34. doi: 10.1016/j.dnarep.2010.11.003. Epub 2010 Dec 3.

PMID:
21130714
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

ATM-dependent CHK2 activation induced by anticancer agent, irofulven.

Wang J, Wiltshire T, Wang Y, Mikell C, Burks J, Cunningham C, Van Laar ES, Waters SJ, Reed E, Wang W.

J Biol Chem. 2004 Sep 17;279(38):39584-92. Epub 2004 Jul 20.

PMID:
15269203
[PubMed - indexed for MEDLINE]
Free Article
4.

Point mutation at the Nbs1 Threonine 278 site does not affect mouse development, but compromises the Chk2 and Smc1 phosphorylation after DNA damage.

Li T, Wang ZQ.

Mech Ageing Dev. 2011 Aug;132(8-9):382-8. doi: 10.1016/j.mad.2011.05.001. Epub 2011 Jun 2.

PMID:
21664921
[PubMed - indexed for MEDLINE]
5.

DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.

Caporali S, Falcinelli S, Starace G, Russo MT, Bonmassar E, Jiricny J, D'Atri S.

Mol Pharmacol. 2004 Sep;66(3):478-91.

PMID:
15322239
[PubMed - indexed for MEDLINE]
Free Article
6.

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint.

Yazdi PT, Wang Y, Zhao S, Patel N, Lee EY, Qin J.

Genes Dev. 2002 Mar 1;16(5):571-82.

PMID:
11877377
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway.

Kitagawa R, Bakkenist CJ, McKinnon PJ, Kastan MB.

Genes Dev. 2004 Jun 15;18(12):1423-38. Epub 2004 Jun 2.

PMID:
15175241
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage.

Kim ST, Xu B, Kastan MB.

Genes Dev. 2002 Mar 1;16(5):560-70.

PMID:
11877376
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Rad50 depletion impacts upon ATR-dependent DNA damage responses.

Zhong H, Bryson A, Eckersdorff M, Ferguson DO.

Hum Mol Genet. 2005 Sep 15;14(18):2685-93. Epub 2005 Aug 8.

PMID:
16087684
[PubMed - indexed for MEDLINE]
Free Article
10.

Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites.

Das KC, Dashnamoorthy R.

Am J Physiol Lung Cell Mol Physiol. 2004 Jan;286(1):L87-97. Epub 2003 Sep 5.

PMID:
12959929
[PubMed - indexed for MEDLINE]
Free Article
11.

Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage.

Helt CE, Cliby WA, Keng PC, Bambara RA, O'Reilly MA.

J Biol Chem. 2005 Jan 14;280(2):1186-92. Epub 2004 Nov 8.

PMID:
15533933
[PubMed - indexed for MEDLINE]
Free Article
12.

Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells.

Tomimatsu N, Mukherjee B, Burma S.

EMBO Rep. 2009 Jun;10(6):629-35. doi: 10.1038/embor.2009.60. Epub 2009 May 15.

PMID:
19444312
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress.

Myers K, Gagou ME, Zuazua-Villar P, Rodriguez R, Meuth M.

PLoS Genet. 2009 Jan;5(1):e1000324. doi: 10.1371/journal.pgen.1000324. Epub 2009 Jan 2.

PMID:
19119425
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

HCLK2 is required for activity of the DNA damage response kinase ATR.

Rendtlew Danielsen JM, Larsen DH, Schou KB, Freire R, Falck J, Bartek J, Lukas J.

J Biol Chem. 2009 Feb 13;284(7):4140-7. doi: 10.1074/jbc.M808174200. Epub 2008 Dec 19.

PMID:
19097996
[PubMed - indexed for MEDLINE]
Free Article
15.

E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.

Powers JT, Hong S, Mayhew CN, Rogers PM, Knudsen ES, Johnson DG.

Mol Cancer Res. 2004 Apr;2(4):203-14.

PMID:
15140942
[PubMed - indexed for MEDLINE]
Free Article
16.

Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK.

J Biol Chem. 2003 Apr 25;278(17):14806-11. Epub 2003 Feb 14.

PMID:
12588868
[PubMed - indexed for MEDLINE]
Free Article
17.

The ATM-dependent DNA damage signaling pathway.

Kitagawa R, Kastan MB.

Cold Spring Harb Symp Quant Biol. 2005;70:99-109. Review.

PMID:
16869743
[PubMed - indexed for MEDLINE]
18.

Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage.

Ha K, Fiskus W, Rao R, Balusu R, Venkannagari S, Nalabothula NR, Bhalla KN.

Mol Cancer Ther. 2011 Jul;10(7):1194-206. doi: 10.1158/1535-7163.MCT-11-0094. Epub 2011 May 12.

PMID:
21566061
[PubMed - indexed for MEDLINE]
Free Article
19.

Requirement of MTA1 in ATR-mediated DNA damage checkpoint function.

Li DQ, Ohshiro K, Khan MN, Kumar R.

J Biol Chem. 2010 Jun 25;285(26):19802-12. doi: 10.1074/jbc.M109.085258. Epub 2010 Apr 28.

PMID:
20427275
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.

Yan T, Desai AB, Jacobberger JW, Sramkoski RM, Loh T, Kinsella TJ.

Mol Cancer Ther. 2004 Sep;3(9):1147-57.

PMID:
15367709
[PubMed - indexed for MEDLINE]
Free Article

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