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Results: 1 to 20 of 103

Similar articles for PubMed (Select 21389349)

1.

The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1.

Syeda F, Fagan RL, Wean M, Avvakumov GV, Walker JR, Xue S, Dhe-Paganon S, Brenner C.

J Biol Chem. 2011 Apr 29;286(17):15344-51. doi: 10.1074/jbc.M110.209882. Epub 2011 Mar 9.

2.

The DNA methyltransferase Dnmt1 directly interacts with the SET and RING finger-associated (SRA) domain of the multifunctional protein Uhrf1 to facilitate accession of the catalytic center to hemi-methylated DNA.

Berkyurek AC, Suetake I, Arita K, Takeshita K, Nakagawa A, Shirakawa M, Tajima S.

J Biol Chem. 2014 Jan 3;289(1):379-86. doi: 10.1074/jbc.M113.523209. Epub 2013 Nov 19.

3.

Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain.

Bashtrykov P, Rajavelu A, Hackner B, Ragozin S, Carell T, Jeltsch A.

Chembiochem. 2014 Mar 21;15(5):743-8. doi: 10.1002/cbic.201300740. Epub 2014 Feb 13.

PMID:
24532244
4.

The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.

Bashtrykov P, Jankevicius G, Jurkowska RZ, Ragozin S, Jeltsch A.

J Biol Chem. 2014 Feb 14;289(7):4106-15. doi: 10.1074/jbc.M113.528893. Epub 2013 Dec 24.

6.

Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1).

Takeshita K, Suetake I, Yamashita E, Suga M, Narita H, Nakagawa A, Tajima S.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9055-9. doi: 10.1073/pnas.1019629108. Epub 2011 Apr 25.

7.

RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylation.

Wu BK, Mei SC, Brenner C.

Cell Cycle. 2014;13(20):3222-31. doi: 10.4161/15384101.2014.950886.

PMID:
25485502
8.

Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.

Song J, Rechkoblit O, Bestor TH, Patel DJ.

Science. 2011 Feb 25;331(6020):1036-40. doi: 10.1126/science.1195380. Epub 2010 Dec 16.

9.

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism.

Arita K, Ariyoshi M, Tochio H, Nakamura Y, Shirakawa M.

Nature. 2008 Oct 9;455(7214):818-21. doi: 10.1038/nature07249. Epub 2008 Sep 3.

PMID:
18772891
10.

The DNMT1 target recognition domain resides in the N terminus.

Araujo FD, Croteau S, Slack AD, Milutinovic S, Bigey P, Price GB, Zannis-Hadjopoulos M, Szyf M.

J Biol Chem. 2001 Mar 9;276(10):6930-6. Epub 2000 Dec 4. Erratum in: J Biol Chem. 2007 May 4;282(18):13928. Zannis-Hajopoulos, M [corrected to Zannis-Hadjopoulos, M].

11.
12.

Crystal Structure of Human DNA Methyltransferase 1.

Zhang ZM, Liu S, Lin K, Luo Y, Perry JJ, Wang Y, Song J.

J Mol Biol. 2015 Jun 10. pii: S0022-2836(15)00341-1. doi: 10.1016/j.jmb.2015.06.001. [Epub ahead of print]

PMID:
26070743
13.

Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain.

Bashtrykov P, Jankevicius G, Smarandache A, Jurkowska RZ, Ragozin S, Jeltsch A.

Chem Biol. 2012 May 25;19(5):572-8. doi: 10.1016/j.chembiol.2012.03.010.

14.

CXXC domain of human DNMT1 is essential for enzymatic activity.

Pradhan M, Estève PO, Chin HG, Samaranayke M, Kim GD, Pradhan S.

Biochemistry. 2008 Sep 23;47(38):10000-9. doi: 10.1021/bi8011725. Epub 2008 Aug 29.

PMID:
18754681
15.

Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.

Frauer C, Rottach A, Meilinger D, Bultmann S, Fellinger K, Hasenöder S, Wang M, Qin W, Söding J, Spada F, Leonhardt H.

PLoS One. 2011 Feb 2;6(2):e16627. doi: 10.1371/journal.pone.0016627.

17.

Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation.

Song J, Teplova M, Ishibe-Murakami S, Patel DJ.

Science. 2012 Feb 10;335(6069):709-12. doi: 10.1126/science.1214453.

18.

Processive methylation of hemimethylated CpG sites by mouse Dnmt1 DNA methyltransferase.

Vilkaitis G, Suetake I, Klimasauskas S, Tajima S.

J Biol Chem. 2005 Jan 7;280(1):64-72. Epub 2004 Oct 27.

19.

De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases.

Gowher H, Stockdale CJ, Goyal R, Ferreira H, Owen-Hughes T, Jeltsch A.

Biochemistry. 2005 Jul 26;44(29):9899-904.

PMID:
16026162
20.

Dnmt1 structure and function.

Svedružić ŽM.

Prog Mol Biol Transl Sci. 2011;101:221-54. doi: 10.1016/B978-0-12-387685-0.00006-8. Review.

PMID:
21507353
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