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Results: 1 to 20 of 114

1.

Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress.

Ozden O, Park SH, Kim HS, Jiang H, Coleman MC, Spitz DR, Gius D.

Aging (Albany NY). 2011 Feb;3(2):102-7. Review.

PMID:
21386137
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Exploring the electrostatic repulsion model in the role of Sirt3 in directing MnSOD acetylation status and enzymatic activity.

Zhu Y, Park SH, Ozden O, Kim HS, Jiang H, Vassilopoulos A, Spitz DR, Gius D.

Free Radic Biol Med. 2012 Aug 15;53(4):828-33. doi: 10.1016/j.freeradbiomed.2012.06.020. Epub 2012 Jun 23. Review.

PMID:
22732184
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Regulation of MnSOD enzymatic activity by Sirt3 connects the mitochondrial acetylome signaling networks to aging and carcinogenesis.

Tao R, Vassilopoulos A, Parisiadou L, Yan Y, Gius D.

Antioxid Redox Signal. 2014 Apr 1;20(10):1646-54. doi: 10.1089/ars.2013.5482. Epub 2013 Sep 14.

PMID:
23886445
[PubMed - in process]
4.

Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

Tao R, Coleman MC, Pennington JD, Ozden O, Park SH, Jiang H, Kim HS, Flynn CR, Hill S, Hayes McDonald W, Olivier AK, Spitz DR, Gius D.

Mol Cell. 2010 Dec 22;40(6):893-904. doi: 10.1016/j.molcel.2010.12.013.

PMID:
21172655
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mitochondrial localization of fission yeast manganese superoxide dismutase is required for its lysine acetylation and for cellular stress resistance and respiratory growth.

Takahashi H, Suzuki T, Shirai A, Matsuyama A, Dohmae N, Yoshida M.

Biochem Biophys Res Commun. 2011 Mar 4;406(1):42-6. doi: 10.1016/j.bbrc.2011.01.103. Epub 2011 Feb 2.

PMID:
21295010
[PubMed - indexed for MEDLINE]
6.

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS.

Chen Y, Zhang J, Lin Y, Lei Q, Guan KL, Zhao S, Xiong Y.

EMBO Rep. 2011 Jun;12(6):534-41. doi: 10.1038/embor.2011.65. Epub 2011 May 13.

PMID:
21566644
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Sirt3, Mitochondrial ROS, Ageing, and Carcinogenesis.

Park SH, Ozden O, Jiang H, Cha YI, Pennington JD, Aykin-Burns N, Spitz DR, Gius D, Kim HS.

Int J Mol Sci. 2011;12(9):6226-39. doi: 10.3390/ijms12096226. Epub 2011 Sep 23.

PMID:
22016654
[PubMed - in process]
Free PMC Article
8.

SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage.

Tseng AH, Shieh SS, Wang DL.

Free Radic Biol Med. 2013 Oct;63:222-34. doi: 10.1016/j.freeradbiomed.2013.05.002. Epub 2013 May 7.

PMID:
23665396
[PubMed - indexed for MEDLINE]
9.

Skeletal muscle MnSOD, mitochondrial complex II, and SIRT3 enzyme activities are decreased in maternal obesity during human pregnancy and gestational diabetes mellitus.

Boyle KE, Newsom SA, Janssen RC, Lappas M, Friedman JE.

J Clin Endocrinol Metab. 2013 Oct;98(10):E1601-9. doi: 10.1210/jc.2013-1943. Epub 2013 Aug 16.

PMID:
23956348
[PubMed - indexed for MEDLINE]
10.

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis.

Fernandez-Marcos PJ, Jeninga EH, Canto C, Harach T, de Boer VC, Andreux P, Moullan N, Pirinen E, Yamamoto H, Houten SM, Schoonjans K, Auwerx J.

Sci Rep. 2012;2:425. doi: 10.1038/srep00425. Epub 2012 May 28.

PMID:
22645641
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase.

Li S, Yan T, Yang JQ, Oberley TD, Oberley LW.

Cancer Res. 2000 Jul 15;60(14):3927-39.

PMID:
10919671
[PubMed - indexed for MEDLINE]
Free Article
12.

Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation.

Qiu X, Brown K, Hirschey MD, Verdin E, Chen D.

Cell Metab. 2010 Dec 1;12(6):662-7. doi: 10.1016/j.cmet.2010.11.015.

PMID:
21109198
[PubMed - indexed for MEDLINE]
Free Article
13.

Metabolic regulation by SIRT3: implications for tumorigenesis.

Finley LW, Haigis MC.

Trends Mol Med. 2012 Sep;18(9):516-23. doi: 10.1016/j.molmed.2012.05.004. Epub 2012 Jun 27. Review.

PMID:
22749020
[PubMed - indexed for MEDLINE]
14.

Oxidative stress response elicited by mitochondrial dysfunction: implication in the pathophysiology of aging.

Wang CH, Wu SB, Wu YT, Wei YH.

Exp Biol Med (Maywood). 2013 May;238(5):450-60. doi: 10.1177/1535370213493069. Review.

PMID:
23856898
[PubMed - indexed for MEDLINE]
15.

Estrogen suppresses brain mitochondrial oxidative stress in female and male rats.

Razmara A, Duckles SP, Krause DN, Procaccio V.

Brain Res. 2007 Oct 24;1176:71-81. Epub 2007 Aug 24.

PMID:
17889838
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heart.

Sack MN.

Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2191-7. doi: 10.1152/ajpheart.00199.2011. Epub 2011 Oct 7. Review.

PMID:
21984547
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Induction of apoptosis by adenovirus-mediated manganese superoxide dismutase overexpression in SV-40-transformed human fibroblasts.

Kim A, Oberley LW, Oberley TD.

Free Radic Biol Med. 2005 Nov 1;39(9):1128-41.

PMID:
16214029
[PubMed - indexed for MEDLINE]
18.

SIRT3 regulation of mitochondrial oxidative stress.

Bause AS, Haigis MC.

Exp Gerontol. 2013 Jul;48(7):634-9. doi: 10.1016/j.exger.2012.08.007. Epub 2012 Aug 31. Review.

PMID:
22964489
[PubMed - indexed for MEDLINE]
19.

Inhibition of cell growth in NIH/3T3 fibroblasts by overexpression of manganese superoxide dismutase: mechanistic studies.

Li N, Oberley TD, Oberley LW, Zhong W.

J Cell Physiol. 1998 Jun;175(3):359-69.

PMID:
9572481
[PubMed - indexed for MEDLINE]
20.

Manganese superoxide dismutase vs. p53: regulation of mitochondrial ROS.

Holley AK, Dhar SK, St Clair DK.

Mitochondrion. 2010 Nov;10(6):649-61. doi: 10.1016/j.mito.2010.06.003. Epub 2010 Jul 1. Review.

PMID:
20601193
[PubMed - indexed for MEDLINE]

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